Search Results - "Truong, Andrew S"
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Real-time imaging of cancer cell chemotaxis in paper-based scaffolds
Published in Analyst (London) (01-01-2016)“…Cellular migration is the movement of cells, cultured as a monolayer; cellular invasion is similar to migration, but requires the cells to move through a…”
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Entinostat induces antitumor immune responses through immune editing of tumor neoantigens
Published in The Journal of clinical investigation (16-08-2021)“…Although immune-checkpoint inhibitors (ICIs) have been a remarkable advancement in bladder cancer treatment, the response rate to single-agent ICIs remains…”
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Oxygen as a chemoattractant: confirming cellular hypoxia in paper-based invasion assays
Published in Analyst (London) (21-06-2016)“…Low oxygen tension, or hypoxia, is a common occurrence in solid tumors. Hypoxia is a master regulator of cellular phenotype, and is associated with increased…”
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4
Tracking the Invasion of Small Numbers of Cells in Paper-Based Assays with Quantitative PCR
Published in Analytical chemistry (Washington) (17-11-2015)“…Paper-based scaffolds are an attractive material for culturing mammalian cells in a three-dimensional environment. There are a number of previously published…”
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Quantifying oxygen in paper-based cell cultures with luminescent thin film sensors
Published in Analytical and bioanalytical chemistry (01-04-2016)“…Paper-based scaffolds are an attractive material for generating 3D tissue-like cultures because paper is readily available and does not require specialized…”
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Abstract A13: Entinostat enhances antitumor immune responses and cooperates with PD-1 blockade in bladder cancer mouse models
Published in Clinical cancer research (01-08-2020)“…Abstract Bladder cancer harbors a high frequency of somatic mutations that occur randomly across the genome. A fraction of these mutations can be expressed and…”
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Abstract 5156: The mutagenic effects of APOBEC3A and APOBEC3B in urothelial carcinoma
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract APOBEC3A (A3A) and APOBEC3B (A3B) are members of a family of cytidine deaminase enzymes that catalyze the removal of an amino group from cytosine…”
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Abstract 919: APOBEC3 promotes tumor progression, squamous differentiation and metastasis in bladder cancer mouse model
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract Bladder cancer is the sixth most common type of cancer in the United States. In 2021, there are an estimated 83,730 new cases and 17,200 deaths from…”
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Abstract 2748: Antitumor activity of HDAC inhibition in bladder cancer mouse models correlates with enhanced immune response
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Aberrant chromatin remodeling by epigenetic modifier proteins such as histone deacetylases (HDACs) is common within many types of cancer, including…”
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Abstract 682: Development of novel eIF4E inhibitors to potently and selectively suppress tumor growth across multiple indications
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Despite considerable progress in treating cancer, drug resistance remains the primary hurdle to achieving cures in patients. Tumors often develop…”
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Abstract B026: APOBEC3 promotes squamous differentiation via IL1A/AP-1 signaling
Published in Clinical cancer research (17-05-2024)“…Abstract The APOBEC family of cytidine deaminase enzymes catalyze the conversion of cytosine to uracil in ssDNA and RNA substrates. The resulting C to U…”
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