Search Results - "Trumbo, Caitlin M"
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Electrochemical Assessment of Sequence Selective DNA Damage from Myoglogin and Cytochrome P450 Bioactivated Benzo[a]pyrene at TP53 Oligomers
Published in Electroanalysis (New York, N.Y.) (01-11-2016)“…Enzymatic bioactivation of an otherwise non‐reactive species into a reactive one can lead to significant health problems in vivo. Bioactivation of…”
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Journal Article -
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Electrochemical Study on the Effects of Epigenetic Cytosine Methylation on Anti-Benzo[a]pyrene Diol Epoxide Damage at TP53 Oligomers
Published in Analytical chemistry (Washington) (15-01-2013)“…Anti-benzo[a]pyrene-r-7,t-8-dihydrodiol-t-9,10-epoxide (anti-BPDE) is a known carcinogen that damages DNA, and this damage is influenced by the DNA sequence…”
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Journal Article -
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Electrochemical detection of benzo[a]pyrene-induced DNA damage at TP53 oligomers: Impact of 5'-methyl cytosine and bioactivation on the genotoxicity process
Published 01-01-2014“…DNA houses the blueprint that dictates how an organism will develop. However, DNA features numerous reactive sites that can be attacked by chemicals and…”
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Dissertation