Search Results - "Truman, Matt"
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Intercalated combination of chemotherapy and erlotinib for patients with advanced stage non-small-cell lung cancer (FASTACT-2): a randomised, double-blind trial
Published in The lancet oncology (01-07-2013)“…Summary Background The results of FASTACT, a randomised, placebo-controlled, phase 2 study, showed that intercalated chemotherapy and erlotinib significantly…”
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Comparison of a voclosporin-based triple immunosuppressive therapy to high-dose glucocorticoid-based immunosuppressive therapy: a propensity analysis of the AURA-LV and AURORA 1 studies and ALMS
Published in Lupus science & medicine (09-11-2024)“…Introduction High-dose glucocorticoid (GC)-based dual immunosuppressive treatment regimens are still frequently used in active lupus nephritis (LN) despite…”
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P87 Comparison of a voclosporin-based, triple immunotherapy regimen to high-dose glucocorticoid-based immunosuppressive therapy: a propensity analysis of the AURA-LV plus AURORA 1 studies and ALMS
Published in Lupus science & medicine (14-03-2024)“…ObjectiveEarly reduction in proteinuria after initial treatment has been associated with improved long-term kidney outcomes in lupus nephritis (LN). The…”
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A randomised, cross-over study comparing injection site pain with subcutaneous epoetin beta and subcutaneous darbepoetin alfa in patients with chronic kidney disease
Published in Current medical research and opinion (01-08-2008)“…ABSTRACT Objective: To compare injection site pain of subcutaneous (sc) epoetin beta and darbepoetin alfa in adult patients with chronic kidney disease…”
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Efficacy and Safety of Voclosporin Over 3 Years in Patients With Severe Lupus Nephritis: FR-OR58
Published in Journal of the American Society of Nephrology (01-11-2022)Get full text
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Voclosporin Is Effective in Achieving Complete Renal Response in Severe Lupus Nephritis: SA-OR31
Published in Journal of the American Society of Nephrology (01-10-2021)Get full text
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468 Voclosporin-based, triple-immunosuppressive therapy vs high-dose glucocorticoid-based dual-immunotherapy for lupus nephritis: a propensity analysis
Published in Nephrology, dialysis, transplantation (23-05-2024)“…Abstract Background and Aims Voclosporin is a second generation calcineurin inhibitor (CNI) approved for the treatment of adults with active lupus nephritis…”
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Detection and Dynamic Changes of EGFR Mutations from Circulating Tumor DNA as a Predictor of Survival Outcomes in NSCLC Patients Treated with First-line Intercalated Erlotinib and Chemotherapy
Published in Clinical cancer research (15-07-2015)“…Blood-based circulating-free (cf) tumor DNA may be an alternative to tissue-based EGFR mutation testing in NSCLC. This exploratory analysis compares matched…”
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Reasons for Biologic and Targeted Synthetic Disease-modifying Antirheumatic Drug Cessation and Persistence of Second-line Treatment in a Rheumatoid Arthritis Dataset
Published in Journal of rheumatology (01-08-2020)“…Objective. To provide real-world evidence about the reasons why Australian rheumatologists cease biologic (b) and targeted synthetic (ts) disease-modifying…”
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Results From the First Multicenter, Open-label, Phase IIIb Study Investigating the Combination of Pertuzumab With Subcutaneous Trastuzumab and a Taxane in Patients With HER2-positive Metastatic Breast Cancer (SAPPHIRE)
Published in Clinical breast cancer (01-06-2019)“…The primary objective of this study was to assess the safety and tolerability of combination pertuzumab, subcutaneous trastuzumab (Herceptin), and…”
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Once-Monthly Continuous Erythropoietin Receptor Activator (C.E.R.A.) in Patients with Hemodialysis-Dependent Chronic Kidney Disease: Pooled Data from Phase III Trials
Published in Advances in therapy (01-04-2016)“…Introduction Erythropoiesis-stimulating agents and iron are commonly used in patients with chronic kidney disease with the aim of correcting anemia and…”
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Safety of Subcutaneous Administration of Rituximab during the First-Line Treatment of Patients with Non-Hodgkin Lymphoma: The MabRella Study
Published in Blood (02-12-2016)“…Background: Rituximab, administered intravenously (IV), is the mainstay of treatment for CD20+ B-cell non-Hodgkin lymphoma (NHL). A subcutaneous (SC)…”
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A multi‐centre, single‐arm, open‐label study evaluating the safety and efficacy of fixed dose rituximab in patients with refractory, relapsed or chronic idiopathic thrombocytopenic purpura (R‐ITP1000 study)
Published in British journal of haematology (01-10-2014)“…Summary The efficacy of a fixed‐dose rituximab schedule was prospectively explored in primary/acute refractory, relapsed or chronic (platelet count >10 × 109/l…”
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Identification of clinical and serological factors during induction treatment of lupus nephritis that are associated with renal outcome
Published in Lupus science & medicine (2015)“…Objective To identify factors associated with clinical outcome in patients with lupus nephritis. Methods Data from the Aspreva Lupus Management Study (ALMS)…”
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Safety and Efficacy of Bevacizumab Plus Standard-of-Care Treatment Beyond Disease Progression in Patients With Advanced Non-Small Cell Lung Cancer: The AvaALL Randomized Clinical Trial
Published in JAMA oncology (01-12-2018)“…Bevacizumab treatment beyond progression has been investigated in breast and metastatic colorectal cancers. Avastin in All Lines Lung (AvaALL) is the first…”
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Effectiveness of biologics in Australian patients with rheumatoid arthritis: a large observational study: REAL
Published in Internal medicine journal (01-10-2018)“…Background The comparative effectiveness of biologic treatment regimens in a real world Australian population is unknown. Aim To assess the effectiveness of…”
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Tumor marker analyses from the phase III, placebo-controlled, FASTACT-2 study of intercalated erlotinib with gemcitabine/platinum in the first-line treatment of advanced non-small-cell lung cancer
Published in Lung cancer (Amsterdam, Netherlands) (01-08-2016)“…Highlights • EGFR mutation is the main predictive biomarker for better outcomes with erlotinib. • Expression of HER2 and HER3 were not independently predictive…”
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Predictors of treatment response in a lupus nephritis population: lessons from the Aspreva Lupus Management Study (ALMS) trial
Published in Lupus science & medicine (01-05-2022)“…ObjectivesTo identify predictors of overall lupus and lupus nephritis (LN) responses in patients with LN.MethodsData from the Aspreva Lupus Management Study…”
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Detection of EGFR-activating mutations from plasma DNA as a potent predictor of survival outcomes in FASTACT 2: A randomized phase III study on intercalated combination of erlotinib (E) and chemotherapy (C)
Published in Journal of clinical oncology (20-05-2013)“…Abstract only 8021 Background: Biomarker analysis of tumor from FASTACT 2 confirmed predictive power of EGFR mut on the benefit of intercalated combination of…”
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