Search Results - "Trullas, R"
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The Armc10/SVH gene: genome context, regulation of mitochondrial dynamics and protection against Aβ-induced mitochondrial fragmentation
Published in Cell death & disease (01-04-2014)“…Mitochondrial function and dynamics are essential for neurotransmission, neural function and neuronal viability. Recently, we showed that the…”
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Inhibition of cyclin-dependent kinases is neuroprotective in 1-methyl-4-phenylpyridinium-induced apoptosis in neurons
Published in Neuroscience (25-04-2007)“…Abstract The biochemical pathways involved in neuronal cell death in Parkinson’s disease are not completely characterized. Mitochondrial dysfunction,…”
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Differential responses to anxiogenic drugs in a mouse model of panic disorder as revealed by Fos immunocytochemistry in specific areas of the fear circuitry
Published in Amino acids (01-11-2007)“…Sensitivity to pharmacological challenges has been reported in patients with panic disorder. We have previously validated transgenic mice overexpressing the…”
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Adaptation of N-methyl-D-aspartate (NMDA) receptors following antidepressant treatment: implications for the pharmacotherapy of depression
Published in Pharmacopsychiatry (01-01-1996)“…NMDA antagonists mimic the effects of clinically effective antidepressants in both preclinical tests predictive of antidepressant action and procedures…”
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Overexpression of Neuronal Pentraxin 1 Is Involved in Neuronal Death Evoked by Low K+ in Cerebellar Granule Cells
Published in The Journal of biological chemistry (05-01-2001)“…Mature cerebellar granule cells in culture die by a process that requires new RNA and protein synthesis when deprived of depolarizing concentrations of…”
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213 NEURONAL PENTRAXIN 1 CONTRIBUTES TO THE DESCENDING MODULATION OF NEUROPATHIC PAIN
Published in European journal of pain (01-09-2009)Get full text
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Adaptive changes in the N-methyl-D-aspartate receptor complex after chronic treatment with imipramine and 1-aminocyclopropanecarboxylic acid
Published in The Journal of pharmacology and experimental therapeutics (01-06-1993)“…Chronic (14 daily injections) treatment of mice with the prototypic tricyclic antidepressant imipramine significantly alters ligand binding to the…”
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Glycine(B) receptor antagonists and partial agonists prevent memory deficits in inhibitory avoidance learning
Published in Neurobiology of learning and memory (01-09-2000)“…Activation of N-methyl-d-aspartate (NMDA) receptors has been hypothesized to mediate certain forms of learning and memory. This hypothesis is based on the…”
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Glycogen synthase kinase-3 is involved in the regulation of the cell cycle in cerebellar granule cells
Published in Neuropharmacology (01-08-2007)“…Recent studies have demonstrated that neuronal reentry in the cell cycle and specifically the expression of the transcription factor E2F-1, constitutes a…”
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Influence of aging on thromboxane A2 and prostacyclin levels in rat hippocampal brain slices
Published in Neurobiology of aging (01-11-1999)“…We have investigated the influence of age (3, 18, 24 months) on Thromboxane A2 (TXA2) and Prostacyclin (PGI2) levels in hippocampal slices from F344/NHSD rats…”
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Differential effects of compounds that act at strychnine-insensitive glycine receptors in a punishment procedure
Published in The Journal of pharmacology and experimental therapeutics (01-08-1994)“…The anxiolytic and memory-impairing effects of compounds that act at strychnine-insensitive (SI) glycine receptors were examined and compared with those of a…”
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Glycine site antagonists and partial agonists inhibit N-methyl-D-aspartate receptor-mediated [3H]arachidonic acid release in cerebellar granule cells
Published in The Journal of pharmacology and experimental therapeutics (01-05-1998)“…Activation of N-methyl-D-aspartate (NMDA) receptors is known to produce arachidonic acid release, which has been implicated in excitotoxicity. Antagonists and…”
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GlycineB Receptor Antagonists and Partial Agonists Prevent Memory Deficits in Inhibitory Avoidance Learning
Published in Neurobiology of learning and memory (01-09-2000)“…Activation of N-methyl-d-aspartate (NMDA) receptors has been hypothesized to mediate certain forms of learning and memory. This hypothesis is based on the…”
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Inhibition of phosphatidylcholine synthesis is associated with excitotoxic cell death in cerebellar granule cell cultures
Published in Amino acids (01-01-2002)“…Glucose deprivation (GD) enhances the sensitivity of cerebellar granule cells to die by excitotoxicity. Neither 70 min of GD, a treatment that depletes cell…”
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Protection by Imidazol(ine) Compounds of l-Glutamate Neurotoxicity Through NMDA Receptor Blockade
Published in Annals of the New York Academy of Sciences (01-06-1999)Get full text
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Cerebrospinal fluid mtDNA concentration is elevated in multiple sclerosis disease and responds to treatment
Published in Multiple sclerosis (01-04-2018)“…Background: Mitochondrial dysfunction is increasingly recognized as an important feature of multiple sclerosis (MS) pathology and may be relevant for clinical…”
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Serial cfDNA analysis for bladder cancer patients monitoring after radical cystectomy: Prognostic significance
Published in European urology open science (Online) (01-10-2022)Get full text
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1-Aminocyclopropane-carboxylic acid reduces NMDA-induced hippocampal neurodegeneration in vivo
Published in Neuroreport (31-01-1996)“…The effect of systemic treatment with 1-aminocyclopro-panecarboxylic acid (ACPC), a partial agonist at the glycine site of the NMDA receptor, on convulsions…”
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Environmentally-induced modification of the benzodiazepine/GABA receptor coupled chloride ionophore
Published in Psychopharmacologia (01-01-1987)“…The benzodiazepine/GABA receptor coupled chloride ionophore was examined in brain membranes of rats maintained in either a conventional animal facility or a…”
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