Search Results - "Truesdell, Samuel S"

A Specialized Mechanism of Translation Mediated by FXR1a-Associated MicroRNP in Cellular Quiescence by Bukhari, Syed I.A., Truesdell, Samuel S., Lee, Sooncheol, Kollu, Swapna, Classon, Anthony, Boukhali, Myriam, Jain, Esha, Mortensen, Richard D., Yanagiya, Akiko, Sadreyev, Ruslan I., Haas, Wilhelm, Vasudevan, Shobha

“…MicroRNAs predominantly decrease gene expression; however, specific mRNAs are translationally upregulated in quiescent (G0) mammalian cells and immature…”
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A post-transcriptional program of chemoresistance by AU-rich elements and TTP in quiescent leukemic cells by Lee, Sooncheol, Micalizzi, Douglas, Truesdell, Samuel S, Bukhari, Syed I A, Boukhali, Myriam, Lombardi-Story, Jennifer, Kato, Yasutaka, Choo, Min-Kyung, Dey-Guha, Ipsita, Ji, Fei, Nicholson, Benjamin T, Myers, David T, Lee, Dongjun, Mazzola, Maria A, Raheja, Radhika, Langenbucher, Adam, Haradhvala, Nicholas J, Lawrence, Michael S, Gandhi, Roopali, Tiedje, Christopher, Diaz-Muñoz, Manuel D, Sweetser, David A, Sadreyev, Ruslan, Sykes, David, Haas, Wilhelm, Haber, Daniel A, Maheswaran, Shyamala, Vasudevan, Shobha

“…Quiescence (G0) is a transient, cell cycle-arrested state. By entering G0, cancer cells survive unfavorable conditions such as chemotherapy and cause relapse…”
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Upregulation of eIF5B controls cell-cycle arrest and specific developmental stages by Lee, Sooncheol, Truesdell, Samuel S, Bukhari, Syed I A, Lee, Ju Huck, LeTonqueze, Olivier, Vasudevan, Shobha

“…Proliferation arrest and distinct developmental stages alter and decrease general translation yet maintain ongoing translation. The factors that support…”
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m5C modification of mRNA serves a DNA damage code to promote homologous recombination by Chen, Hao, Yang, Haibo, Zhu, Xiaolan, Yadav, Tribhuwan, Ouyang, Jian, Truesdell, Samuel S., Tan, Jun, Wang, Yumin, Duan, Meihan, Wei, Leizhen, Zou, Lee, Levine, Arthur S., Vasudevan, Shobha, Lan, Li

“…Recruitment of DNA repair proteins to DNA damage sites is a critical step for DNA repair. Post-translational modifications of proteins at DNA damage sites…”
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Analysis of MicroRNA-Mediated Translation Activation of In Vitro Transcribed Reporters in Quiescent Cells by Bukhari, Syed I A, Truesdell, Samuel S, Vasudevan, Shobha

“…Quiescence (G0) is defined as an assortment of cell cycle arrested states that exhibit distinct properties. Leukemias harbor a subpopulation of G0 cells that…”
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Ribosome changes reprogram translation for chemosurvival in G0 leukemic cells by Datta, Chandreyee, Truesdell, Samuel S, Wu, Keith Q, Bukhari, Syed I A, Ngue, Harrison, Buchanan, Brienna, Le Tonqueze, Olivier, Lee, Sooncheol, Kollu, Swapna, Granovetter, Madeleine A, Boukhali, Myriam, Kreuzer, Johannes, Batool, Maheen S, Balaj, Leonora, Haas, Wilhelm, Vasudevan, Shobha

“…Quiescent leukemic cells survive chemotherapy, with translation changes. Our data reveal that FXR1, a protein amplified in several aggressive cancers, is…”
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Abstract B32: A specialized post-transcriptional program in chemoresistant, quiescent cancer cells by Lee, Sooncheol, Bukhari, Syed I.A., Truesdell, Samuel S., Kollu, Swapna, Mortensen, Richard D., Boukhali, Myriam, Jain, Esha, Lee, Dongjun, Mazzola, Maria, Raheja, Radhika, Langenbucher, Adam, Haradhwala, Nicholas, Yanagiya, Akiko, Lawrence, Michael, Gandhi, Roopali, Sadreyev, Ruslan, Sweetser, David, Haas, Wilhelm, Vasudevan, Shobha

“…Abstract Quiescent (G0) cells are a clinically relevant fraction in cancers, which include dormant cancer stem cells, and resist clinical therapy. G0 cells…”
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Abstract 4997: Specialized microRNP and translation mechanisms in quiescent cancer cells by Bukhari, Syed I., Truesdell, Samuel S., Lee, Sooncheol, Kollu, Swapna, Classon, Anthony, Boukhali, Myriam, Jain, Esha, Mortensen, Richard D., Yanagiya, Akiko, Sadreyev, Ruslan, Haas, Wilhelm, Vasudevan, Shobha

“…Abstract Quiescence (G0) represents an assortment of reversible, cell cycle-arrested states that are resistant to unfavorable conditions and associated with…”
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Abstract 4443: A post-transcriptional program of chemoresistance regulators in quiescent cancer cells by Lee, Sooncheol, Truesdell, Samuel S., Bukhari, Syed I., Boukhali, Myriam, Lee, Dongjun, Mazzola, Maria A., Raheja, Radhika, Langenbucher, Adam, Haradhvala, Nicholas J., Lawrence, Michael, Gandhi, Roopali, Sweetser, David A., Haas, Wilhelm, Vasudevan, Shobha

“…Abstract Quiescent (G0) cells are a clinically relevant fraction in several cancers, which include dormant cancer stem cells, and resist clinical therapy. G0…”
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Upregulation of elF5B controls cell-cycle arrest and specific developmental stages by Lee, Sooncheol, Truesdell, Samuel S., Bukhari, Syed I. A., Lee, Ju Huck, LeTonqueze, Olivier, Vasudevan, Shobha

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m 5 C modification of mRNA serves a DNA damage code to promote homologous recombination by Chen, Hao, Yang, Haibo, Zhu, Xiaolan, Yadav, Tribhuwan, Ouyang, Jian, Truesdell, Samuel S, Tan, Jun, Wang, Yumin, Duan, Meihan, Wei, Leizhen, Zou, Lee, Levine, Arthur S, Vasudevan, Shobha, Lan, Li

“…Recruitment of DNA repair proteins to DNA damage sites is a critical step for DNA repair. Post-translational modifications of proteins at DNA damage sites…”
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