Search Results - "Truedsson, L."

Molecular basis of hereditary C1q deficiency-revisited: identification of several novel disease-causing mutations by Schejbel, L, Skattum, L, Hagelberg, S, Åhlin, A, Schiller, B, Berg, S, Genel, F, Truedsson, L, Garred, P

“…C1q is the central pattern-recognition molecule in the classical pathway of the complement system and is known to have a key role in the crossroads between…”
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Complement classical pathway components are all important in clearance of apoptotic and secondary necrotic cells by Gullstrand, B, Mårtensson, U, Sturfelt, G, Bengtsson, A.A, Truedsson, L

“…Inherited deficiencies in components of the classical complement pathway are strong disease susceptibility factors for the development of systemic lupus…”
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Influence of methotrexate, TNF blockers and prednisolone on antibody responses to pneumococcal polysaccharide vaccine in patients with rheumatoid arthritis by Kapetanovic, M. C., Saxne, T., Sjöholm, A., Truedsson, L., Jönsson, G., Geborek, P.

“…Objective. To compare antibody responses to 23-valent pneumococcal vaccine (Pneumovax®) in controls and patients with established rheumatoid arthritis (RA)…”
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Genetic association of miRNA-146a with systemic lupus erythematosus in Europeans through decreased expression of the gene by Löfgren, S E, Frostegård, J, Truedsson, L, Pons-Estel, B A, D'Alfonso, S, Witte, T, Lauwerys, B R, Endreffy, E, Kovács, L, Vasconcelos, C, Martins da Silva, B, Kozyrev, S V, Alarcón-Riquelme, M E

“…A recent genome-wide association study revealed a variant (rs2431697) in an intergenic region, between the pituitary tumor-transforming 1 ( PTTG1 ) and…”
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Increased C1q, C4 and C3 deposition on platelets in patients with systemic lupus erythematosus – a possible link to venous thrombosis? by Lood, C, Eriksson, S, Gullstrand, B, Jönsen, A, Sturfelt, G, Truedsson, L, Bengtsson, AA

“…Objective: Patients with systemic lupus erythematosus (SLE) have an increased risk of developing vascular diseases (VD) such as myocardial infarction, stroke…”
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Additive effects of the major risk alleles of IRF5 and STAT4 in primary Sjögren's syndrome by Nordmark, G, Kristjansdottir, G, Theander, E, Eriksson, P, Brun, J G, Wang, C, Padyukov, L, Truedsson, L, Alm, G, Eloranta, M-L, Jonsson, R, Rönnblom, L, Syvänen, A-C

“…Primary Sjögren's syndrome (SS) shares many features with systemic lupus erythematosus (SLE). Here we investigated the association of the three major…”
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Complement and its breakdown products in SLE by Sturfelt, G., Truedsson, L.

“…The complement system has important protective functions in both the innate and the adaptive immune systems but can also, when inappropriately activated, cause…”
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Rheumatological manifestations, organ damage and autoimmunity in hereditary C2 deficiency by Jönsson, G., Sjöholm, A. G., Truedsson, L., Bengtsson, A. A., Braconier, J. H., Sturfelt, G.

“…Objective. To analyse rheumatological manifestations, organ damage and autoimmune responses in a large cohort of patients (n = 45) with homozygous C2…”
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Systemic lupus erythematosus subgroups, with features of antiphospholipid or Sjogren's syndrome, differ in molecular signatures and treatment perspectives by Idborg, H., Zandian, Arash, Sandberg, A., Truedsson, L., Nilsson, B., Elvin, K., Mo, J., Gustafsson, J., Gunnarsson, I., Lehtio, J., Nilsson, P., Svenungsson, E., Jakobsson, P.

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CD81 and CD48 show different expression on blood eosinophils in systemic sclerosis: new markers for disease and pulmonary inflammation? by Wuttge, DM, Andreasson, A, Tufvesson, E, Johansson, ÅCM, Scheja, A, Hellmark, T, Hesselstrand, R, Truedsson, L

“…Objectives: In systemic sclerosis (SSc)-related interstitial lung disease (ILD), elevated eosinophil counts in bronchoalveolar lavage are associated with a…”
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Activation of type I interferon system in systemic lupus erythematosus correlates with disease activity but not with antiretroviral antibodies by Bengtsson, A A, Sturfelt, G, Truedsson, L, Blomberg, J, Alm, G, Vallin, H, Rönnblom, L

“…The objective was to investigate the relation between serum levels of interferon-α (IFN-α), the activity of an endogenous IFN-a inducing factor (SLE-IIF),…”
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Complement deficiency and disease: An update by Sjöholm, A.G., Jönsson, G., Braconier, J.H., Sturfelt, G., Truedsson, L.

“…Complement deficiencies are probably vastly under-diagnosed within clinical medicine. Judging from a Swedish study of C2 deficiency, a deficiency with an…”
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Heat differentiated complement factor profiling by Hamsten, Carl, Skattum, Lillemor, Truedsson, Lennart, von Döbeln, Ulrika, Uhlén, Mathias, Schwenk, Jochen M., Hammarström, Lennart, Nilsson, Peter, Neiman, Maja

“…Complement components and their cascade of reactions are important defense mechanisms within both innate and adaptive immunity. Many complement deficient…”
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Contribution of IKBKE and IFIH1 gene variants to SLE susceptibility by Wang, C, Ahlford, A, Laxman, N, Nordmark, G, Eloranta, M-L, Gunnarsson, I, Svenungsson, E, Padyukov, L, Sturfelt, G, Jönsen, A, Bengtsson, A A, Truedsson, L, Rantapää-Dahlqvist, S, Sjöwall, C, Sandling, J K, Rönnblom, L, Syvänen, A-C

“…The type I interferon system genes IKBKE and IFIH1 are associated with the risk of systemic lupus erythematosus (SLE). To identify the sequence variants that…”
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Evaluation of Reversal of IGAD: Relevance for the Diagnosis in Children by Lim, C., Dahle, C., Elvin, K., Andersson, B., Rönnelid, Johan, Truedsson, L., Hammarstrom, L.

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Low diagnostic and predictive value of anti-dsDNA antibodies in unselected patients with recent onset of rheumatic symptoms: results from a long-term follow-up Scandinavian multicentre study by Compagno, M, Jacobsen, S, Rekvig, OP, Truedsson, L, Heegaard, NH, Nossent, J, Jönsen, A, Jacobsen, RS, Eilertsen, GØ, Sturfelt, G, Bengtsson1, AA

“…Objectives: To verify the diagnostic accuracy of anti-double-stranded DNA (anti-dsDNA) antibodies detected by the Crithidia luciliae immunofluorescence test…”
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Association between SLE nephritis and polymorphic variants of the CRP and FcγRIIIa genes by Jönsen, A., Gunnarsson, I., Gullstrand, B., Svenungsson, E., Bengtsson, A. A., Nived, O., Lundberg, I. E., Truedsson, L., Sturfelt, G.

“…Objectives. To study the relationship between clinical manifestations in systemic lupus erythematosus (SLE) with polymorphisms in suggested susceptibility…”
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Increased serum type I interferon activity in early systemic sclerosis patients is associated with antibodies against Sjögren's syndrome antigens and nuclear ribonucleoprotein antigens by Wuttge, DM, Lood, C, Tufvesson, E, Scheja, A, Truedsson, L, Bengtsson, AA, Hesselstrand, R

“…Objective: To study serum type I interferon (IFN) activity in patients with early systemic sclerosis (SSc). Method: Serum type I IFN activity was measured in…”
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The Inflammatory Response and its Consequence for the Clinical Outcome Following Aortic Aneurysm Repair by Swartbol, P., Truedsson, L., Norgren, L.

“…Objective to review published studies on the outcome of the inflammatory response after abdominal aortic aneurysm (AAA) repair. Methods a literature search on…”
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Deficiency of the mannan‐binding lectin pathway of complement and poor outcome in cystic fibrosis: bacterial colonization may be decisive for a relationship by Carlsson, M., Sjöholm, A. G., Eriksson, L., Thiel, S., Jensenius, J. C., Segelmark, M., Truedsson, L.

“…Summary In cystic fibrosis (CF) prognosis concerning lung damage development is highly variable and difficult to predict. Mannan‐binding lectin (MBL)…”
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