Search Results - "Trudel, Guy"
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1
Hemolysis contributes to anemia during long-duration space flight
Published in Nature medicine (01-01-2022)“…Anemia in astronauts has been noted since the first space missions, but the mechanisms contributing to anemia in space flight have remained unclear. Here, we…”
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2
Characterizing the effect of exposure to microgravity on anemia: more space is worse
Published in American journal of hematology (01-03-2020)“…The effects of space travel have renewed importance with space tourism and plans for long‐term missions to the moon and Mars. The study of space anemia is…”
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3
Bone marrow adiposity modulation after long duration spaceflight in astronauts
Published in Nature communications (09-08-2023)“…Space travel requires metabolic adaptations from multiple systems. While vital to bone and blood production, human bone marrow adipose (BMA) tissue modulation…”
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4
The transcriptome response of astronaut leukocytes to long missions aboard the International Space Station reveals immune modulation
Published in Frontiers in immunology (22-06-2023)“…Spaceflight leads to the deconditioning of multiple body systems including the immune system. We sought to characterize the molecular response involved by…”
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Noninflammatory Joint Contractures Arising from Immobility: Animal Models to Future Treatments
Published in BioMed research international (01-01-2015)“…Joint contractures, defined as the limitation in the passive range of motion of a mobile joint, can be classified as noninflammatory diseases of the…”
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Quantitative and temporal differential recovery of articular and muscular limitations of knee joint contractures; results in a rat model
Published in Journal of applied physiology (1985) (01-10-2014)“…Joint contractures alter the mechanical properties of articular and muscular structures. Reversibility of a contracture depends on the restoration of the…”
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7
Can eating pleasure be a lever for healthy eating? A systematic scoping review of eating pleasure and its links with dietary behaviors and health
Published in PloS one (21-12-2020)“…The aims of this review were to map and summarize data currently available about 1) key dimensions of eating pleasure; 2) associations of eating pleasure, and…”
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8
Protecting the regenerative environment: selecting the optimal delivery vehicle for cartilage repair-a narrative review
Published in Frontiers in bioengineering and biotechnology (2024)“…Focal cartilage defects are common in youth and older adults, cause significant morbidity and constitute a major risk factor for developing osteoarthritis…”
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Reversibility of marrow adipose accumulation and reduction of trabecular bone in the epiphysis of the proximal tibia
Published in Acta histochemica (01-10-2020)“…Mechanical stimuli play an important role in the homeostasis of trabecular bone and marrow adipose tissue, particularly for the weight-bearing skeleton…”
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10
Spatiotemporal expression and control of haemoglobin in space
Published in Nature communications (11-06-2024)“…It is now widely recognised that the environment in space activates a diverse set of genes involved in regulating fundamental cellular pathways. This includes…”
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11
Transcriptomic evidence of erythropoietic adaptation from the International Space Station and from an Earth-based space analog
Published in NPJ microgravity (13-05-2024)“…Space anemia affects astronauts and the underlying molecular alterations remain unknown. We evaluated the response of erythropoiesis-modulating genes to…”
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12
Adaptation and Validation of the Well-Being Related to Food Questionnaire (Well-BFQ©) for the French-Speaking General Adult Population of Québec, Canada
Published in Nutrients (23-02-2023)“…Efforts to develop effective strategies that improve dietary intake are needed; however, this improvement in diet quality must not be at the expense of…”
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13
Towards data-driven biopsychosocial classification of non-specific chronic low back pain: a pilot study
Published in Scientific reports (12-08-2023)“…The classification of non-specific chronic low back pain (CLBP) according to multidimensional data could guide clinical management; yet recent systematic…”
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14
Evidence- and data-driven classification of low back pain via artificial intelligence: Protocol of the PREDICT-LBP study
Published in PloS one (21-08-2023)“…In patients presenting with low back pain (LBP), once specific causes are excluded (fracture, infection, inflammatory arthritis, cancer, cauda equina and…”
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15
Intra-articular collagenase injection increases range of motion in a rat knee flexion contracture model
Published in Drug design, development and therapy (01-01-2018)“…A knee joint contracture, a loss in passive range of motion (ROM), can be caused by prolonged immobility. In a rat knee immobilization flexion contracture…”
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Knee Flexion Contractures in Patients with Osteoarthritis: Clinical Features and Histologic Characterization of the Posterior Capsule
Published in PM & R (01-05-2015)“…Abstract Objective To (1) identify demographic and clinical factors associated with knee flexion contracture (KFlC) in the setting of osteoarthritis (OA) and…”
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17
Supraspinatus tendon transosseous vs anchor repair surgery: a comparative study of mechanical recovery in the rabbit
Published in Journal of orthopaedic surgery and research (07-12-2020)“…Abstract Background Supraspinatus (SSP) tendon ruptures requiring surgical repair are common. Arthroscopic suture anchor fixation has gradually replaced…”
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18
Six degrees head-down tilt bed rest caused low-grade hemolysis: a prospective randomized clinical trial
Published in NPJ microgravity (15-02-2021)“…This study aimed to measure hemolysis before, during and after 60 days of the ground-based spaceflight analog bed rest and the effect of a nutritional…”
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19
Temporal gene expression profiling of the rat knee joint capsule during immobilization-induced joint contractures
Published in BMC musculoskeletal disorders (26-05-2015)“…Contractures of the knee joint cause disability and handicap. Recovering range of motion is recognized by arthritic patients as their preference for improved…”
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20
Joint contracture following prolonged stay in the intensive care unit
Published in Canadian Medical Association journal (CMAJ) (11-03-2008)“…Prolonged immobility during a critical illness may predispose patients to the development of joint contracture. We sought to document the incidence of, the…”
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