Search Results - "Truchon, G"

Effects of inhaled nano-TiO2 aerosols showing two distinct agglomeration states on rat lungs by Noël, A., Maghni, K., Cloutier, Y., Dion, C., Wilkinson, K.J., Hallé, S., Tardif, R., Truchon, G.

“…► We compare the relative pulmonary toxicity induced by aerosolized nano-TiO2 (5nm). ► Rats inhaled small (<100nm) or large agglomerates (>100nm) at 2 and…”
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Mass or total surface area with aerosol size distribution as exposure metrics for inflammatory, cytotoxic and oxidative lung responses in rats exposed to titanium dioxide nanoparticles by Noël, A, Truchon, G, Cloutier, Y, Charbonneau, M, Maghni, K, Tardif, R

“…There is currently no consensus on the best exposure metric(s) for expressing nanoparticle (NP) dose. Although surface area has been extensively studied for…”
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A weight of evidence approach for the assessment of the ototoxic potential of industrial chemicals by Vyskocil, A, Truchon, G, Leroux, T, Lemay, F, Gendron, M, Gagnon, F, Majidi, N El, Boudjerida, A, Lim, S, Emond, C, Viau, C

“…There is accumulating epidemiological evidence that exposure to some solvents, metals, asphyxiants and other substances in humans is associated with an…”
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Impact of emerging pollutants on pulmonary inflammation in asthmatic rats: ethanol vapors and agglomerated TiO2 nanoparticles by Scarino, A., Noël, A., Renzi, P. M., Cloutier, Y., Vincent, R., Truchon, G., Tardif, R., Charbonneau, M.

“…Context: Titanium dioxide nanoparticles (nano-TiO2) and ethanol vapors are air contaminants with increasing importance. The presence of a pathological…”
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Evaluation of occupational exposure: comparison of biological and environmental variabilities using physiologically based toxicokinetic modeling by Truchon, G., Tardif, R., Charest-Tardif, G., de Batz, A., Droz, P. O.

“…Purpose Few studies compare the variabilities that characterize environmental (EM) and biological monitoring (BM) data. Indeed, comparing their respective…”
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Ototoxicity of trichloroethylene in concentrations relevant for the working environment by Vyskocil, A, Leroux, T, Truchon, G, Lemay, F, Gagnon, F, Gendron, M, Viau, C

“…Organic solvents can cause hearing loss themselves or promote noise-induced hearing loss. The objective of this study was to review the literature on the…”
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Occupational ototoxicity of n-hexane by Vyskocil, A, Leroux, T, Truchon, G, Gendron, M, El Majidi, N, Viau, C

“…The ability of chemicals to produce hearing loss themselves or to promote noise-induced hearing loss has been reported for some organic solvents. The objective…”
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Comparison of unchanged n-hexane in alveolar air and 2,5-hexanedione in urine for the biological monitoring of n-hexane exposure in human volunteers by HAMELIN, G, TRUCHON, G, TARDIF, R

“…Biological monitoring of n-hexane (HEX) is based on the measurement of urinary 2,5-hexanedione (2,5-HD). In 2001, the American Conference of Governmental…”
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Impact of Biological and Environmental Variabilities on Biological Monitoring-An Approach Using Toxicokinetic Models by Berthet, A., de Batz, A., Tardif, R., Charest-Tardif, G., Truchon, G., Vernez, D., Droz, P. O.

“…Biological monitoring of occupational exposure is characterized by important variability, due both to variability in the environment and to biological…”
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Ethyl benzene should be considered ototoxic at occupationally relevant exposure concentrations by Vyskocil, A, Leroux, T, Truchon, G, Lemay, F, Gendron, M, Gagnon, F, El Majidi, N, Viau, C

“…Organic solvents can produce ototoxic effects in both man and experimental animals. The objective of this study was to review the literature on the effects of…”
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Physiologically Based Modeling of n-Hexane Kinetics in Humans Following Inhalation Exposure at Rest and Under Physical Exertion: Impact on Free 2,5-Hexanedione in Urine and on n-Hexane in Alveolar Air by Hamelin, G., Charest-Tardif, G., Truchon, G., Tardif, R.

“…We used a modified physiologically based pharmacokinetic (PBPK) to describe/predict n-hexane (HEX) alveolar air concentrations and free 2,5-HD urinary…”
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Visual Dysfunction among styrene-exposed Workers by Campagna, Dave, Mergler, Donna, Huel, Guy, Bélanger, Suzanne, Truchon, Ginette, Ostiguy, Claude, Drolet, Daniel

“…Objectives The present study was undertaken to examine the relation between visual functions and occupational exposure to styrene. Methods A total of 128…”
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Gas Chromatographic Determination of Urinary o-Cresol for the Monitoring of Toluene Exposure by Truchon, G., Tardif, R., Brodeur, J.

“…A sensitive and reproducible gas chromatographic procedure for the quantitative determination of urinary o-cresol is described. The first step involves acid…”
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Surveillance of early neurotoxic dysfunction by Mergler, D, Huel, G, Bélanger, S, Bowler, R M, Truchon, G, Drolet, D, Ostiguy, C

“…Surveillance of early neurotoxic alterations was undertaken in 3 reinforced plastics plants, with a view to preventive intervention. Using a longitudinal study…”
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Presence of N-nitrosodiethanolamine contamination in Canadian metal-working fluids by Fadlallah, S., Cooper, S.F., Perrault, G., Truchon, G., Lesage, J.

“…N-Nitroso compounds are notorious mutagens, carcinogens and teratogens that can be seriously hazardous to human health. Metal-working fluids (MWFs) are used…”
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Simultaneous determination of urinary mandelic, phenylglyoxylic, and mercapturic acids of styrene by high-performance liquid chromatography by Truchon, G, Brodeur, J, Gérin, M

“…We have developed a relatively simple and reproducible HPLC procedure for the determination of urinary metabolites of styrene. Urine samples (pH 2) are…”
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Pilot study of peripheral markers of catecholaminergic systems among workers occupationally exposed to toluene by Smargiassi, A, Mutti, A, Bergamaschi, E, Bélanger, S, Truchon, G, Mergler, D

“…In a pilot study, serum dopamine beta-hydroxylase (DBH), platelets monoamine oxidase type B (MAO B) activities and basal plasma prolactin (PRL) were measured,…”
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N-Nitroso compounds in the ambient air of metal factories using metal-working fluids by FADLALLAH, S, COOPER, S. F, PERRAULT, G, TRUCHON, G, LESAGE, J

“…Metal-working fluids are used for lubricating and cooling the cutting and grinding surfaces of metals in metallurgical industries. N-nitrosodiethanolamine, a…”
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Kidney function in male and female rats chronically exposed to potassium dichromate by Vyskocil, A, Viau, C, Cízková, M, Truchon, G

“…Male and female Wistar rats were given 25 mg l-1 chromium (as potassium dichromate) in drinking water for 6 months. Lactate dehydrogenase, lysozyme, total…”
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Modeling the impact of workload intensity on the biological exposure indicators of solvents by Tardif, R., Truchon, G., Bérubé, A., Sari-Minodier, I., Charest-Tardif, G.

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