Search Results - "Trucco, M"
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Axitinib plus pembrolizumab in patients with advanced sarcomas including alveolar soft-part sarcoma: a single-centre, single-arm, phase 2 trial
Published in The lancet oncology (01-06-2019)“…VEGF promotes an immunosuppressive microenvironment and contributes to immune checkpoint inhibitor resistance in cancer. We aimed to assess the activity of the…”
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2
Polygenic risk prediction based on singular value decomposition with applications to alcohol use disorder
Published in BMC bioinformatics (10-01-2022)“…The polygenic risk score (PRS) shows promise as a potentially effective approach to summarize genetic risk for complex diseases such as alcohol use disorder…”
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3
Pig‐to‐Monkey Islet Xenotransplantation Using Multi‐Transgenic Pigs
Published in American journal of transplantation (01-10-2014)“…The generation of pigs with genetic modifications has significantly advanced the field of xenotransplantation. New genetically engineered pigs were produced on…”
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4
Retinoic acid‐producing, ex‐vivo‐generated human tolerogenic dendritic cells induce the proliferation of immunosuppressive B lymphocytes
Published in Clinical and experimental immunology (01-11-2013)“…Summary While much is known about tolerogenic dendritic cell effects on forkhead box protein 3 (FoxP3)+ regulatory T cells, virtually nothing is known about…”
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5
Islet Amyloid Deposition Limits the Viability of Human Islet Grafts but Not Porcine Islet Grafts
Published in Proceedings of the National Academy of Sciences - PNAS (02-03-2010)“…Islet transplantation is a promising treatment for diabetes but longterm success is limited by progressive graft loss. Aggregates of the beta cell peptide…”
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6
Childhood adversity, externalizing behavior, and substance use in adolescence: Mediating effects of anterior cingulate cortex activation during inhibitory errors
Published in Development and psychopathology (01-10-2019)“…Childhood adversity can negatively impact development across various domains, including physical and mental health. Adverse childhood experiences have been…”
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7
C-peptide reduces high-glucose-induced apoptosis of endothelial cells and decreases NAD(P)H-oxidase reactive oxygen species generation in human aortic endothelial cells
Published in Diabetologia (01-10-2011)“…Aims/hypothesis Reactive oxygen species (ROS) generated during hyperglycaemia are implicated in the development of diabetic vascular complications. High…”
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8
A review of psychosocial factors linked to adolescent substance use
Published in Pharmacology, biochemistry and behavior (01-09-2020)“…Informed by ecological theories and models of influence, this review discusses various psychosocial risk and protective factors that contribute to adolescent…”
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9
Use of Intravenous Gamma Globulin and Corticosteroids in the Treatment of Maternal Autoantibody-Mediated Cardiomyopathy
Published in Journal of the American College of Cardiology (08-02-2011)“…Objectives This study sought to evaluate the outcome of maternal autoantibody-mediated fetal cardiomyopathy/endocardial fibroelastosis following intravenous…”
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10
Improved Quality of Life Following Total Pancreatectomy and Auto-islet Transplantation for Chronic Pancreatitis
Published in Journal of gastrointestinal surgery (01-08-2012)“…Background Total pancreatectomy (TP) with auto-islet transplant (AIT) is an extreme treatment for chronic pancreatitis, and we reviewed our experience to…”
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11
The Future of Islet Transplantation Is Now
Published in Frontiers in medicine (13-07-2018)“…Milestones in the history of diabetes therapy include the discovery of insulin and successful methods of beta cell replacement including whole pancreas and…”
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12
Distress tolerance and emotional regulation in individuals with alcohol use disorder
Published in Frontiers in psychiatry (12-05-2023)“…Previous research suggests that low distress tolerance may be associated with poor emotion regulation, contribute to drinking to cope motives, and predict…”
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13
Radiation Dose Benchmarks During Cardiac Catheterization for Congenital Heart Disease in the United States
Published in JACC. Cardiovascular interventions (01-09-2014)“…Abstract Objectives The aim of this study was to define age-stratified, procedure-specific benchmark radiation dose levels during interventional…”
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14
First-generation genetic drift and inbreeding risk in hatchery stocks of the wreckfish Polyprion americanus
Published in Aquaculture (20-01-2016)“…The wreckfish Polyprion americanus is a component of directed and admixed species fisheries throughout its world range and has recently been identified for its…”
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15
Susceptibility effects of GABA receptor subunit alpha-2 (GABRA2) variants and parental monitoring on externalizing behavior trajectories: Risk and protection conveyed by the minor allele
Published in Development and psychopathology (01-02-2016)“…Understanding factors increasing susceptibility to social contexts and predicting psychopathology can help identify targets for prevention. Persistently high…”
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Long‐Term Controlled Normoglycemia in Diabetic Non‐Human Primates After Transplantation with hCD46 Transgenic Porcine Islets
Published in American journal of transplantation (01-12-2009)“…Xenotransplantation of porcine islets into diabetic non‐human primates is characterized by (i) an initial massive graft loss possibly due to the instant…”
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17
Alcohol use and interoception – A narrative review
Published in Progress in neuro-psychopharmacology & biological psychiatry (20-12-2021)“…Interoception, defined as the ability to perceive and interpret body signals, may play an important role in alcohol use disorder (AUD). Earlier studies…”
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18
Current and future targeted alpha particle therapies for osteosarcoma: Radium-223, actinium-225, and thorium-227
Published in Frontiers in medicine (15-11-2022)“…Osteosarcoma is a high-grade sarcoma characterized by osteoid formation, nearly universal expression of IGF1R and with a subset expressing HER-2. These…”
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Childhood Trauma, Emotion Regulation, and Pain in Individuals With Alcohol Use Disorder
Published in Frontiers in psychiatry (30-10-2020)“…Introduction: Several studies have confirmed that the experience of childhood trauma, poor emotion regulation, as well as the experience of physical pain may…”
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Early adolescent alcohol use in context: how neighborhoods, parents, and peers impact youth
Published in Development and psychopathology (01-05-2014)“…Developmental-ecological models are useful for integrating risk factors across multiple contexts and conceptualizing mediational pathways for adolescent…”
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