Search Results - "Truban, Dominika"

PINK1, Parkin, and Mitochondrial Quality Control: What can we Learn about Parkinson's Disease Pathobiology? by Truban, Dominika, Hou, Xu, Caulfield, Thomas R, Fiesel, Fabienne C, Springer, Wolfdieter

“…The first clinical description of Parkinson's disease (PD) will embrace its two century anniversary in 2017. For the past 30 years, mitochondrial dysfunction…”
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Age- and disease-dependent increase of the mitophagy marker phospho-ubiquitin in normal aging and Lewy body disease by Hou, Xu, Fiesel, Fabienne C., Truban, Dominika, Castanedes Casey, Monica, Lin, Wen-lang, Soto, Alexandra I., Tacik, Pawel, Rousseau, Linda G., Diehl, Nancy N., Heckman, Michael G., Lorenzo-Betancor, Oswaldo, Ferrer, Isidre, Arbelo, José M., Steele, John C., Farrer, Matthew J., Cornejo-Olivas, Mario, Torres, Luis, Mata, Ignacio F., Graff-Radford, Neill R., Wszolek, Zbigniew K., Ross, Owen A., Murray, Melissa E., Dickson, Dennis W., Springer, Wolfdieter

“…Although exact causes of Parkinson disease (PD) remain enigmatic, mitochondrial dysfunction is increasingly appreciated as a key determinant of dopaminergic…”
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Identification of Yeast Mutants Exhibiting Altered Sensitivity to Valinomycin and Nigericin Demonstrate Pleiotropic Effects of Ionophores on Cellular Processes by Jakubkova, Michaela, Dzugasova, Vladimira, Truban, Dominika, Abelovska, Lenka, Bhatia-Kissova, Ingrid, Valachovic, Martin, Klobucnikova, Vlasta, Zeiselova, Lucia, Griac, Peter, Nosek, Jozef, Tomaska, Lubomir

“…Ionophores such as valinomycin and nigericin are potent tools for studying the impact of ion perturbance on cellular functions. To obtain a broader picture…”
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Heterozygous PINK1 p.G411S increases risk of Parkinson's disease via a dominant-negative mechanism by Puschmann, Andreas, Fiesel, Fabienne C, Caulfield, Thomas R, Hudec, Roman, Ando, Maya, Truban, Dominika, Hou, Xu, Ogaki, Kotaro, Heckman, Michael G, James, Elle D, Swanberg, Maria, Jimenez-Ferrer, Itzia, Hansson, Oskar, Opala, Grzegorz, Siuda, Joanna, Boczarska-Jedynak, Magdalena, Friedman, Andrzej, Koziorowski, Dariusz, Rudzińska-Bar, Monika, Aasly, Jan O, Lynch, Timothy, Mellick, George D, Mohan, Megha, Silburn, Peter A, Sanotsky, Yanosh, Vilariño-Güell, Carles, Farrer, Matthew J, Chen, Li, Dawson, Valina L, Dawson, Ted M, Wszolek, Zbigniew K, Ross, Owen A, Springer, Wolfdieter

“…SEE GANDHI AND PLUN-FAVREAU DOI101093/AWW320 FOR A SCIENTIFIC COMMENTARY ON THIS ARTICLE: It has been postulated that heterozygous mutations in recessive…”
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Sensitive ELISA-based detection method for the mitophagy marker p-S65-Ub in human cells, autopsy brain, and blood samples by Watzlawik, Jens O., Hou, Xu, Fricova, Dominika, Ramnarine, Chloe, Barodia, Sandeep K., Gendron, Tania F., Heckman, Michael G., DeTure, Michael, Siuda, Joanna, Wszolek, Zbigniew K., Scherzer, Clemens R., Ross, Owen A., Bu, Guojun, Dickson, Dennis W., Goldberg, Matthew S., Fiesel, Fabienne C., Springer, Wolfdieter

“…Mitochondrial dysfunction is an early, imminent event in neurodegenerative disorders including Parkinson disease (PD) and Alzheimer disease (AD). The enzymatic…”
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Distinct Missense Mutations of the Parkinson's Disease‐Related Ubiquitin Kinase PINK1 Alter Auto‐ or Substrate‐Phosphorylation by Springer, Wolfdieter, Truban, Dominika, Caulfield, Thomas R, Hudec, Roman, Hou, Xu, Lewis‐Tuffin, Laura J, McCarty, Arthur M, Soto, Alexandra I, Walton, Ronald L, Puschmann, Andreas, Wszolek, Zbigniew K, Ross, Owen A, Fiesel, Fabienne C

“…The mitochondrial ubiquitin (Ub) kinase PINK1 and the cytosolic E3 Ub ligase PRKN (Parkin) together mediate the selective degradation of damaged mitochondria…”
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Homology arms of targeting vectors for gene insertions and CRISPR/Cas9 technology: size does not matter; quality control of targeted clones does by Petrezselyova, Silvia, Kinsky, Slavomir, Truban, Dominika, Sedlacek, Radislav, Burtscher, Ingo, Lickert, Heiko

“…Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated 9 (Cas9) technology has brought rapid progress in mammalian genome editing…”
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The structure and DNA-binding properties of Mgm101 from a yeast with a linear mitochondrial genome by Pevala, Vladimír, Truban, Dominika, Bauer, Jacob A, Košťan, Július, Kunová, Nina, Bellová, Jana, Brandstetter, Marlene, Marini, Victoria, Krejčí, Lumír, Tomáška, Ľubomír, Nosek, Jozef, Kutejová, Eva

“…To study the mechanisms involved in the maintenance of a linear mitochondrial genome we investigated the biochemical properties of the recombination protein…”
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Reply: Heterozygous PINK1 p.G411S in rapid eye movement sleep behaviour disorder by Puschmann, Andreas, Fiesel, Fabienne C, Caulfield, Thomas R, Hudec, Roman, Ando, Maya, Truban, Dominika, Hou, Xu, Ogaki, Kotaro, Heckman, Michael G, James, Elle D, Swanberg, Maria, Jimenez-Ferrer, Itzia, Hansson, Oskar, Opala, Grzegorz, Siuda, Joanna, Boczarska-Jedynak, Magdalena, Friedman, Andrzej, Koziorowski, Dariusz, Rudzinska-Bar, Monika, Aasly, Jan O, Lynch, Timothy, Mellick, George D, Mohan, Megha, Silburn, Peter A, Sanotsky, Yanosh, Vilariño-Güell, Carles, Farrer, Matthew J, Chen, Li, Dawson, Valina L, Dawson, Ted M, Wszolek, Zbigniew K, Ross, Owen A, Springer, Wolfdieter

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