Search Results - "Troxell, Bryan"

A type 6 secretion system (T6SS) encoded gene within Salmonella enterica serovar Enteritidis contributes to virulence by Troxell, Bryan

“…Bacteria interact with their host through protein secretion systems and surface structures. Pathogenic bacteria encode protein secretion systems that promote…”
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Transcriptional regulation by Ferric Uptake Regulator (Fur) in pathogenic bacteria by Troxell, Bryan, Hassan, Hosni M

“…In the ancient anaerobic environment, ferrous iron (Fe(2+)) was one of the first metal cofactors. Oxygenation of the ancient world challenged bacteria to…”
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DhhP, a cyclic di-AMP phosphodiesterase of Borrelia burgdorferi, is essential for cell growth and virulence by Ye, Meiping, Zhang, Jun-Jie, Fang, Xin, Lawlis, Gavin B, Troxell, Bryan, Zhou, Yan, Gomelsky, Mark, Lou, Yongliang, Yang, X Frank

“…Cyclic di-AMP (c-di-AMP) is a recently discovered second messenger in bacteria. Most of work on c-di-AMP signaling has been done in Gram-positive bacteria,…”
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The Fur regulon in anaerobically grown Salmonella enterica sv. Typhimurium: identification of new Fur targets by Troxell, Bryan, Fink, Ryan C, Porwollik, Steffen, McClelland, Michael, Hassan, Hosni M

“…The Ferric uptake regulator (Fur) is a transcriptional regulator that controls iron homeostasis in bacteria. Although the regulatory role of Fur in Escherichia…”
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Cyclic di-GMP is essential for the survival of the lyme disease spirochete in ticks by He, Ming, Ouyang, Zhiming, Troxell, Bryan, Xu, Haijun, Moh, Akira, Piesman, Joseph, Norgard, Michael V, Gomelsky, Mark, Yang, X Frank

“…Cyclic dimeric GMP (c-di-GMP) is a bacterial second messenger that modulates many biological processes. Although its role in bacterial pathogenesis during…”
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Manganese and Zinc Regulate Virulence Determinants in Borrelia burgdorferi by Troxell, Bryan, Ye, Meiping, Yang, Youyun, Carrasco, Sebastian E, Lou, Yongliang, Yang, X Frank

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Fur Negatively Regulates hns and Is Required for the Expression of HilA and Virulence in Salmonella enterica Serovar Typhimurium by TROXELL, Bryan, SIKES, Michael L, FINK, Ryan C, VAZQUEZ-TORRES, Andres, JONES-CARSON, Jessica, HASSAN, Hosni M

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Partial genome content within rAAVs impacts performance in a cell assay-dependent manner by Troxell, Bryan, Jaslow, Sarah L., Tsai, I-Wei, Sullivan, Chelsea, Draper, Benjamin E., Jarrold, Martin F., Lindsey, Kate, Blue, Levi

“…Recombinant adeno-associated viruses (rAAVs) deliver DNA to numerous cell types. However, packaging of partial genomes into the rAAV capsid is of concern…”
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Pyruvate protects pathogenic spirochetes from H2O2 killing by Troxell, Bryan, Zhang, Jun-Jie, Bourret, Travis J, Zeng, Melody Yue, Blum, Janice, Gherardini, Frank, Hassan, Hosni M, Yang, X Frank

“…Pathogenic spirochetes cause clinically relevant diseases in humans and animals, such as Lyme disease and leptospirosis. The causative agent of Lyme disease,…”
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Attenuated Salmonella enterica Serovar Typhimurium, Strain NC983, Is Immunogenic, and Protective against Virulent Typhimurium Challenges in Mice by Troxell, Bryan, Mendoza, Mary, Ali, Rizwana, Koci, Matthew, Hassan, Hosni

“…Non-typhoidal (NTS) serovars are significant health burden worldwide. Although much effort has been devoted to developing typhoid-based vaccines for humans,…”
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FNR Is a Global Regulator of Virulence and Anaerobic Metabolism in Salmonella enterica Serovar Typhimurium (ATCC 14028s) by FINK, Ryan C, EVANS, Matthew R, PORWOLLIK, Steffen, VAZQUEZ-TORRES, Andres, JONES-CARSON, Jessica, TROXELL, Bryan, LIBBY, Stephen J, MCCLELLAND, Michael, HASSAN, Hosni M

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Transcriptional responses of Leptospira interrogans to host innate immunity: significant changes in metabolism, oxygen tolerance, and outer membrane by Xue, Feng, Dong, Haiyan, Wu, Jinyu, Wu, Zuowei, Hu, Weilin, Sun, Aihua, Troxell, Bryan, Yang, X Frank, Yan, Jie

“…Leptospira interrogans is the major causative agent of leptospirosis. Phagocytosis plays important roles in the innate immune responses to L. interrogans…”
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Ferric Uptake Regulator-Dependent Antinitrosative Defenses in Salmonella enterica Serovar Typhimurium Pathogenesis by Husain, Maroof, Jones-Carson, Jessica, Liu, Lin, Song, Miryoung, Saah, J Royden, Troxell, Bryan, Mendoza, Mary, Hassan, Hosni, Vázquez-Torres, Andrés

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Salmonella enterica serovar Typhimurium utilizes the ClpPX and Lon proteases for optimal fitness in the ceca of chickens by Troxell, Bryan

“…Salmonella enterica serovar Typhimurium (S. Typhimurium) is a leading cause of salmonellosis. Poultry and poultry products are implicated in transmission of…”
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A type 6 secretion system (T6SS) encoded gene within Salmonella enterica serovar Enteritidis contributes to virulence by Troxell, Bryan

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Borrelia burgdorferi, a Pathogen That Lacks Iron, Encodes Manganese-dependent Superoxide Dismutase Essential for Resistance to Streptonigrin by Troxell, Bryan, Xu, Haijun, Yang, X. Frank

“…Borrelia burgdorferi, the causative agent of Lyme disease, exists in nature through a complex life cycle involving ticks of the Ixodes genus and mammalian…”
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Application of Size Exclusion Chromatography with Multiangle Light Scattering in the Analytical Development of a Preclinical Stage Gene Therapy Program by Troxell, Bryan, Tsai, I-Wei, Shah, Kinjal, Knuckles, Christopher I, Shelton, Sarah, Lindsey, Kate, Cardenas, Selene M Barbosa, Roberts, Taylor

“…To provide safe recombinant adeno-associated viruses (rAAV) to patients, scalable manufacturing processes are required. However, these processes may introduce…”
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Poultry body temperature contributes to invasion control through reduced expression of Salmonella pathogenicity island 1 genes in Salmonella enterica serovars Typhimurium and Enteritidis by Troxell, Bryan, Petri, Nicholas, Daron, Caitlyn, Pereira, Rafaela, Mendoza, Mary, Hassan, Hosni M, Koci, Matthew D

“…Salmonella enterica serovars Typhimurium (S. Typhimurium) and Enteritidis (S. Enteritidis) are foodborne pathogens, and outbreaks are often associated with…”
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Outer surface protein OspC is an antiphagocytic factor that protects Borrelia burgdorferi from phagocytosis by macrophages by Carrasco, Sebastian E, Troxell, Bryan, Yang, Youyun, Brandt, Stephanie L, Li, Hongxia, Sandusky, George E, Condon, Keith W, Serezani, C Henrique, Yang, X Frank

“…Outer surface protein C (OspC) is one of the major lipoproteins expressed on the surface of Borrelia burgdorferi during tick feeding and the early phase of…”
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Positive and Negative Regulation of Glycerol Utilization by the c-di-GMP Binding Protein PlzA in Borrelia burgdorferi by Zhang, Jun-Jie, Chen, Tong, Yang, Youyun, Du, Jimei, Li, Hongxia, Troxell, Bryan, He, Ming, Carrasco, Sebastian E, Gomelsky, Mark, Yang, X Frank

“…, the causative agent of Lyme disease, encounters two disparate host environments during its enzootic life cycle, ticks and mammalian hosts. has a small genome…”
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