Search Results - "Trovão, Filipa"
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Mapping Molecular Recognition of β1,3-1,4-Glucans by a Surface Glycan-Binding Protein from the Human Gut Symbiont Bacteroides ovatus
Published in Microbiology spectrum (22-12-2021)“…A multigene polysaccharide utilization locus (PUL) encoding enzymes and surface carbohydrate (glycan)-binding proteins (SGBPs) was recently identified in…”
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2
Structural Insights into the Molecular Recognition Mechanism of the Cancer and Pathogenic Epitope, LacdiNAc by Immune‐Related Lectins
Published in Chemistry : a European journal (20-05-2021)“…Interactions of glycan‐specific epitopes to human lectin receptors represent novel immune checkpoints for investigating cancer and infection diseases. By…”
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3
The Crystal Structure of the R280K Mutant of Human p53 Explains the Loss of DNA Binding
Published in International journal of molecular sciences (13-04-2018)“…The p53 tumor suppressor is widely found to be mutated in human cancer. This protein is regarded as a molecular hub regulating different cell responses, namely…”
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4
Noncovalent microarrays from synthetic amino-terminating glycans: Implications in expanding glycan microarray diversity and platform comparison
Published in Glycobiology (Oxford) (09-09-2021)“…Abstract Glycan microarrays have played important roles in detection and specificity assignment of glycan recognition by proteins. However, the size and…”
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5
Molecular Recognition of a Thomsen–Friedenreich Antigen Mimetic Targeting Human Galectin‐3
Published in ChemMedChem (08-10-2018)“…Overexpression of the Thomsen–Friedenreich (TF) antigen in cell membrane proteins occurs in 90 % of adenocarcinomas. Additionally, the binding of the TF…”
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The structure of a Bacteroides thetaiotaomicron carbohydrate-binding module provides new insight into the recognition of complex pectic polysaccharides by the human microbiome
Published in Journal of structural biology. X (01-01-2023)“…[Display omitted] •BT0996-C is a carbohydrate-binding module (CBM) from a modular RG-II-degrading enzyme.•BT0996-C has a high content in positively charged…”
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The crystal structure of the R280K mutant of human p53 explains the loss of DNA binding
Published in Acta crystallographica. Section A, Foundations and advances (22-08-2018)“…Abstract only…”
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Synthetic Affinity Ligands for Human Antibodies and Its Different Approaches
Published 01-01-2016“…Antibodies are important biopharmaceutical proteins that can be applied in a wide range of fields, such as in research, disease diagnostics, therapy and as…”
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Dissertation