Search Results - "Trott, Joshua"

A cyclooxygenase-2/prostaglandin E2 pathway augments activation-induced cytosine deaminase expression within replicating human B cells by Lee, Hyunjoo, Trott, Joshua S, Haque, Shabirul, McCormick, Steven, Chiorazzi, Nicholas, Mongini, Patricia K A

“…Within inflammatory environments, B cells encountering foreign or self-Ag can develop tertiary lymphoid tissue expressing activation-induced cytosine deaminase…”
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A p53 axis regulates B cell receptor-triggered, innate immune system-driven B cell clonal expansion by Lee, Hyunjoo, Haque, Shabirul, Nieto, Jennifer, Trott, Joshua, Inman, John K, McCormick, Steven, Chiorazzi, Nicholas, Mongini, Patricia K A

“…Resting mature human B cells undergo a dynamic process of clonal expansion, followed by clonal contraction, during an in vitro response to surrogate C3d-coated…”
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A cyclooxygenase-2 (COX-2) pathway promotes expression of activation-induced cytosine deaminase (AID) within replicating human B cells (84.7) by Mongini, Patricia, Lee, Hyunjoo, Trott, Joshua, Chiorazzi, Nicholas

“…Within an inflammatory milieu, B cells specific for autoantigens or microorganisms can develop tertiary lymphoid foci exhibiting AID, downstream class…”
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A p53 AXIS REGULATES BCR-TRIGGERED, INNATE IMMUNE SYSTEM-DRIVEN B CELL CLONAL EXPANSION1 by Lee, Hyunjoo, Haque, Shabirul, Nieto, Jennifer, Trott, Joshua, Inman, John K., McCormick, Steven, Chiorazzi, Nicholas, Mongini, Patricia K. A.

“…Resting mature human B cells undergo a dynamic process of clonal expansion, followed by clonal contraction, during an in vitro response to surrogate C3d-coated…”
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PGE2 Upregulates Activation-Induced Cytosine Deaminase (AID) in Human B Lymphoblasts (34.12) by Mongini, Patricia K. A., Chiorazzi, Nicholas, Haque, Shabirul, Trott, Joshua

“…AID is expressed in mature B cells during activation and in some non-lymphoid tissues during inflammation and malignancy. Elevated COX-2 & PGE2 characterize…”
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p53 and COX-2 Inhibitors Control the Replication and Viability of Non-Transformed and CLL B Lymphocytes by Mongini, Patricia, Kaufman, Matthew, Kolitz, Jonathan E., Allen, Steven L., Trott, Joshua, Rai, Kanti, Chiorazzi, Nicholas

“…Innate immune system-driven replication of antigen receptor-triggered, non-transformed human B2 cells depends upon BAFF-mediated survival signals. The latter…”
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Different Expression of FcgammaRIIb in Chronic Lymphocytic Leukemia and Human Normal B Lymphocytes by Moreno, Carol, Damle, Rajendra, Jansa, Sonia, Ferrer, Gerardo, Abrisqueta, Pau, Pons, Aina, Aymerich, Marta, Bonvini, Ezio, Trott, Joshua, Montserrat, Emili, Chiorazzi, Nicholas

“…The Fcgamma receptors (FcγRs) are a family of molecules that modulate immune responses. FcγRIIb is an inhibitory FcγR that bears immunoreceptor tyrosine-based…”
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2.40 Paradoxical Effects of Fc Gamma Receptor IIb Engagement on the Modulation of BCR Signaling in Chronic Lymphocytic Leukemia B Cells by Moreno, Carol, Ferrer, Gerardo, Damle, Rajendra, Hodgson, Kate, Jansà, Sonia, Pons, Aina, Bonvini, Ezio, Trott, Joshua, Rai, Kanti R, Montserrat, Emili, Chiorazzi, Nicholas

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Surface expression of Bcl-2 in chronic lymphocytic leukemia and other B-cell leukemias and lymphomas without a breakpoint t(14;18) by McCarthy, Brian A, Boyle, Erin, Wang, Xue Ping, Guzowski, Dorothy, Paul, Santanu, Catera, Rosa, Trott, Joshua, Yan, Xiao-jie, Croce, Carlo M, Damle, Rajendra, Yancopoulos, Sophia, Messmer, Bradley T, Lesser, Martin, Allen, Steven L, Rai, Kanti R, Chiorazzi, Nicholas

“…Since its discovery in follicular lymphoma cells at the breakpoint t(14;18), Bcl-2 has been studied extensively in many basic and clinical science settings…”
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