Search Results - "Tropè, Claes G"
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Notch3 Overexpression Is Related to the Recurrence of Ovarian Cancer and Confers Resistance to Carboplatin
Published in The American journal of pathology (01-09-2010)“…Amplification of the Notch3 locus has been detected in ovarian high-grade serous carcinoma (HGSC), the most common and malignant type of ovarian cancer. We…”
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Defining a prognostic marker panel for patients with ovarian serous carcinoma effusion
Published in Human pathology (01-11-2013)“…Summary Advanced-stage ovarian carcinoma is a highly lethal malignancy, yet no widely accepted prognostic panels exist to date in this disease. The objective…”
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The clinicopathological and prognostic impact of 14-3-3 sigma expression on vulvar squamous cell carcinomas
Published in BMC cancer (24-10-2008)“…14-3-3 sigma promotes G2/M cell cycle arrest by sequestering cyclin B1-CDC2 complex in cytoplasm. Down-regulation of 14-3-3sigma, which has been demonstrated…”
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Neoadjuvant Chemotherapy or Primary Surgery in Stage IIIC or IV Ovarian Cancer
Published in The New England journal of medicine (02-09-2010)“…In this randomized trial, standard primary debulking surgery followed by chemotherapy was compared with neoadjuvant chemotherapy followed by debulking surgery…”
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The clinical and diagnostic role of microRNAs in ovarian carcinoma
Published in Gynecologic oncology (01-06-2014)“…Abstract Objective MicroRNAs (miRNAs, miRs) are non-coding RNAs which post-transcriptionally regulate mRNA synthesis. Data regarding the expression and…”
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Diagnosis and treatment of sarcoma of the uterus. A review
Published in Acta oncologica (01-07-2012)“…The histopathological classification and staging system for uterine sarcoma (US) were revised in 2003 and 2009, respectively. However, there is currently no…”
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Long-Term Outcomes After Pelvic Radiation for Early-Stage Endometrial Cancer
Published in Journal of clinical oncology (01-11-2013)“…This follow-up of a randomized study was conducted to assess the long-term effects of external beam radiation therapy (EBRT) in the adjuvant treatment of…”
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Advanced Ovarian Cancer: Primary or Interval Debulking? Five Categories of Patients in View of the Results of Randomized Trials and Tumor Biology: Primary Debulking Surgery and Interval Debulking Surgery for Advanced Ovarian Cancer
Published in The oncologist (Dayton, Ohio) (01-06-2016)“…Background. Standard treatment of stage III and IV advanced ovarian cancer (AOC) consists of primary debulking surgery (PDS) followed by chemotherapy. Since…”
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Ovarian cancer: diagnostic, biological and prognostic aspects
Published in Women's Health (01-09-2014)“…Ovarian cancer remains the most lethal gynecologic malignancy, owing to late detection, intrinsic and acquired chemoresistance and remarkable heterogeneity…”
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MicroRNAs in Ovarian Cancer
Published in Human pathology (01-09-2015)“…Summary Ovarian cancer, consisting predominantly of ovarian carcinoma, is the eighth most common cancer in women and the most lethal gynecologic malignancy…”
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Wee1 is a novel independent prognostic marker of poor survival in post-chemotherapy ovarian carcinoma effusions
Published in Gynecologic oncology (01-10-2014)“…Abstract Objective Wee1-like kinase (Wee1) is a tyrosine kinase which negatively regulates entry into mitosis at the G2 to M-phase transition and has a role in…”
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Epithelial-mesenchymal transition in ovarian carcinoma
Published in Frontiers in oncology (2012)“…Ovarian cancer is the most lethal gynecologic malignancy, with the majority of patients dying within 5 years of diagnosis. This poor survival of patients…”
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Ezrin Is Associated with Disease Progression in Ovarian Carcinoma
Published in PloS one (13-09-2016)“…Ezrin and p130Cas are structural proteins with an important role in signaling pathways and have been shown to promote cancer dissemination. We previously…”
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Argonaute, Dicer, and Drosha are up-regulated along tumor progression in serous ovarian carcinoma
Published in Human pathology (01-11-2012)“…Summary MicroRNAs are posttranscriptional regulators of messenger RNA synthesis that are intracellularly processed and transferred by the microRNA-regulating…”
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Expression and clinical role of long non-coding RNA in high-grade serous carcinoma
Published in Gynecologic oncology (01-03-2018)“…To profile long non-coding RNA (lncRNA) expression at the various anatomic sites of high-grades serous carcinoma (HGSC) and in effusion-derived exosomes…”
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TSAP6 is a novel candidate marker of poor survival in metastatic high-grade serous carcinoma
Published in Human pathology (01-02-2017)“…The objective of this study was to analyze the expression and clinical role of molecules involved in exosome synthesis and secretion in high-grade serous…”
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A Risk Model for Secondary Cytoreductive Surgery in Recurrent Ovarian Cancer: An Evidence-Based Proposal for Patient Selection
Published in Annals of surgical oncology (01-02-2012)“…Background To develop a risk model for predicting complete secondary cytoreductive surgery (SCR) in patients with recurrent ovarian cancer. Methods Individual…”
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The microRNA miR-192/215 family is upregulated in mucinous ovarian carcinomas
Published in Scientific reports (23-07-2018)“…Different microRNAs are dysregulated in ovarian cancer where some of them have proved to be valid biomarkers. miRNA profiling analyses have shown that the…”
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Phospholipase D messenger RNA expression and clinical role in high-grade serous carcinoma
Published in Human pathology (01-04-2017)“…The objective of this study was to analyze the expression and clinical role of phospholipase D (PLD) in high-grade serous carcinoma (HGSC). PLD1 and PLD2…”
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Neoadjuvant chemotherapy, interval debulking surgery or primary surgery in ovarian carcinoma FIGO stage IV?
Published in European journal of cancer (1990) (01-09-2012)“…Abstract Objectives The aim of this study was to investigate the impact of surgical approach, the extent of surgery and chemotherapy on overall survival in…”
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