Search Results - "Troost, Esther G. C."
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Radiomics for residual tumour detection and prognosis in newly diagnosed glioblastoma based on postoperative [11C] methionine PET and T1c-w MRI
Published in Scientific reports (25-02-2024)“…Personalized treatment strategies based on non-invasive biomarkers have potential to improve patient management in patients with newly diagnosed glioblastoma…”
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Challenges and caveats of a multi-center retrospective radiomics study: an example of early treatment response assessment for NSCLC patients using FDG-PET/CT radiomics
Published in PloS one (03-06-2019)“…Prognostic models based on individual patient characteristics can improve treatment decisions and outcome in the future. In many (radiomic) studies, small size…”
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Analysis of MRI and CT-based radiomics features for personalized treatment in locally advanced rectal cancer and external validation of published radiomics models
Published in Scientific reports (17-06-2022)“…Radiomics analyses commonly apply imaging features of different complexity for the prediction of the endpoint of interest. However, the prognostic value of…”
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Stereotactic ablative body radiotherapy (SABR) combined with immunotherapy (L19-IL2) versus standard of care in stage IV NSCLC patients, ImmunoSABR: a multicentre, randomised controlled open-label phase II trial
Published in BMC cancer (15-06-2020)“…About 50% of non-small cell lung cancer (NSCLC) patients have metastatic disease at initial diagnosis, which limits their treatment options and, consequently,…”
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Integrated radiogenomics analyses allow for subtype classification and improved outcome prognosis of patients with locally advanced HNSCC
Published in Scientific reports (06-10-2022)“…Patients with locally advanced head and neck squamous cell carcinoma (HNSCC) may benefit from personalised treatment, requiring biomarkers that characterize…”
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Correction: Lung cancer multi-omics digital human avatars for integrating precision medicine into clinical practice: the LANTERN study
Published in BMC cancer (09-11-2023)Get full text
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Comparison of different treatment planning approaches for intensity-modulated proton therapy with simultaneous integrated boost for pancreatic cancer
Published in Radiation oncology (London, England) (22-11-2018)“…Neoadjuvant radio(chemo)therapy of non-metastasized, borderline resectable or unresectable locally advanced pancreatic cancer is complex and prone to cause…”
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Multiparametric imaging of patient and tumour heterogeneity in non-small-cell lung cancer: quantification of tumour hypoxia, metabolism and perfusion
Published in European journal of nuclear medicine and molecular imaging (01-02-2016)“…Purpose Multiple imaging techniques are nowadays available for clinical in-vivo visualization of tumour biology. FDG PET/CT identifies increased tumour…”
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Evaluation of tumour hypoxia during radiotherapy using [18F]HX4 PET imaging and blood biomarkers in patients with head and neck cancer
Published in European journal of nuclear medicine and molecular imaging (01-11-2016)“…Background and purpose Increased tumour hypoxia is associated with a worse overall survival in patients with head and neck squamous cell carcinoma (HNSCC). The…”
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Impact of robust treatment planning on single- and multi-field optimized plans for proton beam therapy of unilateral head and neck target volumes
Published in Radiation oncology (London, England) (28-11-2017)“…Proton beam therapy is promising for the treatment of head and neck cancer (HNC), but it is sensitive to uncertainties in patient positioning and particle…”
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Assessing robustness of radiomic features by image perturbation
Published in Scientific reports (24-01-2019)“…Image features need to be robust against differences in positioning, acquisition and segmentation to ensure reproducibility. Radiomic models that only include…”
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Reduction of intrafraction pancreas motion using an abdominal corset compatible with proton therapy and MRI
Published in Clinical and translational radiation oncology (01-01-2023)“…•PE based abdominal corset allows compression in MRI and PT.•Pancreas motion in patients with abdominal tumours reduced significantly.•Patient comfort during…”
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[18F]FDG PET/CT-based response assessment of stage IV non-small cell lung cancer treated with paclitaxel-carboplatin-bevacizumab with or without nitroglycerin patches
Published in European journal of nuclear medicine and molecular imaging (01-01-2017)“…Purpose Nitroglycerin (NTG) is a vasodilating drug, which increases tumor blood flow and consequently decreases hypoxia. Therefore, changes in [18F]…”
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Semiautomatic methods for segmentation of the proliferative tumour volume on sequential FLT PET/CT images in head and neck carcinomas and their relation to clinical outcome
Published in European journal of nuclear medicine and molecular imaging (01-05-2014)“…Purpose Radiotherapy of head and neck cancer induces changes in tumour cell proliferation during treatment, which can be depicted by the PET tracer 18…”
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Increased relative biological effectiveness and periventricular radiosensitivity in proton therapy of glioma patients
Published in Radiotherapy and oncology (01-01-2023)“…•Regional intra-cerebral variation in tissue response after proton therapy.•Increased relative biological effectiveness of proton therapy.•Spatial accumulation…”
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18F-fluorodeoxyglucose positron-emission tomography (FDG-PET)-Radiomics of metastatic lymph nodes and primary tumor in non-small cell lung cancer (NSCLC) - A prospective externally validated study
Published in PloS one (01-03-2018)“…Lymph node stage prior to treatment is strongly related to disease progression and poor prognosis in non-small cell lung cancer (NSCLC). However, few studies…”
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Correlation of [18F]FMISO autoradiography and pimonodazole immunohistochemistry in human head and neck carcinoma xenografts
Published in European Journal of Nuclear Medicine (01-10-2008)“…Purpose Tumour cell hypoxia is a common feature in solid tumours adversely affecting radiosensitivity and chemosensitivity in head and neck squamous cell…”
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PET in the management of locally advanced and metastatic NSCLC
Published in Nature reviews. Clinical oncology (01-07-2015)“…Key Points Disease-specific survival of patients with advanced-stage non-small-cell lung cancer remains poor; combined and intensified treatments have failed…”
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Investigation of inter‐fraction target motion variations in the context of pencil beam scanned proton therapy in non‐small cell lung cancer patients
Published in Medical physics (Lancaster) (01-09-2020)“…Purpose For locally advanced‐stage non‐small cell lung cancer (NSCLC), inter‐fraction target motion variations during the whole time span of a fractionated…”
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Longitudinal and Multimodal Radiomics Models for Head and Neck Cancer Outcome Prediction
Published in Cancers (21-01-2023)“…Radiomics analysis provides a promising avenue towards the enabling of personalized radiotherapy. Most frequently, prognostic radiomics models are based on…”
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