Search Results - "Troncoso, J.C"

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    Midlife adiposity predicts earlier onset of Alzheimer’s dementia, neuropathology and presymptomatic cerebral amyloid accumulation by Chuang, Y-F, An, Y, Bilgel, M, Wong, D F, Troncoso, J C, O'Brien, R J, Breitner, J C, Ferrucci, L, Resnick, S M, Thambisetty, M

    Published in Molecular psychiatry (01-07-2016)
    “…Understanding how midlife risk factors influence age at onset (AAO) of Alzheimer’s disease (AD) may provide clues to delay disease expression. Although midlife…”
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    Alpha-2 macroglobulin in Alzheimer’s disease: a marker of neuronal injury through the RCAN1 pathway by Varma, V R, Varma, S, An, Y, Hohman, T J, Seddighi, S, Casanova, R, Beri, A, Dammer, E B, Seyfried, N T, Pletnikova, O, Moghekar, A, Wilson, M R, Lah, J J, O'Brien, R J, Levey, A I, Troncoso, J C, Albert, M S, Thambisetty, M

    Published in Molecular psychiatry (01-01-2017)
    “…Preclinical changes that precede the onset of symptoms and eventual diagnosis of Alzheimer’s disease (AD) are a target for potential preventive interventions…”
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    Recurrent cerebral venous thrombosis associated with heterozygote methylenetetrahydrofolate reductase C677 T mutation and sickle cell trait without homocysteinemia: An autopsy case report and review of literature by Ali, Z, Troncoso, J.C, Fowler, D.R

    Published in Forensic science international (2014)
    “…Highlights • MTHFR mutation increases the risk for thrombosis, if associated with minor or major risk factors for thrombophilia. • To date, 40 mutations of…”
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    Recurrent cerebral venous thrombosis associated with heterozygote methylenetetrahydrofolate reductase C677T mutation and sickle cell trait without homocysteinemia: An autopsy case report and review of literature by Ali, Z., Troncoso, J.C., Fowler, D.R.

    Published in Forensic science international (01-09-2014)
    “…•MTHFR mutation increases the risk for thrombosis, if associated with minor or major risk factors for thrombophilia.•To date, 40 mutations of MTHFR gene have…”
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    Journal Article
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    Effect of aluminum and other multivalent cations on neurofilaments in vitro: an electron microscopic study by Troncoso, J C, March, J L, Häner, M, Aebi, U

    Published in Journal of structural biology (01-03-1990)
    “…Using electron microscopy (EM) of negatively stained samples, we have systematically explored the effect of aluminum and other multivalent cations on…”
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    Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease by West, M J, Coleman, P D, Flood, D G, Troncoso, J C

    Published in The Lancet (British edition) (17-09-1994)
    “…The distinction between the neurodegenerative changes that accompany normal ageing and those that characterise Alzheimer's disease is not clear. The resolution…”
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    Glutamate excitotoxicity: A mechanism of neurologic injury associated with hypothermic circulatory arrest by Redmond, J.M., Gillinov, A.M., Zehr, K.J., Blue, M.E., Troncoso, J.C., Reitz, B.A., Cameron, D.E., Johnston, M.V., Baumgartner, W.A.

    “…Glutamate, the major central nervous system neurotransmitter, may have potent neurotoxic activity under conditions of metabolic stress. By receptor…”
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    Clinical features of inherited cerebellar degeneration in Gordon setters by Steinberg, H S, Troncoso, J C, Cork, L C, Price, D L

    “…We evaluated a kindred of Gordon Setters affected with inherited ataxia. Six adults and 4 pups clinically affected by the disease were examined. Pathologic…”
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