Search Results - "Tronchere, H"
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IL-26 in the induced sputum is associated with the level of systemic inflammation, lung functions and body weight in COPD patients
Published in International journal of chronic obstructive pulmonary disease (01-01-2018)“…Chronic inflammatory process is the main link in COPD pathogenesis, which causes structural changes in the respiratory tract and lungs. In overweight patients,…”
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C.P.10 Phosphatase inactive myotubularin rescues X-linked centronuclear (myotubular) myopathy phenotypes in mice
Published in Neuromuscular disorders : NMD (01-10-2012)“…Abstract The X-linked centronuclear myopathy, also called myotubular myopathy, is a muscle disorder characterized by neonatal hypotonia and abnormal organelles…”
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Phosphorylation Regulates in vivo Interaction and Molecular Targeting of Serine/Arginine-Rich Pre-mRNA Splicing Factors
Published in The Journal of cell biology (03-05-1999)“…The SR superfamily of splicing factors and regulators is characterized by arginine/serine (RS)-rich domains, which are extensively modified by phosphorylation…”
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Implication of phosphoinositide phosphatases in genetic diseases: the case of myotubularin
Published in Cellular and molecular life sciences : CMLS (01-10-2003)“…Phosphoinositides play a central role in the control of major eukaryotic cell signaling mechanisms. Accordingly, the list of phosphoinositide-metabolizing…”
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Elevated levels of PtdIns5P in NPM-ALK transformed cells: Implication of PIKfyve
Published in Biochemical and biophysical research communications (25-07-2008)“…Phosphatidylinositol 5-monophosphate (PtdIns5P), one of the latest phosphoinositides discovered, has been suggested to play important cellular functions. Here,…”
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118th ENMC International Workshop on Advances in Myotubular Myopathy. 26–28 September 2003, Naarden, The Netherlands. (5th Workshop of the International Consortium on Myotubular Myopathy)
Published in Neuromuscular disorders : NMD (01-06-2004)Get full text
Journal Article Conference Proceeding -
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RGS12 and RGS14 GoLoco motifs are G alpha(i) interaction sites with guanine nucleotide dissociation inhibitor Activity
Published in The Journal of biological chemistry (03-08-2001)“…The regulators of G-protein signaling (RGS) proteins accelerate the intrinsic guanosine triphosphatase activity of heterotrimeric G-protein alpha subunits and…”
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Inhibition of Rac controls NPM-ALK-dependent lymphoma development and dissemination
Published in Blood cancer journal (New York) (01-06-2011)“…Nucleophosmin-anaplastic lymphoma kinase (NPM–ALK) is a tyrosine kinase oncogene responsible for the pathogenesis of the majority of human ALK-positive…”
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Phorbol myristate acetate stimulates [3H]choline incorporation into phosphatidylcholine independently of the de novo pathway in Krebs-II ascitic cells : a unique effect of phorbol ester on choline uptake
Published in Biochemical journal (01-08-1993)“…The effect of phorbol 12-myristate 13-acetate (PMA) on [3H]choline incorporation into phosphatidylcholine (PtdCho) and on the 'de novo' pathway of PtdCho…”
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Reversible translocation of cytidylyltransferase between cytosol and endoplasmic reticulum occurs within minutes in whole cells
Published in Biochemical journal (01-03-1992)“…Addition of oleic acid to Krebs II cells induced a rapid incorporation of [3H]choline into phosphatidylcholine, since 500 microM of the fatty acid stimulated…”
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PtdIns(5)P activates the host cell PI3-kinase/Akt pathway during Shigella flexneri infection
Published in The EMBO journal (08-03-2006)“…The virulence factor IpgD, delivered into nonphagocytic cells by the type III secretion system of the pathogen Shigella flexneri, is a phosphoinositide…”
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Phosphoinositide signaling disorders in human diseases
Published in FEBS Letters (03-07-2003)“…Phosphoinositides (PIs) play an essential role in diverse cellular functions. Their intracellular level is strictly regulated by specific PI kinases,…”
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Book Review Journal Article -
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Purification and Characterization of a Kinase Specific for the Serine-and Arginine-Rich Pre-mRNA Splicing Factors
Published in Proceedings of the National Academy of Sciences - PNAS (08-11-1994)“…Members of the SR family of pre-mRNA splicing factors are phosphoproteins that share a phosphoepitope specifically recognized by monoclonal antibody (mAb) 104…”
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Expression of myotubularins in blood platelets: Characterization and potential diagnostic of X-linked myotubular myopathy
Published in Biochemical and biophysical research communications (29-07-2016)“…Phosphoinositides play a key role in the spatiotemporal control of central intracellular processes and several specific kinases and phosphatases regulating the…”
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Cholecystokinin and gastrin peptides stimulate ODC activity in a rat pancreatic cell line
Published in The American journal of physiology (01-05-1989)“…Recent studies have demonstrated that cholecystokinin (CCK) receptors are heterologous in peripheral tissues and in the central nervous system and that…”
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Production of Phosphatidylinositol 5-Phosphate by the Phosphoinositide 3-Phosphatase Myotubularin in Mammalian Cells
Published in The Journal of biological chemistry (20-02-2004)“…MTM1, the gene encoding myotubularin (MTM1), is mutated in the X-linked myotubular myopathy (XLMTM), a severe genetic muscular disorder. MTM1 is a…”
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Lipid rafts are critical membrane domains in blood platelet activation processes
Published in BBA - Biomembranes (10-03-2003)“…Among the various hematopoı̈etic cells, platelets are critical for maintaining the integrity of the vascular system. They must be rapidly activated by…”
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Book Review Journal Article -
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Integrin-dependent interaction of lipid rafts with the actin cytoskeleton in activated human platelets
Published in Journal of cell science (15-02-2005)“…Dynamic connections between actin filaments and the plasma membrane are crucial for the regulation of blood platelet functions. Protein complexes associated…”
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