Search Results - "Tronche, François"

Chronic Stress Triggers Social Aversion via Glucocorticoid Receptor in Dopaminoceptive Neurons by Barik, Jacques, Marti, Fabio, Morel, Carole, Fernandez, Sebastian P., Lanteri, Christophe, Godeheu, Gérard, Tassin, Jean-Pol, Mombereau, Cédric, Faure, Philippe, Tronche, François

“…Repeated traumatic events induce long-lasting behavioral changes that are key to organism adaptation and that affect cognitive, emotional, and social…”
Get full text

SWI/SNF chromatin remodeler complex within the reward pathway is required for behavioral adaptations to stress by Zayed, Abdallah, Baranowski, Camille, Compagnion, Anne-Claire, Vernochet, Cécile, Karaki, Samah, Cuttoli, Romain Durand-de, Saint-Jour, Estefani, Bhattacharya, Soumee, Marti, Fabio, Vanhoutte, Peter, Yaniv, Moshe, Faure, Philippe, Barik, Jacques, Amar, Laurence, Tronche, François, Parnaudeau, Sébastien

“…Enduring behavioral changes upon stress exposure involve changes in gene expression sustained by epigenetic modifications in brain circuits, including the…”
Get full text

Intrahepatic Bile Ducts Develop According to a New Mode of Tubulogenesis Regulated by the Transcription Factor SOX9 by Antoniou, Aline, Raynaud, Peggy, Cordi, Sabine, Zong, Yiwei, Tronche, François, Stanger, Ben Z, Jacquemin, Patrick, Pierreux, Christophe E, Clotman, Frederic, Lemaigre, Frederic P

“…Background & Aims A number of diseases are characterized by defective formation of the intrahepatic bile ducts. In the embryo, hepatoblasts differentiate to…”
Get full text

TLR9 activation via microglial glucocorticoid receptors contributes to degeneration of midbrain dopamine neurons by Maatouk, Layal, Compagnion, Anne-Claire, Sauvage, Maria-Angeles Carrillo-de, Bemelmans, Alexis-Pierre, Leclere-Turbant, Sabrina, Cirotteau, Vincent, Tohme, Mira, Beke, Allen, Trichet, Michaël, Bazin, Virginie, Trawick, Bobby N., Ransohoff, Richard M., Tronche, François, Manoury, Bénédicte, Vyas, Sheela

“…Inflammation is a characteristic feature of Parkinson’s disease (PD). We examined the role of TLR9 and its regulation by glucocorticoid receptors (GRs) in…”
Get full text

The neural androgen receptor: a therapeutic target for myelin repair in chronic demyelination by HUSSAIN, Rashad, GHOUMARI, Abdel M, TRONCHE, François, SITRUK-WARE, Regine, SCHUMACHER, Michael, SAID GHANDOUR, M, BIELECKI, Bartosz, STEIBEL, Jérôme, BOEHM, Nelly, LIERE, Philippe, MACKLIN, Wendy B, KUMAR, Narender, HABERT, René, MHAOUTY-KODJA, Sakina

“…Myelin regeneration is a major therapeutic goal in demyelinating diseases, and the failure to remyelinate rapidly has profound consequences for the health of…”
Get full text

Conditional Inactivation of Androgen Receptor Gene in the Nervous System: Effects on Male Behavioral and Neuroendocrine Responses by Raskin, Kalina, de Gendt, Karel, Duittoz, Anne, Liere, Philippe, Verhoeven, Guido, Tronche, Francois, Mhaouty-Kodja, Sakina

“…Testosterone (T) profoundly influences central sexual differentiation and functions. In the brain, T signals either directly through androgen receptor (AR) or…”
Get full text

Glucocorticoid receptor in astrocytes regulates midbrain dopamine neurodegeneration through connexin hemichannel activity by Maatouk, Layal, Yi, Chenju, Carrillo-de Sauvage, Maria-Angeles, Compagnion, Anne-Claire, Hunot, Stéphane, Ezan, Pascal, Hirsch, Etienne C., Koulakoff, Annette, Pfrieger, Frank W, Tronche, François, Leybaert, Luc, Giaume, Christian, Vyas, Sheela

“…The precise contribution of astrocytes in neuroinflammatory process occurring in Parkinson’s disease (PD) is not well characterized. In this study, using GR…”
Get full text

Microglial glucocorticoid receptors play a pivotal role in regulating dopaminergic neurodegeneration in parkinsonism by Ros-Bernal, Francisco, Hunot, Stéphane, Herrero, Maria Trinidad, Parnadeau, Sebastien, Corvol, Jean-Christophe, Lu, Lixia, Alvarez-Fischer, Daniel, Carrillo-de Sauvage, María Angeles, Saurini, Françoise, Coussieu, Christiane, Kinugawa, Kiyoka, Prigent, Annick, Höglinger, Günter, Hamon, Michel, Tronche, François, Hirsch, Etienne C, Vyas, Sheela

“…Among the pathogenic processes contributing to dopaminergic neuron (DN) death in Parkinson disease (PD), evidence points to non-cell-autonomous mechanisms,…”
Get full text

Dopamine Neuron Activity and Stress Signaling as Links Between Social Hierarchy and Psychopathology Vulnerability by Battivelli, Dorian, Vernochet, Cécile, Conabady, Estelle, Nguyen, Claire, Zayed, Abdallah, Lebel, Ashley, Meirsman, Aura Carole, Messaoudene, Sarah, Fieggen, Alexandre, Dreux, Gautier, Rigoni, Daiana, Le Borgne, Tinaïg, Marti, Fabio, Contesse, Thomas, Barik, Jacques, Tassin, Jean-Pol, Faure, Philippe, Parnaudeau, Sébastien, Tronche, François

“…Social status in humans, generally reflected by socioeconomic status, has been associated, when constrained, with heightened vulnerability to pathologies…”
Get full text

Resetting of Circadian Time in Peripheral Tissues by Glucocorticoid Signaling by Balsalobre, Aurélio, Brown, Steven A., Marcacci, Lysiane, Tronche, FranÇois, Kellendonk, Christoph, Reichardt, Holger M., Schütz, Günther, Schibler, Ueli

“…In mammals, circadian oscillators reside not only in the suprachiasmatic nucleus of the brain, which harbors the central pacemaker, but also in most peripheral…”
Get full text

The glucocorticoid receptor in the nucleus accumbens plays a crucial role in social rank attainment in rodents by Papilloud, Aurélie, Weger, Meltem, Bacq, Alexandre, Zalachoras, Ioannis, Hollis, Fiona, Larrieu, Thomas, Battivelli, Dorian, Grosse, Jocelyn, Zanoletti, Olivia, Parnaudeau, Sébastien, Tronche, François, Sandi, Carmen

“…•High anxious, submissive-prone rats show lower GR expression in the NAc.•Viral downregulation of GR in the NAc in rats leads to improved social rank.•Mice…”
Get full text

Presynaptic D2 Dopamine Receptors Control Long-Term Depression Expression and Memory Processes in the Temporal Hippocampus by Rocchetti, Jill, Isingrini, Elsa, Dal Bo, Gregory, Sagheby, Sara, Menegaux, Aurore, Tronche, François, Levesque, Daniel, Moquin, Luc, Gratton, Alain, Wong, Tak Pan, Rubinstein, Marcelo, Giros, Bruno

“…Abstract Background Dysfunctional mesocorticolimbic dopamine signaling has been linked to alterations in motor and reward-based functions associated with…”
Get full text

Dlx5 and Dlx6 expression in GABAergic neurons controls behavior, metabolism, healthy aging and lifespan by de Lombares, Camille, Heude, Eglantine, Alfama, Gladys, Fontaine, Anastasia, Hassouna, Rim, Vernochet, Cécile, de Chaumont, Fabrice, Olivo-Marin, Christophe, Ey, Elodie, Parnaudeau, Sébastien, Tronche, François, Bourgeron, Thomas, Luquet, Serge, Levi, Giovanni, Narboux-Nême, Nicolas

“…and encode two homeobox transcription factors expressed by developing and mature GABAergic interneurons. During development, play a role in the differentiation…”
Get full text

Stress and addiction: glucocorticoid receptor in dopaminoceptive neurons facilitates cocaine seeking by Piazza, Pier Vincenzo, Tronche, François, Ambroggi, Frédéric, Turiault, Marc, Milet, Aude, Deroche-Gamonet, Véronique, Parnaudeau, Sébastien, Balado, Eric, Barik, Jacques, van der Veen, Rixt, Maroteaux, Grégoire, Lemberger, Thomas, Schütz, Günther, Lazar, Monique, Marinelli, Michela

“…The glucocorticoid receptor is a ubiquitous transcription factor mediating adaptation to environmental challenges and stress. Selective Nr3c1 (the…”
Get full text

Deleting IGF-1 receptor from forebrain neurons confers neuroprotection during stroke and upregulates endocrine somatotropin by De Magalhaes Filho, C Daniel, Kappeler, Laurent, Dupont, Joëlle, Solinc, Julien, Villapol, Sonia, Denis, Cécile, Nosten-Bertrand, Marika, Billard, Jean-Marie, Blaise, Annick, Tronche, François, Giros, Bruno, Charriaut-Marlangue, Christiane, Aïd, Saba, Le Bouc, Yves, Holzenberger, Martin

“…Insulin-like growth factors control numerous processes, namely somatic growth, metabolism and stress resistance, connecting this pathway to aging and…”
Get full text

Conditional deletion of Ndufs4 in dopaminergic neurons promotes Parkinson’s disease-like non-motor symptoms without loss of dopamine neurons by Choi, Won-Seok, Kim, Hyung-Wook, Tronche, François, Palmiter, Richard D., Storm, Daniel R., Xia, Zhengui

“…Reduction of mitochondrial complex I activity is one of the major hypotheses for dopaminergic neuron death in Parkinson’s disease. However, reduction of…”
Get full text

Identification of an acute functional cross-talk between amyloid-β and glucocorticoid receptors at hippocampal excitatory synapses by Kootar, Scherazad, Frandemiche, Marie-Lise, Dhib, Gihen, Mouska, Xavier, Lorivel, Thomas, Poupon-Silvestre, Gwenola, Hunt, Hazel, Tronche, François, Bethus, Ingrid, Barik, Jacques, Marie, Hélène

“…Amyloid-β is a peptide released by synapses in physiological conditions and its pathological accumulation in brain structures necessary for memory processing…”
Get full text

Liver Adenosine Monophosphate-Activated Kinase-α2 Catalytic Subunit Is a Key Target for the Control of Hepatic Glucose Production by Adiponectin and Leptin But Not Insulin by Andreelli, Fabrizio, Foretz, Marc, Knauf, Claude, Cani, Patrice D, Perrin, Christophe, Iglesias, Miguel A, Pillot, Bruno, Bado, André, Tronche, François, Mithieux, Gilles, Vaulont, Sophie, Burcelin, Rémy, Viollet, Benoit

“…The AMP-activated kinase (AMPK) is a serine threonine kinase that functions as a fuel sensor to regulate energy balance at both cellular and whole-body levels…”
Get full text

Macrophages and neutrophils are the targets for immune suppression by glucocorticoids in contact allergy by Tuckermann, Jan P, Kleiman, Anna, Moriggl, Richard, Spanbroek, Rainer, Neumann, Anita, Illing, Anett, Clausen, Björn E, Stride, Brenda, Förster, Irmgard, Habenicht, Andreas J R, Reichardt, Holger M, Tronche, François, Schmid, Wolfgang, Schütz, Günther

“…Glucocorticoids (GCs) are widely used in the treatment of allergic skin conditions despite having numerous side effects. Here we use Cre/loxP-engineered…”
Get full text

Dissecting the Role of Glucocorticoids on Pancreas Development by GESINA, Emilie, TRONCHE, Francois, HERRERA, Pedro, DUCHENE, Belinda, TALES, Willemène, CZERNICHOW, Paul, BREANT, Bernadette

“…Dissecting the Role of Glucocorticoids on Pancreas Development Emilie Gesina 1 , François Tronche 2 , Pedro Herrera 3 , Belinda Duchene 1 , Willemène Tales 1 ,…”
Get full text