Search Results - "Trombetta, A"

Cerebrospinal fluid and plasma biomarkers in individuals at risk for genetic prion disease by Vallabh, Sonia M, Minikel, Eric Vallabh, Williams, Victoria J, Carlyle, Becky C, McManus, Alison J, Wennick, Chase D, Bolling, Anna, Trombetta, Bianca A, Urick, David, Nobuhara, Chloe K, Gerber, Jessica, Duddy, Holly, Lachmann, Ingolf, Stehmann, Christiane, Collins, Steven J, Blennow, Kaj, Zetterberg, Henrik, Arnold, Steven E

“…Prion disease is neurodegenerative disease that is typically fatal within months of first symptoms. Clinical trials in this rapidly declining symptomatic…”
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A Multidimensional Critical State Analysis for Detecting Intrusions in SCADA Systems by Carcano, A, Coletta, A, Guglielmi, M, Masera, M, Fovino, I Nai, Trombetta, A

“…A relatively new trend in Critical Infrastructures (e.g., power plants, nuclear plants, energy grids, etc.) is the massive migration from the classic model of…”
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Increased levels of the synaptic proteins PSD-95, SNAP-25, and neurogranin in the cerebrospinal fluid of patients with Alzheimer's disease by Kivisäkk, Pia, Carlyle, Becky C, Sweeney, Thadryan, Quinn, James P, Ramirez, Christopher E, Trombetta, Bianca A, Mendes, Muriel, Brock, Mary, Rubel, Carrie, Czerkowicz, Julie, Graham, Danielle, Arnold, Steven E

“…There is currently a lack of reliable and easily accessible biomarkers predicting cognitive decline in Alzheimer's disease (AD). Synaptic dysfunction and loss…”
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Author Correction: Location and function of TDP-43 in platelets, alterations in neurodegenerative diseases and arising considerations for current plasma biobank protocols by Luthi-Carter, Ruth, Cappelli, Sara, Le Roux-Bourdieu, Morgan, Tentillier, Noemie, Quinn, James P., Petrozziello, Tiziana, Gopalakrishnan, Lathika, Sethi, Purva, Choudhary, Himanshi, Bartolini, Giorgia, Gebara, Elias, Stuani, Cristiana, Font, Laure, An, Jiyan, Ortega, Vanessa, Sage, Jessica, Kosa, Edina, Trombetta, Bianca A., Simeone, Roberto, Seredenina, Tamara, Afroz, Tariq, Berry, James D., Arnold, Steven E., Carlyle, Becky C., Adolfsson, Oskar, Sadri-Vakili, Ghazaleh, Buratti, Emanuele, Bowser, Robert, Agbas, Abdulbaki

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Correlations between blood perfusion and dermal thickness in different skin areas of systemic sclerosis patients by Ruaro, B., Sulli, A., Pizzorni, C., Paolino, S., Smith, V., Alessandri, E., Trombetta, A.C., Alsheyyab, J., Cutolo, M.

“…To identify possible correlations between skin blood perfusion (BP) and dermal thickness (DT) in different skin areas of systemic sclerosis (SSc) patients…”
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Location and function of TDP-43 in platelets, alterations in neurodegenerative diseases and arising considerations for current plasma biobank protocols by Luthi-Carter, Ruth, Cappelli, Sara, Le Roux-Bourdieu, Morgan, Tentillier, Noemie, Quinn, James P., Petrozziello, Tiziana, Gopalakrishnan, Lathika, Sethi, Purva, Choudhary, Himanshi, Bartolini, Giorgia, Gebara, Elias, Stuani, Cristiana, Font, Laure, An, Jiyan, Ortega, Vanessa, Sage, Jessica, Kosa, Edina, Trombetta, Bianca A., Simeone, Roberto, Seredenina, Tamara, Afroz, Tariq, Berry, James D., Arnold, Steven E., Carlyle, Becky C., Adolfsson, Oskar, Sadri-Vakili, Ghazaleh, Buratti, Emanuele, Bowser, Robert, Agbas, Abdulbaki

“…The TAR DNA Binding Protein 43 (TDP-43) has been implicated in the pathogenesis of human neurodegenerative diseases and exhibits hallmark neuropathology in…”
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The technical reliability and biotemporal stability of cerebrospinal fluid biomarkers for profiling multiple pathophysiologies in Alzheimer's disease by Trombetta, Bianca A, Carlyle, Becky C, Koenig, Aaron M, Shaw, Leslie M, Trojanowski, John Q, Wolk, David A, Locascio, Joseph J, Arnold, Steven E

“…Alzheimer's disease (AD) is a complex neurodegenerative disease driven by multiple interacting pathophysiological processes that ultimately results in synaptic…”
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Plasma biomarkers for diagnosis of Alzheimer's disease and prediction of cognitive decline in individuals with mild cognitive impairment by Kivisäkk, Pia, Carlyle, Becky C, Sweeney, Thadryan, Trombetta, Bianca A, LaCasse, Kathryn, El-Mufti, Leena, Tuncali, Idil, Chibnik, Lori B, Das, Sudeshna, Scherzer, Clemens R, Johnson, Keith A, Dickerson, Bradford C, Gomez-Isla, Teresa, Blacker, Deborah, Oakley, Derek H, Frosch, Matthew P, Hyman, Bradley T, Aghvanyan, Anahit, Bathala, Pradeepthi, Campbell, Christopher, Sigal, George, Stengelin, Martin, Arnold, Steven E

“…The last few years have seen major advances in blood biomarkers for Alzheimer's Disease (AD) with the development of ultrasensitive immunoassays, promising to…”
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MIR221/MIR222-driven post-transcriptional regulation of P27KIP1 and P57KIP2 is crucial for high-glucose-and AGE-mediated vascular cell damage by TOGLIATTO, G, TROMBETTA, A, DENTELLI, P, ROSSO, A, BRIZZI, M. F

“…MicroRNAs (miRNAs) are a novel group of small non-coding RNAs that regulate gene expression at the post-transcriptional level and act on their target mRNAs in…”
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Proteomic Approaches for the Discovery of Biofluid Biomarkers of Neurodegenerative Dementias by Carlyle, Becky C, Trombetta, Bianca A, Arnold, Steven E

“…Neurodegenerative dementias are highly complex disorders driven by vicious cycles of intersecting pathophysiologies. While most can be definitively diagnosed…”
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CYP46A1 activation by low-dose efavirenz enhances brain cholesterol metabolism in subjects with early Alzheimer's disease by Lerner, Alan J, Arnold, Steven E, Maxfield, Erin, Koenig, Aaron, Toth, Maria E, Fortin, Brooke, Mast, Natalia, Trombetta, Bianca A, Denker, John, Pieper, Andrew A, Tatsuoka, Curtis, Raghupathy, Sangeetha, Pikuleva, Irina A

“…Efavirenz is an anti-HIV drug, and cytochrome P450 46A1 (CYP46A1) is a CNS-specific enzyme that metabolizes cholesterol to 24-hydroxycholesterol (24HC). We…”
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Plasma and cerebrospinal fluid inflammation and the blood-brain barrier in older surgical patients: the Role of Inflammation after Surgery for Elders (RISE) study by Vasunilashorn, Sarinnapha M, Ngo, Long H, Dillon, Simon T, Fong, Tamara G, Carlyle, Becky C, Kivisäkk, Pia, Trombetta, Bianca A, Vlassakov, Kamen V, Kunze, Lisa J, Arnold, Steven E, Xie, Zhongcong, Inouye, Sharon K, Libermann, Towia A, Marcantonio, Edward R

“…Our understanding of the relationship between plasma and cerebrospinal fluid (CSF) remains limited, which poses an obstacle to the identification of…”
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Retraction Note to: MIR221/MIR222-driven post-transcriptional regulation of P27KIP1 and P57KIP2 is crucial for high-glucose- and AGE-mediated vascular cell damage by Togliatto, G., Trombetta, A., Dentelli, P., Rosso, A., Brizzi, M. F.

“…The authors are retracting this article [1]. Following publication, concerns were raised with respect to some of the western blots and the authors were asked…”
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Long-term follow-up of nailfold videocapillaroscopic changes in dermatomyositis versus systemic sclerosis patients by Pizzorni, C., Cutolo, M., Sulli, A., Ruaro, B., Trombetta, A. C., Ferrari, G., Pesce, G., Smith, V., Paolino, S.

“…To identify nailfold videocapillaroscopy (NVC) changes in patients with dermatomyositis (DM) during a 3-year follow-up and to compare the NVC findings between…”
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IGF2R circular RNA hsa_circ_0131235 expression in the middle temporal cortex is associated with AD pathology by Bigarré, Inès M., Trombetta, Bianca A., Guo, Yan‐jun, Arnold, Steven E., Carlyle, Becky C.

“…Objective To identify circular RNAs as candidates for differential expression in the middle temporal (MT) cortex in a well‐characterized cohort with…”
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Technical Performance Evaluation of Olink Proximity Extension Assay for Blood-Based Biomarker Discovery in Longitudinal Studies of Alzheimer's Disease by Carlyle, Becky C., Kitchen, Robert R., Mattingly, Zoe, Celia, Amanda M., Trombetta, Bianca A., Das, Sudeshna, Hyman, Bradley T., Kivisäkk, Pia, Arnold, Steven E.

“…The core Alzheimer's disease (AD) cerebrospinal fluid (CSF) biomarkers; amyloid-β (Aß), total tau (t-tau), and phosphorylated tau (p-tau181), are strong…”
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Cerebrospinal fluid biomarker profiling of diverse pathophysiological domains in Alzheimer's disease by Trombetta, Bianca A., Wu, Chao‐Yi, Kuo, Evan, Geus, Matthijs B., Dodge, Hiroko H., Carlyle, Becky C., Kivisäkk, Pia, Arnold, Steven E.

“…INTRODUCTION While Alzheimer's disease (AD) is defined by amyloid‐β plaques and tau tangles in the brain, it is evident that many other pathophysiological…”
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A diabetic milieu promotes OCT4 and NANOG production in human visceral-derived adipose stem cells by Dentelli, P., Barale, C., Togliatto, G., Trombetta, A., Olgasi, C., Gili, M., Riganti, C., Toppino, M., Brizzi, M. F.

“…Aims/hypothesis Successful outcomes have been obtained by exploiting adipose-derived stem cells (ASCs) in regenerative medicine. NADPH oxidase (NOX)-generated…”
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Biological effects of sodium phenylbutyrate and taurursodiol in Alzheimer's disease by Arnold, Steven E., Hendrix, Suzanne, Nicodemus‐Johnson, Jessie, Knowlton, Newman, Williams, Victoria J., Burns, Jeffrey M., Crane, Monica, McManus, Alison J., Vaishnavi, Sanjeev N., Arvanitakis, Zoe, Neugroschl, Judith, Bell, Karen, Trombetta, Bianca A., Carlyle, Becky C., Kivisäkk, Pia, Dodge, Hiroko H., Tanzi, Rudolph E., Yeramian, Patrick D., Leslie, Kent

“…INTRODUCTION Sodium phenylbutyrate and taurursodiol (PB and TURSO) is hypothesized to mitigate endoplasmic reticulum stress and mitochondrial dysfunction, two…”
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Pulmonary arterial hypertension in interferonophaties: a case report and a review of the literature by Trombetta, A., Ghirardo, S., Pastore, S., Tesser, A., Piscianz, E., Tommasini, A., Bobbo, M., Taddio, A.

“…Background Pulmonary arterial hypertension consists in an increase of mean pulmonary arterial pressure (PAPm ≥ 25 mmHg), and may lead to right ventricular…”
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