Search Results - "Trofimov, SS"
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Synthesis and antiamnesic activity of a series of N-acylprolyl-containing dipeptides
Published in European journal of medicinal chemistry (1996)“…Esters and amides of a series of N-acylprolyl-containing dipeptides were synthesized. It was established that these substances possess the ability to prevent…”
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Early postnatal effects of noopept and piracetam on declarative and procedural memory of adult male and female rats
Published in Bulletin of experimental biology and medicine (01-06-2005)“…We studied the effect of a new nootropic dipeptide Noopept and reference nootropic preparation piracetam injected subcutaneously on days 8-20 of life on…”
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Designing nootropic dipeptides using an evolutionary-genetic approach
Published in Pharmaceutical chemistry journal (01-01-2006)“…A novel approach to the search for the new groups of biologically active peptides is developed, which is based on the selection of point mutants with respect…”
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Nootropic compound l-pyroglutamyl- d-alanine-amide restores hippocampal long-term potentiation impaired by exposure to ethanol in rats
Published in Neuroscience letters (31-03-1995)“…The characteristics of long-term potentiation (LTP) in the hippocampus of rats prenatally exposed to ethanol and treated postnatally with nootropic compounds…”
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The novel substituted acylproline-containing dipeptide, GVS-111, promotes the restoration of learning and memory impaired by bilateral frontal lobectomy in rats
Published in Behavioural pharmacology (01-06-1997)“…The present study investigated the potential benefit of the ethyl ester of N-phenylacetylprolylglycine (GVS-111) on the model of bilateral frontal lobectomy…”
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New endogenous dipeptide cycloprolyl-glycine is similar to piracetam by its mnemotropic selectivity
Published in Bulletin of experimental biology and medicine (01-10-1999)“…The effects of endogenous dipeptide cycloprolyl-glycine on learning and memory in the model of postconvulsive retrograde amnesia of passive avoidance response…”
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The major metabolite of dipeptide piracetam analogue GVS-111 in rat brain and its similarity to endogenous neuropeptide cyclo-L-prolylglycine
Published in European journal of drug metabolism and pharmacokinetics (01-07-1997)“…The metabolism of a new piracetam analogue, the dipeptide cognitive enhancer N-phenylacetyl-L-prolylglycine ethyl ester (GVS-111) was studied in vivo. GVS-111…”
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Postnatal stress impairs the learning of two-way avoidance task in prenatally alcoholized adult rats
Published in Bulletin of experimental biology and medicine (01-03-1997)“…Mild stress (handling and subcutaneous injection of 0.9% NaCl from postnatal day 8 through day 20) normally improves acquisition of a shuttle-box avoidance…”
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Sustained aftereffect of the amnestic action of scopolamine in rats and its elimination by piracetam
Published in Bulletin of experimental biology and medicine (01-04-1995)Get full text
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Disturbed behavior of rats suffering intrauterine hypoxia is corrected by postnatal treatment with piracetam
Published in Bulletin of experimental biology and medicine (01-01-1993)Get full text
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Nootropic properties of GABA derivatives
Published in Bulletin of experimental biology and medicine (01-02-1984)Get full text
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L-pyroglutamyl-D-alanine amide normalizes functions of the developing rat brain disturbed by antenatal alcoholization
Published in Bulletin of experimental biology and medicine (01-12-1990)Get full text
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Behavioral and electrophysiological characteristics of L-pyroglutamyl-D-alanine amide, a pyracetam analog
Published in Bulletin of experimental biology and medicine (01-11-1987)Get full text
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Antagonism between pyracetam and proline in their effect on memory
Published in Bulletin of experimental biology and medicine (01-03-1985)Get full text
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Neuropharmacologic properties of pyracetam derivatives
Published in Bulletin of experimental biology and medicine (01-12-1982)Get full text
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