Search Results - "Trnovska, J."

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    Metformin attenuates myocardium dicarbonyl stress induced by chronic hypertriglyceridemia by Malinska, H, Škop, V, Trnovska, J, Markova, I, Svoboda, P, Kazdova, L, Haluzik, M

    Published in Physiological research (01-01-2018)
    “…Reactive dicarbonyls stimulate production of advanced glycation endproducts, increase oxidative stress and inflammation and contribute to the development of…”
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    Dissecting the role of Folr1 and Folh1 genes in the pathogenesis of metabolic syndrome in spontaneously hypertensive rats by Šilhavý, J, Krijt, J, Sokolová, J, Zídek, V, Mlejnek, P, Šimáková, M, Škop, V, Trnovská, J, Oliyarnyk, O, Marková, I, Hüttl, M, Malínská, H, Kazdová, L, Liška, F, Kožich, V, Pravenec, M

    Published in Physiological research (01-01-2018)
    “…Increased levels of plasma cysteine predispose to obesity and metabolic disturbances. Our recent genetic analyses in spontaneously hypertensive rats (SHR)…”
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    Mutant Wars2 gene in spontaneously hypertensive rats impairs brown adipose tissue function and predisposes to visceral obesity by Pravenec, M, Zídek, V, Landa, V, Mlejnek, P, Šilhavý, J, Šimáková, M, Trnovská, J, Škop, V, Marková, I, Malínská, H, Hüttl, M, Kazdová, L, Bardová, K, Tauchmannová, K, Vrbacký, M, Nůsková, H, Mráček, T, Kopecký, J, Houštěk, J

    Published in Physiological research (01-01-2017)
    “…Brown adipose tissue (BAT) plays an important role in lipid and glucose metabolism in rodents and possibly also in humans. Identification of genes responsible…”
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    Hepatotoxic effects of fenofibrate in spontaneously hypertensive rats expressing human C-reactive protein by Škop, V, Trnovská, J, Oliyarnyk, O, Marková, I, Malínská, H, Kazdová, L, Zídek, V, Landa, V, Mlejnek, P, Šimáková, M, Kůdela, M, Pravenec, M, Šilhavý, J

    Published in Physiological research (01-01-2016)
    “…Dyslipidemia and inflammation play an important role in the pathogenesis of cardiovascular and liver disease. Fenofibrate has a well-known efficacy to reduce…”
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    Sterol regulatory element binding protein 2 overexpression is associated with reduced adipogenesis and ectopic fat accumulation in transgenic spontaneously hypertensive rats by Landa, V, Zídek, V, Mlejnek, P, Šimáková, M, Šilhavý, J, Trnovská, J, Kazdová, L, Pravenec, M

    Published in Physiological research (01-01-2014)
    “…It has been reported that the major function of the sterol regulatory element binding protein 2 (SREBP-2) is to activate preferentially cholesterol…”
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    Gender-related effects on substrate utilization and metabolic adaptation in hairless spontaneously hypertensive rat by Trnovská, J, Šilhavý, J, Zídek, V, Šimáková, M, Mlejnek, P, Landa, V, Eigner, S, Eigner Henke, K, Škop, V, Oliyarnyk, O, Kazdová, L, Mráček, T, Houštěk, J, Pravenec, M

    Published in Physiological research (01-01-2015)
    “…Cold exposure of rats leads to ameliorated glucose and triglyceride utilization with females displaying better adaptation to a cold environment. In the current…”
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