Search Results - "Trixl, Lukas"
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The dynamic RNA modification 5‐methylcytosine and its emerging role as an epitranscriptomic mark
Published in Wiley interdisciplinary reviews. RNA (01-01-2019)“…It is a well‐known fact that RNA is the target of a plethora of modifications which currently amount to over a hundred. The vast majority of these…”
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Getting a hold on cytosine methylation in mRNA
Published in Nature structural & molecular biology (01-05-2019)“…Cytosine methylation (m 5 C) is one of the more disputed base modifications of the epitranscriptome, mostly because current methods for detection are prone to…”
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Distinct 5-methylcytosine profiles in poly(A) RNA from mouse embryonic stem cells and brain
Published in Genome Biology (05-01-2017)“…Recent work has identified and mapped a range of posttranscriptional modifications in mRNA, including methylation of the N6 and N1 positions in adenine,…”
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Publisher Correction: RNA modification: Getting a hold on cytosine methylation in mRNA
Published in Nature structural & molecular biology (01-06-2019)“…In the version of this article initially published, the author order (Liu, J., Huang, T., Chen, W., Gu, N. & Zhang, R.) for the linked Resource (ref. 7) was…”
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RNA cytosine methyltransferase Nsun3 regulates embryonic stem cell differentiation by promoting mitochondrial activity
Published in Cellular and molecular life sciences : CMLS (01-04-2018)Get full text
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Thioguanosine Conversion Enables mRNA‐Lifetime Evaluation by RNA Sequencing Using Double Metabolic Labeling (TUC‐seq DUAL)
Published in Angewandte Chemie International Edition (20-04-2020)“…Temporal information about cellular RNA populations is essential to understand the functional roles of RNA. We have developed the hydrazine/NH4Cl/OsO4‐based…”
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A novel role for the histone acetyltransferase Hat1 in the CENP-A/CID assembly pathway in Drosophila melanogaster
Published in Nucleic acids research (18-03-2016)“…The incorporation of CENP-A into centromeric chromatin is an essential prerequisite for kinetochore formation. Yet, the molecular mechanisms governing this…”
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Bisulfite Sequencing of RNA for Transcriptome-Wide Detection of 5-Methylcytosine
Published in Methods in molecular biology (Clifton, N.J.) (2019)“…A powerful method to determine the methylation status of specific cytosine residues within RNA is bisulfite sequencing. In combination with high-throughput…”
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RNA cytosine methyltransferase Nsun3 regulates embryonic stem cell differentiation by promoting mitochondrial activity
Published in Cellular and molecular life sciences : CMLS (01-04-2018)“…Chemical modifications of RNA have been attracting increasing interest because of their impact on RNA fate and function. Therefore, the characterization of…”
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Thiouridine-to-Cytidine Conversion Sequencing (TUC-Seq) to Measure mRNA Transcription and Degradation Rates
Published in Methods in molecular biology (Clifton, N.J.) (2020)“…The study of RNA dynamics, specifically RNA transcription and decay rates, has gained increasing attention in recent years because various mechanisms have been…”
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11
Thioguanosine Conversion Enables mRNA‐Lifetime Evaluation by RNA Sequencing Using Double Metabolic Labeling (TUC‐seq DUAL)
Published in Angewandte Chemie (20-04-2020)“…Temporal information about cellular RNA populations is essential to understand the functional roles of RNA. We have developed the hydrazine/NH4Cl/OsO4‐based…”
Get full text
Journal Article