Search Results - "Trist, D.G."
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Excitatory amino acid agonists and antagonists: pharmacology and therapeutic applications
Published in Pharmaceutica acta Helvetiae (01-03-2000)“…Glutamic acid is the major excitatory neurotransmitter in the mammalian central nervous system (CNS). Specific receptors bind glutamate and some of these when…”
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N-terminal splice variants of the NMDAR1 glutamate receptor subunit: differential expression in human and monkey brain
Published in Neuroscience letters (12-06-1998)“…The distribution of the mRNA coding for the two N-terminal splice variants of the N-methyl- d-aspartate receptor 1 (NMDAR1) subunit of the glutamate NMDA…”
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The antagonism by BW A868C of PGD2 and BW245C activation of human platelet adenylate cyclase
Published in British journal of pharmacology (01-02-1989)“…1 In glycerol‐lysed human platelets, prostaglandin D2 (PGD2) and the hydantoin BW245C both activate adenylate cyclase in a biphasic manner. These activations…”
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Evidence for purinergic neurotransmission in human urinary bladder affected by interstitial cystitis
Published in The Journal of urology (01-12-1993)“…Detrusor specimens were obtained from 5 patients affected by interstitial cystitis (IC) and 5 patients with bladder carcinoma (controls). Muscle strips were…”
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NMDA NR1 subunit mRNA and glutamate NMDA-sensitive binding are differentially affected in the striatum and pre-frontal cortex of Parkinson’s disease patients
Published in Neuropharmacology (01-05-1999)“…Changes in the levels of mRNA for the NR1 subunit of the glutamate NMDA receptor and in NMDA-sensitive glutamate binding were investigated in consecutive…”
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Discrimination by benextramine between the NPY‐Y 1 receptor subtypes present in rabbit isolated vas deferens and saphenous vein
Published in British journal of pharmacology (01-05-1995)“…In order to characterize the neuropeptide Y (NPY) Y 1 receptors known to be present in rabbit isolated vas deferens and saphenous vein, the pharmacological…”
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B006 Fibrosis-related gene expression in the hypertrophied left ventricular tissue of spontaneously hypertensive rats
Published in American journal of hypertension (01-04-1998)Get full text
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1.P.79 The effect of lacidipine on atherosclerotic lesion progression in apoE knockout mice
Published in Atherosclerosis (01-10-1997)Get full text
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The mechanism of vascular protection induced by lipophilic dihydropyridine calcium antagonists
Published in Pharmacological research (1995)Get full text
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Evidence for the presence of both pre‐ and postjunctional P2‐purinoceptor subtypes in human isolated urinary bladder
Published in British journal of pharmacology (01-01-1995)“…1 In order to characterize P2‐purinoceptor(s) in human urinary bladder the contractile effects of ATP and its slowly‐hydrolyzable analogues α,β‐methylene ATP…”
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Non competitive inhibition of mGluR1a receptor by 5-chloro-8-methylthieno[2,3-b]-indole-2-carboxcylic acid
Published in Neuropharmacology (01-06-1996)Get full text
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C009 Abnormal intra- and extracellular degradation of cardiac collagen in spontaneously hypertensive rats
Published in American journal of hypertension (01-04-1998)Get full text
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Anxiolytic activity of GV 150013, a new potent and selective cholecystokinin-B (CCK-B) antagonist
Published in European neuropsychopharmacology (01-06-1996)Get full text
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Discrimination by benextramine between the NPY‐Y1 receptor subtypes present in rabbit isolated vas deferens and saphenous vein
Published in British journal of pharmacology (01-05-1995)“…1 In order to characterize the neuropeptide Y (NPY) Y1 receptors known to be present in rabbit isolated vas deferens and saphenous vein, the pharmacological…”
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Evidence for the presence of both pre‐ and postjunctional P 2 ‐purinoceptor subtypes in human isolated urinary bladder
Published in British journal of pharmacology (01-01-1995)“…In order to characterize P 2 ‐purinoceptor(s) in human urinary bladder the contractile effects of ATP and its slowly‐hydrolyzable analogues α,β‐methylene ATP…”
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Protective effect of GV150526A on the glutamate-induced changes in basal and electrically-stimulated cytosolic Ca ++ in primary cultured cerebral cortical cells
Published in Neurochemistry international (01-04-1998)“…Glutamate-induced changes in intracellular free Ca ++ concentration ([Ca ++] i) were recorded in resting and electrically-stimulated primary cultures of rat…”
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Failure of the putative neuropeptide Y antagonists, benextramine and PYX‐2, to inhibit Y 2 receptors in rat isolated prostatic vas deferens
Published in British journal of pharmacology (01-11-1995)“…The pharmacological activity of neuropeptide Y (NPY) and some analogues in inhibiting the twitch contractions induced by electrical stimulation (single pulses…”
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