Search Results - "Trisal, Meera"

Mechanisms of innate and adaptive immunity to the Pfizer-BioNTech BNT162b2 vaccine by Li, Chunfeng, Lee, Audrey, Grigoryan, Lilit, Arunachalam, Prabhu S., Scott, Madeleine K. D., Trisal, Meera, Wimmers, Florian, Sanyal, Mrinmoy, Weidenbacher, Payton A., Feng, Yupeng, Adamska, Julia Z., Valore, Erika, Wang, Yanli, Verma, Rohit, Reis, Noah, Dunham, Diane, O’Hara, Ruth, Park, Helen, Luo, Wei, Gitlin, Alexander D., Kim, Peter, Khatri, Purvesh, Nadeau, Kari C., Pulendran, Bali

“…Despite the success of the BNT162b2 mRNA vaccine, the immunological mechanisms that underlie its efficacy are poorly understood. Here we analyzed the innate…”
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Systems vaccinology of the BNT162b2 mRNA vaccine in humans by Arunachalam, Prabhu S., Scott, Madeleine K. D., Hagan, Thomas, Li, Chunfeng, Feng, Yupeng, Wimmers, Florian, Grigoryan, Lilit, Trisal, Meera, Edara, Venkata Viswanadh, Lai, Lilin, Chang, Sarah Esther, Feng, Allan, Dhingra, Shaurya, Shah, Mihir, Lee, Alexandra S., Chinthrajah, Sharon, Sindher, Sayantani B., Mallajosyula, Vamsee, Gao, Fei, Sigal, Natalia, Kowli, Sangeeta, Gupta, Sheena, Pellegrini, Kathryn, Tharp, Gregory, Maysel-Auslender, Sofia, Hamilton, Sydney, Aoued, Hadj, Hrusovsky, Kevin, Roskey, Mark, Bosinger, Steven E., Maecker, Holden T., Boyd, Scott D., Davis, Mark M., Utz, Paul J., Suthar, Mehul S., Khatri, Purvesh, Nadeau, Kari C., Pulendran, Bali

“…The emergency use authorization of two mRNA vaccines in less than a year from the emergence of SARS-CoV-2 represents a landmark in vaccinology 1 , 2 . Yet, how…”
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SREBP signaling is essential for effective B cell responses by Luo, Wei, Adamska, Julia Z., Li, Chunfeng, Verma, Rohit, Liu, Qing, Hagan, Thomas, Wimmers, Florian, Gupta, Shakti, Feng, Yupeng, Jiang, Wenxia, Zhou, Jiehao, Valore, Erika, Wang, Yanli, Trisal, Meera, Subramaniam, Shankar, Osborne, Timothy F., Pulendran, Bali

“…Our previous study using systems vaccinology identified an association between the sterol regulatory binding protein (SREBP) pathway and humoral immune…”
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Multi-omics analysis of mucosal and systemic immunity to SARS-CoV-2 after birth by Wimmers, Florian, Burrell, Allison R., Feng, Yupeng, Zheng, Hong, Arunachalam, Prabhu S., Hu, Mengyun, Spranger, Sara, Nyhoff, Lindsay E., Joshi, Devyani, Trisal, Meera, Awasthi, Mayanka, Bellusci, Lorenza, Ashraf, Usama, Kowli, Sangeeta, Konvinse, Katherine C., Yang, Emily, Blanco, Michael, Pellegrini, Kathryn, Tharp, Gregory, Hagan, Thomas, Chinthrajah, R. Sharon, Nguyen, Tran T., Grifoni, Alba, Sette, Alessandro, Nadeau, Kari C., Haslam, David B., Bosinger, Steven E., Wrammert, Jens, Maecker, Holden T., Utz, Paul J., Wang, Taia T., Khurana, Surender, Khatri, Purvesh, Staat, Mary A., Pulendran, Bali

“…The dynamics of immunity to infection in infants remain obscure. Here, we used a multi-omics approach to perform a longitudinal analysis of immunity to severe…”
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Author Correction: Systems vaccinology of the BNT162b2 mRNA vaccine in humans by Arunachalam, Prabhu S., Scott, Madeleine K. D., Hagan, Thomas, Li, Chunfeng, Feng, Yupeng, Wimmers, Florian, Grigoryan, Lilit, Trisal, Meera, Edara, Venkata Viswanadh, Lai, Lilin, Chang, Sarah Esther, Feng, Allan, Dhingra, Shaurya, Shah, Mihir, Lee, Alexandra S., Chinthrajah, Sharon, Sindher, Sayantani B., Mallajosyula, Vamsee, Gao, Fei, Sigal, Natalia, Kowli, Sangeeta, Gupta, Sheena, Pellegrini, Kathryn, Tharp, Gregory, Maysel-Auslender, Sofia, Hamilton, Sydney, Aoued, Hadj, Hrusovsky, Kevin, Roskey, Mark, Bosinger, Steven E., Maecker, Holden T., Boyd, Scott D., Davis, Mark M., Utz, Paul J., Suthar, Mehul S., Khatri, Purvesh, Nadeau, Kari C., Pulendran, Bali

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Ablation of Adar1 in myeloid cells imprints a global antiviral state in the lung and heightens early immunity against SARS-CoV-2 by Adamska, Julia Z., Verma, Rohit, Gupta, Shakti, Hagan, Thomas, Wimmers, Florian, Floyd, Katharine, Li, Qin, Valore, Erika V., Wang, Yanli, Trisal, Meera, Vilches-Moure, José G., Subramaniam, Shankar, Walkley, Carl R., Suthar, Mehul S., Li, Jin Billy, Pulendran, Bali

“…Under normal homeostatic conditions, self-double-stranded RNA (self-dsRNA) is modified by adenosine deaminase acting on RNA 1 (ADAR1) to prevent the induction…”
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Adjuvanting a subunit COVID-19 vaccine to induce protective immunity by Arunachalam, Prabhu S., Walls, Alexandra C., Golden, Nadia, Atyeo, Caroline, Fischinger, Stephanie, Li, Chunfeng, Aye, Pyone, Navarro, Mary Jane, Lai, Lilin, Edara, Venkata Viswanadh, Röltgen, Katharina, Rogers, Kenneth, Shirreff, Lisa, Ferrell, Douglas E., Wrenn, Samuel, Pettie, Deleah, Kraft, John C., Miranda, Marcos C., Kepl, Elizabeth, Sydeman, Claire, Brunette, Natalie, Murphy, Michael, Fiala, Brooke, Carter, Lauren, White, Alexander G., Trisal, Meera, Hsieh, Ching-Lin, Russell-Lodrigue, Kasi, Monjure, Christopher, Dufour, Jason, Spencer, Skye, Doyle-Meyers, Lara, Bohm, Rudolph P., Maness, Nicholas J., Roy, Chad, Plante, Jessica A., Plante, Kenneth S., Zhu, Alex, Gorman, Matthew J., Shin, Sally, Shen, Xiaoying, Fontenot, Jane, Gupta, Shakti, O’Hagan, Derek T., Van Der Most, Robbert, Rappuoli, Rino, Coffman, Robert L., Novack, David, McLellan, Jason S., Subramaniam, Shankar, Montefiori, David, Boyd, Scott D., Flynn, JoAnne L., Alter, Galit, Villinger, Francois, Kleanthous, Harry, Rappaport, Jay, Suthar, Mehul S., King, Neil P., Veesler, David, Pulendran, Bali

“…The development of a portfolio of COVID-19 vaccines to vaccinate the global population remains an urgent public health imperative 1 . Here we demonstrate the…”
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Addendum: Systems vaccinology of the BNT162b2 mRNA vaccine in humans by Arunachalam, Prabhu S, Scott, Madeleine K D, Hagan, Thomas, Li, Chunfeng, Feng, Yupeng, Wimmers, Florian, Grigoryan, Lilit, Trisal, Meera, Edara, Venkata Viswanadh, Lai, Lilin, Chang, Sarah Esther, Feng, Allan, Dhingra, Shaurya, Shah, Mihir, Lee, Alexandra S, Chinthrajah, Sharon, Sindher, Sayantani B, Mallajosyula, Vamsee, Gao, Fei, Sigal, Natalia, Kowli, Sangeeta, Gupta, Sheena, Pellegrini, Kathryn, Tharp, Gregory, Maysel-Auslender, Sofia, Hamilton, Sydney, Aoued, Hadj, Hrusovsky, Kevin, Roskey, Mark, Bosinger, Steven E, Maecker, Holden T, Boyd, Scott D, Davis, Mark M, Utz, Paul J, Suthar, Mehul S, Khatri, Purvesh, Nadeau, Kari C, Pulendran, Bali

“…[...]there was a cross-contamination of the day-1 samples obtained from participants 2049 (male) and 2051 (female), which resulted in the erroneous appearance…”
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Durability of immune responses to the BNT162b2 mRNA vaccine by Suthar, Mehul S, Arunachalam, Prabhu S, Hu, Mengyun, Reis, Noah, Trisal, Meera, Raeber, Olivia, Chinthrajah, Sharon, Davis-Gardner, Meredith E, Manning, Kelly, Mudvari, Prakriti, Boritz, Eli, Godbole, Sucheta, Henry, Amy R, Douek, Daniel C, Halfmann, Peter, Kawaoka, Yoshihiro, Boyd, Scott D, Davis, Mark M, Zarnitsyna, Veronika I, Nadeau, Kari, Pulendran, Bali

“…Antibody responses to the Pfizer-BioNTech mRNA vaccine waned substantially 6 months after the second vaccination…”
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