Search Results - "Tripodo, Claudio"

WNT signaling modulates PD-L1 expression in the stem cell compartment of triple-negative breast cancer by Castagnoli, Lorenzo, Cancila, Valeria, Cordoba-Romero, Sandra L., Faraci, Simona, Talarico, Giovanna, Belmonte, Beatrice, Iorio, Marilena V., Milani, Matteo, Volpari, Tatiana, Chiodoni, Claudia, Hidalgo-Miranda, Alfredo, Tagliabue, Elda, Tripodo, Claudio, Sangaletti, Sabina, Di Nicola, Massimo, Pupa, Serenella M.

“…Triple-negative breast cancers (TNBCs) are characterized by a poor prognosis and lack of targeted treatments, and thus, new therapeutic strategies are urgently…”
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Antibody-Fc/FcR Interaction on Macrophages as a Mechanism for Hyperprogressive Disease in Non-small Cell Lung Cancer Subsequent to PD-1/PD-L1 Blockade by Lo Russo, Giuseppe, Moro, Massimo, Sommariva, Michele, Cancila, Valeria, Boeri, Mattia, Centonze, Giovanni, Ferro, Simona, Ganzinelli, Monica, Gasparini, Patrizia, Huber, Veronica, Milione, Massimo, Porcu, Luca, Proto, Claudia, Pruneri, Giancarlo, Signorelli, Diego, Sangaletti, Sabina, Sfondrini, Lucia, Storti, Chiara, Tassi, Elena, Bardelli, Alberto, Marsoni, Silvia, Torri, Valter, Tripodo, Claudio, Colombo, Mario Paolo, Anichini, Andrea, Rivoltini, Licia, Balsari, Andrea, Sozzi, Gabriella, Garassino, Marina Chiara

“…Hyperprogression (HP), a paradoxical boost in tumor growth, was described in a subset of patients treated with immune checkpoint inhibitors (ICI). Neither…”
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Mutant p53 induces Golgi tubulo-vesiculation driving a prometastatic secretome by Capaci, Valeria, Bascetta, Lorenzo, Fantuz, Marco, Beznoussenko, Galina V., Sommaggio, Roberta, Cancila, Valeria, Bisso, Andrea, Campaner, Elena, Mironov, Alexander A., Wiśniewski, Jacek R., Ulloa Severino, Luisa, Scaini, Denis, Bossi, Fleur, Lees, Jodi, Alon, Noa, Brunga, Ledia, Malkin, David, Piazza, Silvano, Collavin, Licio, Rosato, Antonio, Bicciato, Silvio, Tripodo, Claudio, Mantovani, Fiamma, Del Sal, Giannino

“…TP53 missense mutations leading to the expression of mutant p53 oncoproteins are frequent driver events during tumorigenesis. p53 mutants promote tumor growth,…”
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C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation by Bulla, Roberta, Tripodo, Claudio, Rami, Damiano, Ling, Guang Sheng, Agostinis, Chiara, Guarnotta, Carla, Zorzet, Sonia, Durigutto, Paolo, Botto, Marina, Tedesco, Francesco

“…Complement C1q is the activator of the classical pathway. However, it is now recognized that C1q can exert functions unrelated to complement activation. Here…”
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How I diagnose and treat splenic lymphomas by Iannitto, Emilio, Tripodo, Claudio

“…The incidental finding of an isolated splenomegaly during clinical assessment of patients evaluated for unrelated causes has become increasingly frequent…”
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Dynamics of complement activation in aHUS and how to monitor eculizumab therapy by Noris, Marina, Galbusera, Miriam, Gastoldi, Sara, Macor, Paolo, Banterla, Federica, Bresin, Elena, Tripodo, Claudio, Bettoni, Serena, Donadelli, Roberta, Valoti, Elisabetta, Tedesco, Francesco, Amore, Alessandro, Coppo, Rosanna, Ruggenenti, Piero, Gotti, Eliana, Remuzzi, Giuseppe

“…Atypical hemolytic-uremic syndrome (aHUS) is associated with genetic complement abnormalities/anti–complement factor H antibodies, which paved the way to…”
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SARS-CoV2 vertical transmission with adverse effects on the newborn revealed through integrated immunohistochemical, electron microscopy and molecular analyses of Placenta by Facchetti, Fabio, Bugatti, Mattia, Drera, Emma, Tripodo, Claudio, Sartori, Enrico, Cancila, Valeria, Papaccio, Marta, Castellani, Roberta, Casola, Stefano, Boniotti, Maria Beatrice, Cavadini, Patrizia, Lavazza, Antonio

“… The occurrence of trans-placental transmission of severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) infection remains highly debated. Placental…”
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Unjamming overcomes kinetic and proliferation arrest in terminally differentiated cells and promotes collective motility of carcinoma by Palamidessi, Andrea, Malinverno, Chiara, Frittoli, Emanuela, Corallino, Salvatore, Barbieri, Elisa, Sigismund, Sara, Beznoussenko, Galina V., Martini, Emanuele, Garre, Massimiliano, Ferrara, Ines, Tripodo, Claudio, Ascione, Flora, Cavalcanti-Adam, Elisabetta A., Li, Qingsen, Di Fiore, Pier Paolo, Parazzoli, Dario, Giavazzi, Fabio, Cerbino, Roberto, Scita, Giorgio

“…During wound repair, branching morphogenesis and carcinoma dissemination, cellular rearrangements are fostered by a solid-to-liquid transition, known as…”
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Compromised nuclear envelope integrity drives TREX1-dependent DNA damage and tumor cell invasion by Nader, Guilherme Pedreira de Freitas, Agüera-Gonzalez, Sonia, Routet, Fiona, Gratia, Matthieu, Maurin, Mathieu, Cancila, Valeria, Cadart, Clotilde, Palamidessi, Andrea, Ramos, Rodrigo Nalio, San Roman, Mabel, Gentili, Matteo, Yamada, Ayako, Williart, Alice, Lodillinsky, Catalina, Lagoutte, Emilie, Villard, Catherine, Viovy, Jean-Louis, Tripodo, Claudio, Galon, Jérôme, Scita, Giorgio, Manel, Nicolas, Chavrier, Philippe, Piel, Matthieu

“…Although mutations leading to a compromised nuclear envelope cause diseases such as muscular dystrophies or accelerated aging, the consequences of mechanically…”
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Neutrophil extracellular traps mediate transfer of cytoplasmic neutrophil antigens to myeloid dendritic cells toward ANCA induction and associated autoimmunity by Sangaletti, Sabina, Tripodo, Claudio, Chiodoni, Claudia, Guarnotta, Carla, Cappetti, Barbara, Casalini, Patrizia, Piconese, Silvia, Parenza, Mariella, Guiducci, Cristiana, Vitali, Caterina, Colombo, Mario P.

“…Antineutrophil cytoplasmic antibodies (ANCAs) target proteins normally retained within neutrophils, indicating that cell death is involved in the autoimmunity…”
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Myeloid cell heterogeneity in lung cancer: implication for immunotherapy by Sangaletti, Sabina, Ferrara, Roberto, Tripodo, Claudio, Garassino, Marina Chiara, Colombo, Mario Paolo

“…Lung is a specialized tissue where metastases from primary lung tumors takeoff and those originating from extra-pulmonary sites land. One commonality…”
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Butyrate, a postbiotic of intestinal bacteria, affects pancreatic cancer and gemcitabine response in in vitro and in vivo models by Panebianco, Concetta, Villani, Annacandida, Pisati, Federica, Orsenigo, Fabrizio, Ulaszewska, Marynka, Latiano, Tiziana Pia, Potenza, Adele, Andolfo, Annapaola, Terracciano, Fulvia, Tripodo, Claudio, Perri, Francesco, Pazienza, Valerio

“…Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer. The characteristic excessive stromatogenesis accompanying the growth of this tumor is believed…”
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Rheostatic Functions of Mast Cells in the Control of Innate and Adaptive Immune Responses by Frossi, Barbara, Mion, Francesca, Tripodo, Claudio, Colombo, Mario P, Pucillo, Carlo E

“…Mast cells are evolutionarily ancient cells, endowed with a unique developmental, phenotypic, and functional plasticity. They are resident cells that…”
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Post-mortem findings in vaccine-induced thrombotic thombocytopenia by Pomara, Cristoforo, Sessa, Francesco, Ciaccio, Marcello, Dieli, Francesco, Esposito, Massimiliano, Garozzo, Sebastiano Fabio, Giarratano, Antonino, Prati, Daniele, Rappa, Francesca, Salerno, Monica, Tripodo, Claudio, Zamboni, Paolo, Mannucci, Pier Mannuccio

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Inhibition of DNA damage response at telomeres improves the detrimental phenotypes of Hutchinson–Gilford Progeria Syndrome by Aguado, Julio, Sola-Carvajal, Agustin, Cancila, Valeria, Revêchon, Gwladys, Ong, Peh Fern, Jones-Weinert, Corey Winston, Wallén Arzt, Emelie, Lattanzi, Giovanna, Dreesen, Oliver, Tripodo, Claudio, Rossiello, Francesca, Eriksson, Maria, d’Adda di Fagagna, Fabrizio

“…Hutchinson–Gilford progeria syndrome (HGPS) is a genetic disorder characterized by premature aging features. Cells from HGPS patients express progerin, a…”
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Drp1 Controls Effective T Cell Immune-Surveillance by Regulating T Cell Migration, Proliferation, and cMyc-Dependent Metabolic Reprogramming by Simula, Luca, Pacella, Ilenia, Colamatteo, Alessandra, Procaccini, Claudio, Cancila, Valeria, Bordi, Matteo, Tregnago, Claudia, Corrado, Mauro, Pigazzi, Martina, Barnaba, Vincenzo, Tripodo, Claudio, Matarese, Giuseppe, Piconese, Silvia, Campello, Silvia

“…Mitochondria are key players in the regulation of T cell biology by dynamically responding to cell needs, but how these dynamics integrate in T cells is still…”
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Pseudotemporal ordering of spatial lymphoid tissue microenvironment profiles trails Unclassified DLBCL at the periphery of the follicle by Tripodo, Claudio, Bertolazzi, Giorgio, Cancila, Valeria, Morello, Gaia, Iannitto, Emilio

“…We have established a pseudotemporal ordering for the transcriptional signatures of distinct microregions within reactive lymphoid tissues, namely germinal…”
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IRSp53 controls plasma membrane shape and polarized transport at the nascent lumen in epithelial tubules by Bisi, Sara, Marchesi, Stefano, Rizvi, Abrar, Carra, Davide, Beznoussenko, Galina V., Ferrara, Ines, Deflorian, Gianluca, Mironov, Alexander, Bertalot, Giovanni, Pisati, Federica, Oldani, Amanda, Cattaneo, Angela, Saberamoli, Ghazaleh, Pece, Salvatore, Viale, Giuseppe, Bachi, Angela, Tripodo, Claudio, Scita, Giorgio, Disanza, Andrea

“…It is unclear whether the establishment of apical–basal cell polarity during the generation of epithelial lumens requires molecules acting at the plasma…”
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Unsupervised representation learning of chromatin images identifies changes in cell state and tissue organization in DCIS by Zhang, Xinyi, Venkatachalapathy, Saradha, Paysan, Daniel, Schaerer, Paulina, Tripodo, Claudio, Uhler, Caroline, Shivashankar, G. V.

“…Ductal carcinoma in situ (DCIS) is a pre-invasive tumor that can progress to invasive breast cancer, a leading cause of cancer death. We generate a large-scale…”
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Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4 by Todaro, Matilde, Alea, Mileidys Perez, Di Stefano, Anna B, Cammareri, Patrizia, Vermeulen, Louis, Iovino, Flora, Tripodo, Claudio, Russo, Antonio, Gulotta, Gaspare, Medema, Jan Paul, Stassi, Giorgio

“…A novel paradigm in tumor biology suggests that cancer growth is driven by stem-like cells within a tumor. Here, we describe the identification and…”
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