Search Results - "Triplet, Erin M"
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The thrombin receptor links brain derived neurotrophic factor to neuron cholesterol production, resiliency and repair after spinal cord injury
Published in Neurobiology of disease (01-05-2021)“…Despite concerted efforts to identify CNS regeneration strategies, an incomplete understanding of how the needed molecular machinery is regulated limits…”
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Statin use is associated with reduced motor recovery after spinal cord injury
Published in Spinal cord series and cases (03-02-2021)“…Study design We completed retrospective analysis of statin use in individuals with neurologically significant spinal cord injury in a historical cohort study…”
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Dietary influence on central nervous system myelin production, injury, and regeneration
Published in Biochimica et biophysica acta. Molecular basis of disease (01-07-2020)“…Oligodendrocytes not only produce myelin to facilitate nerve impulse conduction, but are also essential metabolic partners of the axon. Oligodendrocyte loss…”
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A tale of two cohorts: Differing outcomes in infantile‐onset focal epilepsy
Published in Epilepsia (Copenhagen) (01-04-2022)“…Objective Infants with focal‐onset epilepsy are an understudied population, requiring additional evaluation for clinical assessment and prognostication. Our…”
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The thrombin receptor modulates astroglia‐neuron trophic coupling and neural repair after spinal cord injury
Published in Glia (01-09-2021)“…Excessive activation of the thrombin receptor, protease activated receptor 1 (PAR1) is implicated in diverse neuropathologies from neurodegenerative conditions…”
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Blocking the Thrombin Receptor Promotes Repair of Demyelinated Lesions in the Adult Brain
Published in The Journal of neuroscience (12-02-2020)“…Myelin loss limits neurological recovery and myelin regeneration and is critical for restoration of function. We recently discovered that global knock-out of…”
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Blocking Kallikrein 6 promotes developmental myelination
Published in Glia (01-03-2022)“…Kallikrein related peptidase 6 (Klk6) is a secreted serine protease highly expressed in oligodendrocytes and implicated in demyelinating conditions. To gain…”
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