Search Results - "Tripathy, Sandeep K"

Acquisition of activation receptor ligand by trogocytosis renders NK cells hyporesponsive by Miner, Cathrine A, Giri, Tusar K, Meyer, Claire E, Shabsovich, Mark, Tripathy, Sandeep K

“…Because NK cells secrete cytotoxic granules and cytokines that can destroy surrounding cells and help shape the subsequent immune response, they must be kept…”
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Continuous engagement of a self-specific activation receptor induces NK cell tolerance by Tripathy, Sandeep K, Keyel, Peter A, Yang, Liping, Pingel, Jeanette T, Cheng, Tammy P, Schneeberger, Achim, Yokoyama, Wayne M

“…Natural killer (NK) cell tolerance mechanisms are incompletely understood. One possibility is that they possess self-specific activation receptors that result…”
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Chronic Ly49H Receptor Engagement in vivo Decreases NK Cell Response to Stimulation Through ITAM-Dependent and Independent Pathways Both in vitro and in vivo by Key, Phillip N, Germino, Joe, Yang, Liping, Piersma, Sytse J, Tripathy, Sandeep K

“…Natural killer (NK) cells play an important role in the innate immune response. The summation of activation and inhibitory signals delivered through cell…”
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Expression of the Inhibitory Receptor NKG2a Correlates with Increased Liver and Splenic NK Cell Response to Activation Receptor Engagement by Meyer, Claire, Key, Phillip, Tripathy, Sandeep K

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Expression of m157, a Murine Cytomegalovirus-Encoded Putative Major Histocompatibility Class I (MHC-I)-Like Protein, Is Independent of Viral Regulation of Host MHC-I by TRIPATHY, Sandeep K, SMITH, Hamish R. C, HOLROYD, Erika A, PINGEL, Jeanette T, YOKOYAMA, Wayne M

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Glycolytic requirement for NK cell cytotoxicity and cytomegalovirus control by Mah, Annelise Y, Rashidi, Armin, Keppel, Molly P, Saucier, Nermina, Moore, Emily K, Alinger, Joshua B, Tripathy, Sandeep K, Agarwal, Sandeep K, Jeng, Emily K, Wong, Hing C, Miller, Jeffrey S, Fehniger, Todd A, Mace, Emily M, French, Anthony R, Cooper, Megan A

“…NK cell activation has been shown to be metabolically regulated in vitro; however, the role of metabolism during in vivo NK cell responses to infection is…”
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Novel Mouse Model of Murine Cytomegalovirus-Induced Adaptive NK Cells by Jensen, Isaac J, Martin, Matthew D, Tripathy, Sandeep K, Badovinac, Vladimir P

“…NK cells are important mediators of viral control with the capacity to form adaptive immune features following infection. However, studies of infection-induced…”
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Activation receptor-induced tolerance of mature NK cells in vivo requires signaling through the receptor and is reversible by Bolanos, Fred D, Tripathy, Sandeep K

“…NK cell responses are determined by signals received through activating and inhibitory cell surface receptors. Ly49H is an NK cell-specific activating receptor…”
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Viral infection transiently reverses activation receptor‐mediated NK cell hyporesponsiveness in an MHC class I‐independent mechanism by Mazumdar, Budhaditya, Bolanos, Fred D., Tripathy, Sandeep K.

“…Continuous engagement of the Ly49H activating receptor with its ligand (m157) in a transgenic mouse expressing m157 (m157‐Tg) results in hyporesponsiveness of…”
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Stable Delivery of Physiologic Levels of Recombinant Erythropoietin to the Systemic Circulation by Intramuscular Injection of Replication-Defective Adenovirus by Tripathy, S K, Goldwasser, E, Lu, M M, Barr, E, Leiden, J M

“…A number of inherited and acquired serum protein deficiencies including hemophilias A and B, diabetes mellitus, and the erythropoietin-responsive anemias are…”
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Expression of the inhibitory receptor NKG2A correlates with increased liver and splenic NK cell response to activating receptor engagement by Meyer, Claire E., Key, Phillip N., Zhu, Toby, Shabsovich, Mark, Ni, Ann, Tripathy, Sandeep K.

“…Introduction Natural killer (NK) cells play a critical role in the innate immune response to viruses and tumors, and comprise a large proportion of the hepatic…”
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Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors by Tripathy, Sandeep K, Black, Hugh B, Goldwasser, Eugene, Leiden, Jeffrey M

“…The use of replication-defective adenoviruses (RDAd) for human gene therapy has been limited by host immune responses that result in transient recombinant gene…”
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Novel mouse model of MCMV-induced adaptive NK cells by Jensen, Isaac J, Martin, Matthew D, Tripathy, Sandeep K, Badovinac, Vladimir P, Farber, Donna L

“…NK cells are important mediators of viral control with the capacity to form adaptive immune features following infection. However, studies of infection-induced…”
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272 - Expression of the Inhibitory Receptor NKG2a Correlates with Increased Liver and Splenic NK Cell Response to Activation Receptor Engagement by Meyer, Claire, Key, Phillip, Tripathy, Sandeep K.

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Acquisition of activation receptor ligand by trogocytosis renders natural killercells hyporesponsive by Miner, Cathrine A., Giri, Tusar K., Meyer, Claire E., Shabsovich, Mark, Tripathy, Sandeep K.

“…Since natural killer (NK) cells secrete cytotoxic granules and cytokines which can destroy surrounding cells and help shape the subsequent immune response,…”
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Activation receptor-induced tolerance of mature natural killer cells in vivo requires signaling through the receptor and is reversible by Bolanos, Fred D., Tripathy, Sandeep K.

“…Natural killer (NK) cell responses are determined by signals received through activating and inhibitory cell surface receptors. Ly49H is an NK cell-specific…”
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Expression of the inhibitory receptor NKG2A correlates with increased liver and splenic NK cell response to activating receptor engagement: Liver NK cell responses correlate with NKG2A levels by Meyer, Claire E., Key, Phillip N., Zhu, Toby, Shabsovich, Mark, Ni, Ann, Tripathy, Sandeep K.

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Long-Term Expression of Erythropoietin in the Systemic Circulation of Mice after Intramuscular Injection of a Plasmid DNA Vector by Tripathy, Sandeep K., Svensson, Eric C., Black, Hugh B., Goldwasser, Eugene, Margalith, Michal, Hobart, Peter M., Leiden, Jeffrey M.

“…Erythropoietin (Epo)-responsive anemia is a common and debilitating complication of chronic renal failure and human immunodeficiency virus infection. Current…”
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Efficient catheter-mediated gene transfer into the heart using replication-defective adenovirus by Barr, E, Carroll, J, Kalynych, A M, Tripathy, S K, Kozarsky, K, Wilson, J M, Leiden, J M

“…The ability to express recombinant genes in the coronary vasculature and the myocardium holds promise for the treatment of a number of acquired and inherited…”
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Long-term erythropoietin expression in rodents and non-human primates following intramuscular injection of a replication-defective adenoviral vector by Svensson, E C, Black, H B, Dugger, D L, Tripathy, S K, Goldwasser, E, Hao, Z, Chu, L, Leiden, J M

“…Erythropoietin (Epo)-responsive anemia is a debilitating complication of chronic renal failure and human immunodeficiency virus (HIV) infection that effects…”
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