Search Results - "Tripathi, Rakshamani"

Male germ cell apoptosis: regulation and biology by Shaha, Chandrima, Tripathi, Rakshamani, Mishra, Durga Prasad

“…Cellular apoptosis appears to be a constant feature in the adult testis and during early development. This is essential because mammalian spermatogenesis is a…”
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Combating acquired resistance to MAPK inhibitors in melanoma by targeting Abl1/2-mediated reactivation of MEK/ERK/MYC signaling by Tripathi, Rakshamani, Liu, Zulong, Jain, Aditi, Lyon, Anastasia, Meeks, Christina, Richards, Dana, Liu, Jinpeng, He, Daheng, Wang, Chi, Nespi, Marika, Rymar, Andrey, Wang, Peng, Wilson, Melissa, Plattner, Rina

“…Metastatic melanoma remains an incurable disease for many patients due to the limited success of targeted and immunotherapies. BRAF and MEK inhibitors reduce…”
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Anticancer activity of a combination of cisplatin and fisetin in embryonal carcinoma cells and xenograft tumors by Tripathi, Rakshamani, Samadder, Tanmoy, Gupta, Sarika, Surolia, Avadhesha, Shaha, Chandrima

“…Use of chemotherapeutic drug cisplatin is limited because of its toxicity. Therefore, efforts continue for the discovery of novel combination therapies with…”
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EnABLing Cathepsin-Driven Melanoma Metastasis by Tripathi, Rakshamani, Plattner, Rina

“…Metastatic melanoma remains incurable for many due to its aggressive nature. Secreted cathepsins promote metastasis by cleaving matrix and activating…”
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Modulation of oxidative damage by natural products by Tripathi, Rakshamani, Mohan, H., Kamat, J.P.

“…Using rat liver membrane as a model system, modulation of oxidative damage induced by pathophysiological agents such as photosensitization and radiation was…”
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Beclin‐1–p53 interaction is crucial for cell fate determination in embryonal carcinoma cells by Tripathi, Rakshamani, Ash, Dipankar, Shaha, Chandrima

“…Emerging interest on the interrelationship between the apoptotic and autophagy pathways in the context of cancer chemotherapy is providing exciting…”
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Corrigendum to "Apoptotic effects of mahanine on human leukemic cells are mediated through crosstalk between Apo-1/Fas signaling and the Bid protein and via mitochondrial pathways" [Biochem. Pharmacol. 79 (2010) 361-372] by Bhattacharya, Kaushik, Samanta, Suman K, Tripathi, Rakshamani, Mallick, Asish, Chandra, Sarmila, Pal, Bikas C, Shaha, Chandrima, Mandal, Chitra

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Abl and Arg mediate cysteine cathepsin secretion to facilitate melanoma invasion and metastasis by Tripathi, Rakshamani, Fiore, Leann S, Richards, Dana L, Yang, Yuchen, Liu, Jinpeng, Wang, Chi, Plattner, Rina

“…The incidence of melanoma is increasing, particularly in young women, and the disease remains incurable for many because of its aggressive, metastatic nature…”
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Enabling Tumor Growth and Progression: Recent Progress in Unraveling the Functions of ABL Kinases in Solid Tumor Cells by Tripathi, Rakshamani, Liu, Zulong, Plattner, Rina

“…Purpose of Review The goal of this review is to summarize our current knowledge regarding how ABL family kinases are activated in solid tumors and impact on…”
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Male germ cell development: turning on the apoptotic pathways by Tripathi, Rakshamani, Mishra, Durga Prasad, Shaha, Chandrima

“…Abstract From the viewpoint of improving germ cell production and treatment of testicular cancers, understanding the control of testicular cell death is of…”
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Abl kinase regulation by BRAF/ERK and cooperation with Akt in melanoma by Jain, A, Tripathi, R, Turpin, C P, Wang, C, Plattner, R

“…The melanoma incidence continues to increase, and the disease remains incurable for many due to its metastatic nature and high rate of therapeutic resistance…”
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ABL1/2 and DDR1 Drive MEKi Resistance in NRAS-Mutant Melanomas by Stabilizing RAF/MYC/ETS1 and Promoting RAF Homodimerization by Lyon, Anastasia, Tripathi, Rakshamani, Meeks, Christina, He, Daheng, Wu, Yuanyuan, Liu, Jinpeng, Wang, Chi, Chen, Jing, Zhu, Haining, Mukherjee, Sujata, Ganguly, Saptadwipa, Plattner, Rina

“…Melanomas harboring mutations are a particularly aggressive and deadly subtype. If patients cannot tolerate or the melanomas are insensitive to immune…”
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Apoptotic effects of mahanine on human leukemic cells are mediated through crosstalk between Apo-1/Fas signaling and the Bid protein and via mitochondrial pathways by Bhattacharya, Kaushik, Samanta, Suman K., Tripathi, Rakshamani, Mallick, Asish, Chandra, Sarmila, Pal, Bikas C., Shaha, Chandrima, Mandal, Chitra

“…Apo-1 (Fas/CD95), a cell surface receptor, triggers apoptosis after binding to its physiological ligand, Apo-1L (FasL/CD95L). This study reports that mahanine,…”
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Mahanine, a novel mitochondrial complex-III inhibitor induces G0/G1 arrest through redox alteration-mediated DNA damage response and regresses glioblastoma multiforme by Bhattacharya, Kaushik, Bag, Arup K, Tripathi, Rakshamani, Samanta, Suman K, Pal, Bikas C, Shaha, Chandrima, Mandal, Chitra

“…The Electron transport chain (ETC) is responsible for oxidative phosphorylation-mediated mitochondrial respiration. Here we wanted to address the…”
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Andrographis paniculata : an emerging radioprotective agent for membrane proteins by Rakshamani Tripathi, Kamat, J. P

“…This chapter describes the ability of (Ap) to prevent radiation-induced oxidative damage to proteins in experiments on rat liver mitochondria at high radiation…”
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Free radical induced damages to rat liver subcellular organelles: inhibition by Andrographis paniculata extract by Tripathi, Rakshamani, Kamat, J P

“…Aqueous extract of Andrographis paniculata was examined for antioxidant activity using rat liver subcellular organelles as model systems. The study deals with…”
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