Search Results - "Triolo, Taylor M."

Lessons and gaps in the prediction and prevention of type 1 diabetes by Mameli, Chiara, Triolo, Taylor M., Chiarelli, Francesco, Rewers, Marian, Zuccotti, Gianvincenzo, Simmons, Kimber M.

“…Type 1 diabetes (T1D) is a serious chronic autoimmune condition. Even though the root cause of T1D development has yet to be determined, enough is known about…”
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Lessons from Human Islet Transplantation Inform Stem Cell-Based Approaches in the Treatment of Diabetes by Triolo, Taylor M, Bellin, Melena D

“…Diabetes mellitus is characterized by the body's inability to control blood glucose levels within a physiological range due to loss and/or dysfunction of…”
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Longitudinal Quality of Life and Glycemic Outcomes of Total Pancreatectomy With Islet Autotransplantation in Children With Chronic Pancreatitis Followed in a Pediatric Multidisciplinary Pancreas Clinic by Khatter, Neil J., Hum, Stephanie W., Mark, Jacob A., Forlenza, Gregory, Triolo, Taylor M.

“…ABSTRACT Background Total pancreatectomy with islet autotransplantation (TPIAT) is a potentially curative treatment for patients with chronic pancreatitis (CP)…”
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Development of a standardized MRI protocol for pancreas assessment in humans by Virostko, John, Craddock, Richard C, Williams, Jonathan M, Triolo, Taylor M, Hilmes, Melissa A, Kang, Hakmook, Du, Liping, Wright, Jordan J, Kinney, Mara, Maki, Jeffrey H, Medved, Milica, Waibel, Michaela, Kay, Thomas W H, Thomas, Helen E, Greeley, Siri Atma W, Steck, Andrea K, Moore, Daniel J, Powers, Alvin C

“…Magnetic resonance imaging (MRI) has detected changes in pancreas volume and other characteristics in type 1 and type 2 diabetes. However, differences in MRI…”
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Stem-Cell-Derived β-Like Cells with a Functional PTPN2 Knockout Display Increased Immunogenicity by Triolo, Taylor M, Matuschek, J Quinn, Castro-Gutierrez, Roberto, Shilleh, Ali H, Williams, Shane P M, Hansen, Maria S, McDaniel, Kristen, Barra, Jessie M, Michels, Aaron, Russ, Holger A

“…Type 1 diabetes is a polygenic disease that results in an autoimmune response directed against insulin-producing beta cells. is a known high-risk type 1…”
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Diabetic Subjects Diagnosed Through the Diabetes Prevention Trial-Type 1 (DPT-1) Are Often Asymptomatic With Normal A1C at Diabetes Onset by Triolo, Taylor M, Chase, H. Peter, Barker, Jennifer M

“…OBJECTIVE: Upon diagnosis of type 1 diabetes, patients are usually symptomatic, and many have ketoacidosis. Screening for islet autoantibodies (IAs) has been…”
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Proinsulin:C-peptide ratio trajectories over time in relatives at increased risk of progression to type 1 diabetes by Triolo, Taylor M., Pyle, Laura, Seligova, Sona, Yu, Liping, Simmons, Kimber, Gottlieb, Peter, Evans-Molina, Carmella, Steck, Andrea K.

“…Biomarkers are needed to characterize heterogeneity within populations at risk for type 1 diabetes. The ratio of proinsulin to C-peptide (PI:C ratio), has been…”
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161-LB: Diagnosis and Treatment of Diabetes Mellitus in Pediatric Patients with Pancreatitis Followed in a Multidisciplinary Clinic by VARGAS, ELIZABETH, MARK, JACOB, FORLENZA, GREGORY P., TRIOLO, TAYLOR M.

“…Children with recurring acute or chronic pancreatitis are at risk for pancreatitis related diabetes mellitus (DM). Pancreatic endocrine and exocrine concerns…”
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1617-P: Association of High-Affinity Autoantibodies with High-Risk HLA Haplotypes by TRIOLO, TAYLOR M., PYLE, LAURA, YU, LIPING, GOTTLIEB, PETER, STECK, ANDREA

“…Electrochemiluminescence (ECL) assays are high-affinity autoantibodies (Abs) that are more specific than radiobinding assay (RBA) Abs for the prediction of…”
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Association of High-Affinity Autoantibodies With Type 1 Diabetes High-Risk HLA Haplotypes by Triolo, Taylor M, Pyle, Laura, Broncucia, Hali, Armstrong, Taylor, Yu, Liping, Gottlieb, Peter A, Steck, Andrea K

“…Electrochemiluminescence (ECL) assays are high-affinity autoantibody (Ab) tests that are more specific than Abs detected by traditional radiobinding assays…”
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Increased Technology Use Associated With Lower A1C in a Large Pediatric Clinical Population by Alonso, G Todd, Triolo, Taylor M, Akturk, Halis Kaan, Pauley, Meghan E, Sobczak, Marisa, Forlenza, Gregory P, Sakamoto, Casey, Pyle, Laura, Frohnert, Brigitte I

“…While continuous glucose monitors (CGMs), insulin pumps, and hybrid closed-loop (HCL) systems each improve glycemic control in type 1 diabetes, it is unclear…”
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1125-P: Do Non-HLA Genes Contribute to Age of Type 1 Diabetes Onset in Monozygotic Twins? by TRIOLO, TAYLOR M., DONG, FRAN, BRONCUCIA, HALI C., ONENGUT-GUMUSCU, SUNA, STECK, ANDREA, RICH, STEPHEN S.

“…Development of islet autoimmunity (IA) and type 1 diabetes (T1D) are associated with high-risk HLA class II loci as well as non-HLA genes. Monozygotic (MZ)…”
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Genetic Associations with C-peptide Levels before Type 1 Diabetes Diagnosis in At-Risk Relatives by Triolo, Taylor M, Parikh, Hemang M, Tosur, Mustafa, Ferrat, Lauric, You, Lu, Gottlieb, Peter A, Oram, Richard A, Onengut-Gumuscu, Suna, Krischer, Jeffrey P, Rich, Stephen S, Steck, Andrea K, Redondo, Maria J

“…We sought to determine whether the type 1 diabetes genetic risk score-2 (T1D-GRS2) and single nucleotide polymorphisms (SNPs) are associated with C-peptide…”
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1254-P: Genetic Prediction of C-Peptide Trajectory before Type 1 Diabetes Diagnosis in TrialNet by TRIOLO, TAYLOR M., PARIKH, HEMANG M., TOSUR, MUSTAFA, GOTTLIEB, PETER, ORAM, RICHARD A., ONENGUT-GUMUSCU, SUNA, KRISCHER, JEFFREY, RICH, STEPHEN S., STECK, ANDREA, REDONDO, MARIA J.

“…Modeling the course of C-peptide decline in autoantibody (Ab) positive individuals is important for type 1 diabetes (T1D) prediction and implementation of T1D…”
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193-LB: Differentiation of PTPN2 Knockout Pluripotent Stem Cells into Stem-Cell–Derived ß-Like Cells Leads to Increased Stimulation of Diabetogenic TCR T Cell Transductants by MATUSCHEK, JULIA Q., RUSS, HOLGER A., TRIOLO, TAYLOR M., MICHELS, AARON W., MCDANIEL, KRISTEN, HANSEN, MARIA S., WILLIAMS, SHANE, CASTRO-GUTIERREZ, ROBERTO, SHILLEH, ALI

“…Type 1 diabetes (T1D) is an autoimmune disease marked by permanent loss of insulin-producing pancreatic β cells. Genome wide association studies have…”
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ENTPD3 Marks Mature Stem Cell-Derived β-Cells Formed by Self-Aggregation In Vitro by Docherty, Fiona M, Riemondy, Kent A, Castro-Gutierrez, Roberto, Dwulet, JaeAnn M, Shilleh, Ali H, Hansen, Maria S, Williams, Shane P M, Armitage, Lucas H, Santostefano, Katherine E, Wallet, Mark A, Mathews, Clayton E, Triolo, Taylor M, Benninger, Richard K P, Russ, Holger A

“…Stem cell-derived β-like cells (sBC) carry the promise of providing an abundant source of insulin-producing cells for use in cell replacement therapy for…”
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216-LB: Genetic Influences on Beta-Cell Function before Type 1 Diabetes Diagnosis by TRIOLO, TAYLOR M., PARIKH, HEMANG M., TOSUR, MUSTAFA, FERRAT, LAURIC A., YOU, LU, GOTTLIEB, PETER, ORAM, RICHARD A., ONENGUT-GUMUSCU, SUNA, KRISCHER, JEFFREY, RICH, STEPHEN S., STECK, ANDREA, REDONDO, MARIA J.

“…Autoimmune loss of beta-cell function (measured by C-peptide) is the hallmark of type 1 diabetes (T1D) targeted by interventions that aim to prevent T1D or its…”
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Additional Autoimmune Disease Found in 33% of Patients at Type 1 Diabetes Onset by Triolo, Taylor M, Armstrong, Taylor K, McFann, Kim, Yu, Liping, Rewers, Marian J, Klingensmith, Georgeanna J, Eisenbarth, George S, Barker, Jennifer M

“…OBJECTIVE: We sought to define the prevalence of nonislet, organ-specific autoantibodies at diagnosis of type 1 diabetes and to determine the prevalence of…”
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Longitudinal Assessment of Pancreas Volume by MRI Predicts Progression to Stage 3 Type 1 Diabetes by Virostko, John, Wright, Jordan J, Williams, Jonathan M, Hilmes, Melissa A, Triolo, Taylor M, Broncucia, Hali, Du, Liping, Kang, Hakmook, Nallaparaju, Shreya, Valencia, Leah Galvez, Reyes, Demetra, Hammel, Brenna, Russell, William E, Philipson, Louis H, Waibel, Michaela, Kay, Thomas W H, Thomas, Helen E, Greeley, Siri Atma W, Steck, Andrea K, Powers, Alvin C, Moore, Daniel J

“…This multicenter prospective cohort study compared pancreas volume as assessed by MRI, metabolic scores derived from oral glucose tolerance testing (OGTT), and…”
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Etiology of Insulin Resistance in Youth with Type 2 Diabetes by Cree-Green, Melanie, Triolo, Taylor M., Nadeau, Kristen J.

“…Type 2 diabetes (T2DM), historically an adult disease, is now increasingly prevalent in obese youth. Poor diet and increased sedentary behavior contribute to…”
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