Search Results - "Trinh, Cong"
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Exceptional solvent tolerance in Yarrowia lipolytica is enhanced by sterols
Published in Metabolic engineering (01-07-2019)“…Green organic solvents such as ionic liquids (ILs) have versatile use but are inhibitory to microbes even at low concentrations of 0.5–1.0% (v/v) ILs. We…”
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Modular design: Implementing proven engineering principles in biotechnology
Published in Biotechnology advances (15-11-2019)“…Modular design is at the foundation of contemporary engineering, enabling rapid, efficient, and reproducible construction and maintenance of complex systems…”
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Understanding Functional Roles of Native Pentose-Specific Transporters for Activating Dormant Pentose Metabolism in Yarrowia lipolytica
Published in Applied and environmental microbiology (01-02-2018)“…Pentoses, including xylose and arabinose, are the second most prevalent sugars in lignocellulosic biomass that can be harnessed for biological conversion…”
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Towards renewable flavors, fragrances, and beyond
Published in Current opinion in biotechnology (01-02-2020)“…[Display omitted] •Microbial cell factories offer sustainable and renewable production of natural esters.•Modular cell design enables rapid construction of…”
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Activating and Elucidating Metabolism of Complex Sugars in Yarrowia lipolytica
Published in Applied and environmental microbiology (15-02-2016)“…The oleaginous yeast Yarrowia lipolytica is an industrially important host for production of organic acids, oleochemicals, lipids, and proteins with broad…”
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6
Multiobjective strain design: A framework for modular cell engineering
Published in Metabolic engineering (01-01-2019)“…Diversity of cellular metabolism can be harnessed to produce a large space of molecules. However, development of optimal strains with high product titers,…”
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Enhanced guide-RNA design and targeting analysis for precise CRISPR genome editing of single and consortia of industrially relevant and non-model organisms
Published in Bioinformatics (01-01-2018)“…Abstract Motivation Genetic diversity of non-model organisms offers a repertoire of unique phenotypic features for exploration and cultivation for synthetic…”
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Elementary mode analysis: a useful metabolic pathway analysis tool for characterizing cellular metabolism
Published in Applied microbiology and biotechnology (01-01-2009)“…Elementary mode analysis is a useful metabolic pathway analysis tool to identify the structure of a metabolic network that links the cellular phenotype to the…”
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Computational design and analysis of modular cells for large libraries of exchangeable product synthesis modules
Published in Metabolic engineering (01-09-2021)“…Microbial metabolism can be harnessed to produce a large library of useful chemicals from renewable resources such as plant biomass. However, it is laborious…”
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10
Metabolic Engineering of Escherichia coli for Efficient Conversion of Glycerol to Ethanol
Published in Applied and Environmental Microbiology (01-11-2009)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Engineering a Synthetic Escherichia coli Coculture for Compartmentalized de novo Biosynthesis of Isobutyl Butyrate from Mixed Sugars
Published in ACS synthetic biology (19-01-2024)“…Short-chain esters are versatile chemicals that can be used as flavors, fragrances, solvents, and fuels. The de novo ester biosynthesis consists of diverging…”
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Endogenous carbohydrate esterases of Clostridium thermocellum are identified and disrupted for enhanced isobutyl acetate production from cellulose
Published in Biotechnology and bioengineering (01-07-2020)“…Medium‐chain esters are versatile chemicals with broad applications as flavors, fragrances, solvents, and potential drop‐in biofuels. Currently, these esters…”
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13
Minimal Escherichia coli Cell for the Most Efficient Production of Ethanol from Hexoses and Pentoses
Published in Applied and Environmental Microbiology (01-06-2008)“…To obtain an efficient ethanologenic Escherichia coli strain, we reduced the functional space of the central metabolic network, with eight gene knockout…”
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14
Controlling selectivity of modular microbial biosynthesis of butyryl-CoA-derived designer esters
Published in Metabolic engineering (01-01-2022)“…Short-chain esters have broad utility as flavors, fragrances, solvents, and biofuels. Controlling selectivity of ester microbial biosynthesis has been an…”
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Elucidating and reprogramming Escherichia coli metabolisms for obligate anaerobic n-butanol and isobutanol production
Published in Applied microbiology and biotechnology (01-08-2012)“…Elementary mode (EM) analysis based on the constraint-based metabolic network modeling was applied to elucidate and compare complex fermentative metabolisms of…”
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Understanding and Eliminating the Detrimental Effect of Thiamine Deficiency on the Oleaginous Yeast Yarrowia lipolytica
Published in Applied and environmental microbiology (21-01-2020)“…Thiamine is a vitamin that functions as a cofactor for key enzymes in carbon and energy metabolism in all living cells. While most plants, fungi, and bacteria…”
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Expanding the modular ester fermentative pathways for combinatorial biosynthesis of esters from volatile organic acids
Published in Biotechnology and bioengineering (01-08-2016)“…ABSTRACT Volatile organic acids are byproducts of fermentative metabolism, for example, anaerobic digestion of lignocellulosic biomass or organic wastes, and…”
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Rewiring metabolism of Clostridium thermocellum for consolidated bioprocessing of lignocellulosic biomass poplar to produce short-chain esters
Published in Bioresource technology (01-09-2023)“…[Display omitted] •Engineered C. thermocellum compatible with CBP for ester production from poplar.•Discovered minor thioesterase activities of esterases…”
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Engineering modular ester fermentative pathways in Escherichia coli
Published in Metabolic engineering (01-11-2014)“…Sensation profiles are observed all around us and are made up of many different molecules, such as esters. These profiles can be mimicked in everyday items for…”
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CRISPR/Cas9-mediated targeted mutagenesis for functional genomics research of crassulacean acid metabolism plants
Published in Journal of experimental botany (29-11-2019)“…Abstract Crassulacean acid metabolism (CAM) is an important photosynthetic pathway in diverse lineages of plants featuring high water-use efficiency and…”
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