Search Results - "Trindade, Rogério Valim"
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2‑(Quinolin-4-yloxy)acetamides Are Active against Drug-Susceptible and Drug-Resistant Mycobacterium tuberculosis Strains
Published in ACS medicinal chemistry letters (10-03-2016)“…2-(Quinolin-4-yloxy)acetamides have been described as potent in vitro inhibitors of Mycobacterium tuberculosis growth. Herein, additional chemical…”
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2
New insights into the SAR and drug combination synergy of 2-(quinolin-4-yloxy)acetamides against Mycobacterium tuberculosis
Published in European journal of medicinal chemistry (27-01-2017)“…2-(Quinolin-4-yloxy)acetamides have been described as potent and selective in vitro inhibitors of Mycobacterium tuberculosis (Mtb) growth. Herein, a new series…”
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Mefloquine and its oxazolidine derivative compound are active against drug-resistant Mycobacterium tuberculosis strains and in a murine model of tuberculosis infection
Published in International journal of antimicrobial agents (01-08-2016)“…Highlights • Mefloquine and its oxazolidine derivative 1E were active in a murine model of tuberculosis (TB). • Mefloquine and 1E were active after oral…”
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