Search Results - "Trinath, Jamma"

UDCA ameliorates inflammation driven EMT by inducing TGR5 dependent SOCS1 expression in mouse macrophages by Fathima, Ashna, Jamma, Trinath

“…Long-standing chronic inflammation of the digestive tract leads to Inflammatory Bowel Diseases (IBD), comprising Crohn’s Disease (CD) and Ulcerative colitis…”
Get full text

Bile acid metabolites control TH17 and Treg cell differentiation by Hang, Saiyu, Paik, Donggi, Yao, Lina, Kim, Eunha, Trinath, Jamma, Lu, Jingping, Ha, Soyoung, Nelson, Brandon N., Kelly, Samantha P., Wu, Lin, Zheng, Ye, Longman, Randy S., Rastinejad, Fraydoon, Devlin, A. Sloan, Krout, Michael R., Fischbach, Michael A., Littman, Dan R., Huh, Jun R.

“…Bile acids are abundant in the mammalian gut, where they undergo bacteria-mediated transformation to generate a large pool of bioactive molecules. Although…”
Get full text

Endoplasmic Reticulum Stress and Intestinal Inflammation: A Perilous Union by Eugene, Sanchez Preethi, Reddy, Vadde Sudhakar, Trinath, Jamma

“…The intestinal tract encompasses the largest mucosal surface fortified with a fine layer of intestinal epithelial cells along with highly sophisticated network…”
Get full text

Extracellular small heat shock proteins: exosomal biogenesis and function by Reddy, V. Sudhakar, Madala, Satish K., Trinath, Jamma, Reddy, G. Bhanuprakash

“…Small heat shock proteins (sHsps) belong to the family of heat shock proteins (Hsps): some are induced in response to multiple stressful events to protect the…”
Get full text

Current trends with FOXP3 + regulatory T cell immunotherapy to contest autoimmunity and inflammation by Trinath, Jamma, Bayry, Jagadeesh

“…While Phase I clinical trial with adult T1D patients provided a proof of concept for the safer utilization of Tregs as adoptive immunotherapy, a further study…”
Get full text

Implication of homocysteine in protein quality control processes by Reddy, V. Sudhakar, Trinath, Jamma, Reddy, G. Bhanuprakash

“…Homocysteine (Hcy) is a key metabolite generated during methionine metabolism. The elevated levels of Hcy in the blood are reffered to as hyperhomocystenimeia…”
Get full text

The WNT Signaling Pathway Contributes to Dectin-1-Dependent Inhibition of Toll-Like Receptor-Induced Inflammatory Signature by Trinath, Jamma, Holla, Sahana, Mahadik, Kasturi, Prakhar, Praveen, Singh, Vikas, Balaji, Kithiganahalli Narayanaswamy

“…Macrophages regulate cell fate decisions during microbial challenges by carefully titrating signaling events activated by innate receptors such as dectin-1 or…”
Get full text

Host-gut microbiota derived secondary metabolite mediated regulation of Wnt/β-catenin pathway: a potential therapeutic axis in IBD and CRC by Kumar, Sushma S, Fathima, Ashna, Srihari, Preeti, Jamma, Trinath

“…The intestinal tract encompasses one of the largest mucosal surfaces with a well-structured layer of intestinal epithelial cells supported by a network of…”
Get full text

Design, Synthesis, and Biological Evaluation of Novel Quinazolin-4(3H)-One-Based Histone Deacetylase 6 (HDAC6) Inhibitors for Anticancer Activity by Khetmalis, Yogesh Mahadu, Fathima, Ashna, Schweipert, Markus, Debarnot, Cécile, Bandaru, Naga Venkata Madhusudhan Rao, Murugesan, Sankaranarayanan, Jamma, Trinath, Meyer-Almes, Franz-Josef, Sekhar, Kondapalli Venkata Gowri Chandra

“…A series of novel quinazoline-4-(3H)-one derivatives were designed and synthesized as histone deacetylase 6 (HDAC6) inhibitors based on novel…”
Get full text

Withametelin inhibits TGF-β induced Epithelial-to-Mesenchymal Transition and Programmed-Death Ligand-1 expression in vitro by Fathima, Ashna, Farboodniay Jahromi, Mohammad Ali, Begum, Sajeli A, Jamma, Trinath

“…Withanolides are a group of naturally occurring plant-based small molecules known for their wide range of host cellular functions. The anticancer potential of…”
Get full text

Targeting hexokinase 2 for oral cancer therapy: structure-based design and validation of lead compounds by Chakraborty, Purbali, Lubna, Syeda, Bhuin, Shouvik, K, Deepika, Chakravarty, Manab, Jamma, Trinath, Yogeeswari, Perumal

“…The pursuit of small molecule inhibitors targeting hexokinase 2 (HK2) has significantly captivated the field of cancer drug discovery. Nevertheless, the…”
Get full text

Regulatory T cell frequency, but not plasma IL-33 levels, represents potential immunological biomarker to predict clinical response to intravenous immunoglobulin therapy by Maddur, Mohan S, Stephen-Victor, Emmanuel, Das, Mrinmoy, Prakhar, Praveen, Sharma, Varun K, Singh, Vikas, Rabin, Magalie, Trinath, Jamma, Balaji, Kithiganahalli N, Bolgert, Francis, Vallat, Jean-Michel, Magy, Laurent, Kaveri, Srini V, Bayry, Jagadeesh

“…Intravenous immunoglobulin (IVIG) is a polyspecific pooled immunoglobulin G preparation and one of the commonly used therapeutics for autoimmune diseases…”
Get full text

Author Correction: Bile acid metabolites control TH17 and Treg cell differentiation by Hang, Saiyu, Paik, Donggi, Yao, Lina, Kim, Eunha, Trinath, Jamma, Lu, Jingping, Ha, Soyoung, Nelson, Brandon N., Kelly, Samantha P., Wu, Lin, Zheng, Ye, Longman, Randy S., Rastinejad, Fraydoon, Devlin, A. Sloan, Krout, Michael R., Fischbach, Michael A., Littman, Dan R., Huh, Jun R.

“…An Amendment to this paper has been published and can be accessed via a link at the top of the paper…”
Get full text

Intravenous immunoglobulin-mediated expansion of regulatory T cells in autoimmune patients is associated with increased prostaglandin E2 levels in the circulation by Maddur, Mohan S, Trinath, Jamma, Rabin, Magalie, Bolgert, Francis, Guy, Moneger, Vallat, Jean-Michel, Magy, Laurent, Balaji, Kithiganahalli N, Kaveri, Srini V, Bayry, Jagadeesh

“…CD4＋FoxP3＋ regulatory T cells （Tregs） are immunosuppressive cells that are critical for immune tolerance. Several studies have demonstrated that one of the…”
Get full text

SALL4 Expression in Epithelial Gastric Cancer: Epigenetic or Epiphenomenon? by Jamma, Trinath

Get full text

Intravenous immunoglobulin-mediated regulation of Notch ligands on human dendritic cells by Trinath, Jamma, MSc, Hegde, Pushpa, MSc, Balaji, Kithiganahalli N., PhD, Kaveri, Srini V., DVM, PhD, Bayry, Jagadeesh, DVM, PhD

“…Furthermore, DCs show enormous diversity and various subsets of DCs have been identified on the basis of tissue distribution, expression of innate receptors,…”
Get full text

Functional Analysis of DNMT1 SNPs (rs2228611 and rs2114724) Associated with Schizophrenia by Saxena, Sonal, Maroju, Pranay Amruth, Choudhury, Sumana, Voina, Vidhya Chitta, Naik, Poonam, Gowdhaman, Kavitha, Kkani, Poornima, Chennoju, Kiranmai, Ganesh Kumar, S., Ramasubramanian, C., Prasad Rao, G., Jamma, Trinath, Narayan, Kumar Pranav, Mohan, K. Naga

“…A recent study showed the association of minor alleles of rs2228611 (T allele) and rs2114724 (T allele) of DNMT1 with schizophrenia (SZ) and suggested their…”
Get full text

Combining structure-based and 3D QSAR pharmacophore models to discover diverse ligands against EGFR in oral cancer by Chakraborty, Purbali, Ahil, Sajeli Begum, Jamma, Trinath, Yogeeswari, Perumal

“…Epidermal growth factor receptor-tyrosine kinase (EGFR-TK) is a well-known hallmark of oral and oropharyngeal cancers, as its overexpression leads to poor…”
Get full text

Intravenous immunoglobulin expands regulatory T cells via induction of cyclooxygenase-2–dependent prostaglandin E2 in human dendritic cells by Trinath, Jamma, Hegde, Pushpa, Sharma, Meenu, Maddur, Mohan S., Rabin, Magalie, Vallat, Jean-Michel, Magy, Laurent, Balaji, Kithiganahalli N., Kaveri, Srini V., Bayry, Jagadeesh

“…CD4+CD25+FoxP3+ regulatory T cells (Tregs) play a critical role in the maintenance of immune tolerance. Intravenous immunoglobulin (IVIg), a therapeutic…”
Get full text

Author Correction: Bile acid metabolites control T.sub.H17 and T.sub.reg cell differentiation by Hang, Saiyu, Paik, Donggi, Yao, Lina, Kim, Eunha, Trinath, Jamma, Lu, Jingping, Ha, Soyoung

“…An Amendment to this paper has been published and can be accessed via a link at the top of the paper…”
Get full text