Search Results - "Trim, Logan K."
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Chlamydia pneumoniae can infect the central nervous system via the olfactory and trigeminal nerves and contributes to Alzheimer’s disease risk
Published in Scientific reports (17-02-2022)“…Chlamydia pneumoniae is a respiratory tract pathogen but can also infect the central nervous system (CNS). Recently, the link between C. pneumoniae CNS…”
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Chlamydia muridarum Can Invade the Central Nervous System via the Olfactory and Trigeminal Nerves and Infect Peripheral Nerve Glial Cells
Published in Frontiers in cellular and infection microbiology (08-01-2021)“…can infect the brain and has been linked to late-onset dementia. , which infects mice, is often used to model human chlamydial infections. While it has been…”
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A novel murine model mimicking male genital Neisseria species infection using Neisseria musculi
Published in Biology of reproduction (08-07-2024)“…With ∼78 million cases yearly, the sexually transmitted bacterium Neisseria gonorrhoeae is an urgent threat to global public health due to continued emergence…”
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Detection of chlamydia infection within human testicular biopsies
Published in Human reproduction (Oxford) (02-10-2019)“…Abstract STUDY QUESTION Can Chlamydia be found in the testes of infertile men? SUMMARY ANSWER Chlamydia can be found in 16.7% of fresh testicular biopsies and…”
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Pathogenic NKT cells attenuate urogenital chlamydial clearance and enhance infertility
Published in Scandinavian journal of immunology (01-05-2023)“…Urogenital chlamydial infections continue to increase with over 127 million people affected annually, causing significant economic and public health pressures…”
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Prophylactic and therapeutic vaccination protects sperm health from Chlamydia muridarum-induced abnormalities
Published in Biology of reproduction (10-05-2023)“…Chlamydia is the most common bacterial sexually transmitted infection worldwide and it is widely acknowledged that controlling the rampant community…”
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Controlled release vaccine implants for delivery of booster immunisations
Published in Veterinary immunology and immunopathology (01-11-2022)Get full text
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Viral-vectored boosting of OmcB- or CPAF-specific T-cell responses fail to enhance protection from Chlamydia muridarum in infection-immune mice and elicits a non-protective CD8-dominant response in naïve mice
Published in Mucosal immunology (01-10-2024)“…A vaccine is needed to combat the Chlamydia epidemic. Replication-deficient viral vectors are safe and induce antigen-specific T-cell memory. We tested the…”
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Hematogenous dissemination of Chlamydia muridarum from the urethra in macrophages causes testicular infection and sperm DNA damage
Published in Biology of reproduction (25-10-2019)“…The incidence of Chlamydia infection, in both females and males, is increasing worldwide. Male infections have been associated clinically with urethritis,…”
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IgG exacerbates genital chlamydial pathology in females by enhancing pathogenic CD8+ T cell responses
Published in Scandinavian journal of immunology (01-01-2024)“…Chlamydia trachomatis infections are an important sexually transmitted infection that can lead to inflammation, scarring and hydrosalpinx/infertility. However,…”
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Primary oral vaccination followed by a vaginal pull protects mice against genital HSV‐2 infection
Published in American journal of reproductive immunology (1989) (01-03-2023)“…Problem HSV‐2 infected more than 491 million people aged 15–49 world‐wide in 2016. The morbidity associated with recurrent infections and the increased risk of…”
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Chronic testicular Chlamydia muridarum infection impairs mouse fertility and offspring development
Published in Biology of reproduction (15-04-2020)“…With approximately 131 million new genital tract infections occurring each year, Chlamydia is the most common sexually transmitted bacterial pathogen…”
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DNA damage contributes to transcriptional and immunological dysregulation of testicular cells during Chlamydia infection
Published in American journal of reproductive immunology (1989) (01-07-2021)“…Chlamydia is the most commonly reported sexually transmitted bacterial infection, with 127 million notifications worldwide each year. Both males and females…”
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