Search Results - "Trill, John"

A G Protein-coupled Receptor for UDP-glucose by Chambers, Jon K., Macdonald, Lynn E., Sarau, Henry M., Ames, Robert S., Freeman, Katie, Foley, James J., Zhu, Yuan, McLaughlin, Megan M., Murdock, Paul, McMillan, Lynette, Trill, John, Swift, Ann, Aiyar, Nambi, Taylor, Paul, Vawter, Lisa, Naheed, Sajda, Szekeres, Philip, Hervieu, Guillaume, Scott, Claire, Watson, Jeanette M., Murphy, Andrew J., Duzic, Emir, Klein, Christine, Bergsma, Derk J., Wilson, Shelagh, Livi, George P.

“…Uridine 5′-diphosphoglucose (UDP-glucose) has a well established biochemical role as a glycosyl donor in the enzymatic biosynthesis of carbohydrates. It is…”
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Discovery of potent, selective sulfonylfuran urea endothelial lipase inhibitors by Goodman, Krista B., Bury, Michael J., Cheung, Mui, Cichy-Knight, Maria A., Dowdell, Sarah E., Dunn, Allison K., Lee, Dennis, Lieby, Jeffrey A., Moore, Michael L., Scherzer, Daryl A., Sha, Deyou, Suarez, Dominic P., Murphy, Dennis J., Harpel, Mark R., Manas, Eric S., McNulty, Dean E., Annan, Roland S., Matico, Rosalie E., Schwartz, Benjamin K., Trill, John J., Sweitzer, Thomas D., Wang, Da-yuan, Keller, Paul M., Krawiec, John A., Jaye, Michael C.

“…A series of potent, selective sulfonylfuran urea endothelial lipase inhibitors is reported. Mechanism of action studies are also discussed. Endothelial lipase…”
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A high-throughput screen for endothelial lipase using HDL as substrate by Keller, Paul M, Rust, Timothy, Murphy, Dennis J, Matico, Rosalie, Trill, John J, Krawiec, John A, Jurewicz, Anthony, Jaye, Michael, Harpel, Mark, Thrall, Sara, Schwartz, Benjamin

“…Endothelial lipase (EL) is a 482-amino-acid protein from the triglyceride lipase gene family that uses a Ser-His-Asp triad for catalysis. Its expression in…”
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Production of monoclonal antibodies in COS and CHO cells by Trill, John J, Shatzman, Allan R, Subinay, Ganguly

“…Recent advances in the generation of genetically engineered monoclonal antibodies have enhanced the importance of COS cells as expression systems for rapidly…”
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Selective Binding and Oligomerization of the Murine Granulocyte Colony-stimulating Factor Receptor by a Low Molecular Weight, Nonpeptidyl Ligand by Doyle, Michael L, Tian, Shin-Shay, Miller, Stephen G, Kessler, Linda, Baker, Audrey E, Brigham-Burke, Michael R, Dillon, Susan B, Duffy, Kevin J, Keenan, Richard M, Lehr, Ruth, Rosen, Jon, Schneeweis, Lumelle A, Trill, John, Young, Peter R, Luengo, Juan I, Lamb, Peter

“…Granulocyte colony-stimulating factor regulates neutrophil production by binding to a specific receptor, the granulocyte colony-stimulating factor receptor,…”
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Rapid expression of recombinant proteins in modified CHO cells using the baculovirus system by RAMOS, Luciano, KOPEC, Lisa A, SWEITZER, Sharon M, FORNWALD, James A, HUIZHEN ZHAO, MCALLISTER, Paul, MCNULTY, Dean E, TRILL, John J, KANE, James F

“…Baculovirus containing the mammalianCMV promoter, in place of the insect polyhedronpromoter (BacMam), has been used to transientlytransfect COS, CHO and CHOE1a…”
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A bicistronic expression system for bacterial production of authentic human interleukin-18 by Kirkpatrick, Robert B, McDevitt, Patrick J, Matico, Rosalie E, Nwagwu, Silas, Trulli, Stephen H, Mao, Joyce, Moore, Dwight D, Yorke, Adam F, McLaughlin, Megan M, Knecht, Kristin A, Elefante, Louis C, Calamari, Amy S, Fornwald, Jim A, Trill, John J, Jonak, Zdenka L, Kane, James, Patel, Pramathesh S, Sathe, Ganesh M, Shatzman, Allan R, Tapley, Peter M, Johanson, Kyung O

“…Interleukin-18 (IL-18) is activated and released from immune effector cells to stimulate acquired and innate immune responses involving T and natural killer…”
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Identification and Cloning of a Connective Tissue Growth Factor-like cDNA from Human Osteoblasts Encoding a Novel Regulator of Osteoblast Functions by Kumar, S, Hand, A T, Connor, J R, Dodds, R A, Ryan, P J, Trill, J J, Fisher, S M, Nuttall, M E, Lipshutz, D B, Zou, C, Hwang, S M, Votta, B J, James, I E, Rieman, D J, Gowen, M, Lee, J C

“…We have identified and cloned a novel connective tissue growth factor-like (CTGF-L) cDNA from primary human osteoblast cells encoding a 250-amino acid single…”
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erratum: Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14 by Ames, Robert S, Sarau, Henry M, Chambers, Johathan K, Willette, Robert N, Aiyar, Nambi V, Romanic, Anne M, Louden, Calvert S, Foley, James J, Sauermelch, Charles F, Coatney, Robert W, Ao, Zhaohui, Disa, Jyoti, Holmes, Stephen D, Stadel, Jeffrey M, Martin, John D, Liu, Wu-Schyong, Glover, George I, Wilson, Shelagh, McNulty, Dean E, Ellis, Catherine E, Elshourbagy, Nabil A, Shabon, Usman, Trill, John J, Hay, Douglas W. P, Ohlstein, Eliot H, Bergsma, Derk J, Douglas, Stephen A

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Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14 by Ames, Robert S, Sarau, Henry M, Chambers, Johathan K, Willette, Robert N, Aiyar, Nambi V, Romanic, Anne M, Louden, Calvert S, Foley, James J, Sauermelch, Charles F, Coatney, Robert W, Ao, Zhaohui, Disa, Jyoti, Holmes, Stephen D, Stadel, Jeffrey M, Martin, John D, Liu, Wu-Schyong, Glover, George I, Wilson, Shelagh, McNulty, Dean E, Ellis, Catherine E, Elshourbagy, Nabil A, Shabon, Usman, Trill, John J, Hay, Douglas W. P, Ohlstein, Eliot H, Bergsma, Derk J, Douglas, Stephen A

“…Urotensin-II (U-II) is a vasoactive 'somatostatin-like' cyclic peptide which was originally isolated from fish spinal cords, and which has recently been cloned…”
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Characterization of pristane‐induced arthritis, a murine model of chronic disease: Response to antirheumatic agents, expression of joint cytokines, and immunopathology by Patten, Christopher, Bush, Katherine, Rioja, Inma, Morgan, Rebecca, Wooley, Paul, Trill, John, Life, Paul

“…Objective To characterize chronic murine pristane‐induced arthritis (PIA) with regard to the response to antirheumatic agents, expression levels of…”
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Purification and Reconstitution of Recombinant Myostatin Latent Complex by Zhang, Hong, Trill, John, Johnson, Kathleen, Scott, Gilbert, Kull, Frederick, Johanson, Kyung

“…Abstract only Myostatin (GDF‐8) is a member of the TGF b super family. It is expressed in skeletal muscle and acts as a negative regulator of skeletal muscle…”
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Characterization of the Glycosylation Profiles of Alzheimer's β-Secretase Protein Asp-2 Expressed in a Variety of Cell Lines by Charlwood, Joanne, Dingwall, Colin, Matico, Rosalie, Hussain, Ishrut, Johanson, Kyung, Moore, Stephen, Powell, David J., Skehel, J. Mark, Ratcliffe, Steve, Clarke, Brian, Trill, John, Sweitzer, Sharon, Camilleri, Patrick

“…Amyloid 39–42 β -peptides are the main components of amyloid plaques found in the brain of Alzheimer's disease patients. Amyloid 39–42 β-peptide is formed from…”
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BacMam recombinant baculoviruses in G protein-coupled receptor drug discovery by Ames, Robert, Fornwald, James, Nuthulaganti, Parvathi, Trill, John, Foley, James, Buckley, Peter, Kost, Thomas, Wu, Zining, Romanos, Michael

“…With completion of the sequencing of the human and mouse genomes, the primary sequences of close to 400 non-olfactory G protein-coupled receptors (GPCRs) have…”
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Characterization of the Glycosylation Profiles of Alzheimer's β-Secretase Protein Asp-2 Expressed in a Variety of Cell Lines by Joanne Charlwood, Colin Dingwall, Rosalie Matico, Ishrut Hussain, Kyung Johanson, Stephen Moore, David J. Powell, J. Mark Skehel, Steve Ratcliffe, Brian Clarke, John Trill, Sharon Sweitzer, Patrick Camilleri

“…Amyloid 39–42 β -peptides are the main components of amyloid plaques found in the brain of Alzheimer's disease patients. Amyloid 39–42 β-peptide is…”
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Cloning, expression and functional characterization of type 1 and type 2 steroid 5α-reductases from Cynomolgus monkey: Comparisons with human and rat isoenzymes by Levy, Mark A., Brandt, Martin, Sheedy, Kristina M., Holt, Dennis A., Heaslip, Julie I., Trill, John J., Ryan, Paul J., Morris, RenéA., Garrison, Linda M., Bergsma, Derk J.

“…The Cynomolgus monkey may provide an alternative pharmacological model in which to evaluate the efficacy of novel inhibitors of the two known human steroid…”
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Human AT1 receptor is a single copy gene : characterization in a stable cell line by NAMBI AIYAR, BAKER, E, HSIAO-LING WU, PONNAL NAMBI, EDWARDS, R. M, TRILL, J. J, ELLIS, C, BERGSMA, D. J

“…To address conflicting reports concerning the number of angiotensin II (AII) receptor type 1 (AT1) coding loci in vertebrates, Southern blot analysis was used…”
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The soluble form of E-selectin is an asymmetric monomer. Expression, purification, and characterization of the recombinant protein by Hensley, P, McDevitt, P J, Brooks, I, Trill, J J, Feild, J A, McNulty, D E, Connor, J R, Griswold, D E, Kumar, N V, Kopple, K D

“…The gene coding for a soluble form of human E-selectin (sE-selectin) has been expressed in Chinese hamster ovary (CHO) cells. Cells seeded into a hollow fiber…”
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The Gene for the Human Immune Interferon Receptor is Located on Chromosome 6 by Rashidbaigi, Abbas, Langer, Jerome A., Jung, Vincent, Jones, Carol, Morse, Helvise G., Tischfield, Jay A., Trill, John J., Kung, Hsiang-Fu, Pestka, Sidney

“…When 32P-labeled human recombinant immune interferon γ (Hu-[32P]IFN-γ is crosslinked to human cells with disuccinimidyl suberate, a complex with a molecular…”
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Use of two different deoxyribonucleic acid probes to detect Y chromosome deoxyribonucleic acid in subjects with normal and altered Y chromosomes by McDonough, P G, Tho, S P, Trill, J J, Byrd, J R, Reindollar, R H, Tischfield, J A

“…Four experiments evaluated the sensitivity and specificity of molecular techniques to detect human Y chromosome deoxyribonucleic acid. In experiment I,…”
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