Search Results - "Trigo‐Mouriño, Pablo"

Rapid antibody conformational screening by matrix‐assisted laser desorption/ionization hydrogen‐deuterium exchange mass spectrometry by Mukherjee, Debopreeti, Trigo‐Mouriño, Pablo, Jiang, Yuan, Nowak, Timothy, Shchurik, Vladimir, Adpressa, Donovon A., Louie, Michael T., Reynolds, Shane R., Hohn, Michael J., Al‐Sayah, Mohammad Ahmed, Pirrone, Gregory F., Makarov, Alexey A.

“…Recent advances in the field of cancer biology have accelerated the discovery and development of novel biopharmaceuticals. At the forefront of these drug…”
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Structural Discrimination in Small Molecules by Accurate Measurement of Long-Range Proton-Carbon NMR Residual Dipolar Couplings by Trigo-Mouriño, Pablo, Navarro-Vázquez, Armando, Ying, Jinfa, Gil, Roberto R., Bax, Ad

“…Accurate measurement of long‐range CH residual dipolar couplings (RDCs; 2DCH and 3DCH) by a new selective J‐scaled HSQC experiment significantly improves the…”
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Probing Spatial Distribution of Alignment by Deuterium NMR Imaging by Trigo-Mouriño, Pablo, Merle, Christian, Koos, Martin R. M., Luy, Burkhard, Gil, Roberto R.

“…Deuterium NMR imaging was used to evaluate the spatial distribution of the degree of alignment in different types of alignment media by monitoring the…”
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Self-Sensitized Photooxygenation of 2H‑Pyrans: Characterization of Unexpected Products Assisted by Computed Structural Elucidation and Residual Dipolar Couplings by Riveira, Martín J, Trigo-Mouriño, Pablo, Troche-Pesqueira, Eduardo, Martin, Gary E, Navarro-Vázquez, Armando, Mischne, Mirta P, Gil, Roberto R

“…The UVA (350 nm) irradiation of an α-pyran in the presence of oxygen led to the unexpected formation of a tetraoxygenated compound whose structure could not be…”
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Conformational Analysis of the Anti-obesity Drug Lorcaserin in Water: How To Take Advantage of Long-Range Residual Dipolar Couplings by Trigo-Mouriño, Pablo, de la Fuente, M. Carmen, Gil, Roberto R., Sánchez-Pedregal, Víctor M., Navarro-Vázquez, Armando

“…The conformational state of 8‐chloro‐1‐methyl‐2,3,4,5‐tetrahydro‐1H‐3‐benzazepine hydrochloride (lorcaserin) in water has been determined on the basis of…”
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Conformational Analysis of an Isoquinolinium Hydrochloride in Water Using Residual Dipolar Couplings by Trigo-Mouriño, Pablo, Santamaría-Fernández, Raquel, Sánchez-Pedregal, Víctor M, Navarro-Vázquez, Armando

“…The use of the cetylpyridinium chloride (CPCL)/NaCl/hexanol liquid crystal allowed the measurement of 1 D CH residual dipolar couplings of the isoquinoline…”
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Influence of solvent and salt concentration on the alignment properties of acrylamide copolymer gels for the measurement of RDC by Trigo-Mouriño, Pablo, Navarro-Vázquez, Armando, Sánchez-Pedregal, Víctor M.

“…The dependence of molecular alignment with solvent nature and salt concentration has been investigated for mechanically stretched polyacrylamide copolymer…”
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Label-free NMR-based dissociation kinetics determination by Trigo-Mouriño, Pablo, Griesinger, Christian, Lee, Donghan

“…Understanding the dissociation of molecules is the basis to modulate interactions of biomedical interest. Optimizing drugs for dissociation rates is found to…”
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Total Synthesis of Darobactin A by Nesic, Marko, Ryffel, David B., Maturano, Jonathan, Shevlin, Michael, Pollack, Scott R., Gauthier, Donald R., Trigo-Mouriño, Pablo, Zhang, Li-Kang, Schultz, Danielle M., McCabe Dunn, Jamie M., Campeau, Louis-Charles, Patel, Niki R., Petrone, David A., Sarlah, David

“…The collaborative total synthesis of darobactin A, a recently isolated antibiotic that selectively targets Gram-negative bacteria, has been accomplished in a…”
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Solution structure and functional investigation of human guanylate kinase reveals allosteric networking and a crucial role for the enzyme in cancer by Khan, Nazimuddin, Shah, Parag P., Ban, David, Trigo-Mouriño, Pablo, Carneiro, Marta G., DeLeeuw, Lynn, Dean, William L., Trent, John O., Beverly, Levi J., Konrad, Manfred, Lee, Donghan, Sabo, T. Michael

“…Human guanylate kinase (hGMPK) is the only known enzyme responsible for cellular GDP production, making it essential for cellular viability and proliferation…”
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Structural Discrimination in Small Molecules by Accurate Measurement of Long-Range Proton-Carbon NMR Residual Dipolar Couplings by Trigo-Mouriño, Pablo, Navarro-Vázquez, Armando, Ying, Jinfa, Gil, Roberto R., Bax, Ad

“…Die genaue Bestimmung von dipolaren CH‐Restkopplungen (RDCs; 2DCH und 3DCH) in einem selektiven J‐skalierten HSQC‐Experiment verbessert die Möglichkeiten der…”
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Label-free NMR-based dissociation kinetics determination by Trigo-Mouriño, Pablo, Griesinger, Christian, Lee, Donghan

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Sampling of Glycan-Bound Conformers by the Anti-HIV Lectin Oscillatoria agardhii agglutinin in the Absence of Sugar by Carneiro, Marta G., Koharudin, Leonardus M. I., Ban, David, Sabo, T. Michael, Trigo-Mourino, Pablo, Mazur, Adam, Griesinger, Christian, Gronenborn, Angela M., Lee, Donghan

“…Lectins from different sources have been shown to interfere with HIV infection by binding to the sugars of viral‐envelope glycoproteins. Three‐dimensional…”
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Determination of the absolute configuration of 19-OH-(-)-eburnamonine using a combination of residual dipolar couplings, DFT chemical shift predictions, and chiroptics by Trigo-Mouriño, Pablo, Sifuentes, Roxana, Navarro-Vázquez, Armando, Gayathri, Chakicherla, Maruenda, Helena, Gil, Roberto R

“…19-OH-(-)-eburnamonine 1 is a new indole alkaloid isolated from Bonafusia macrocalyx. A natural derivative from (-)-eburnamonine for which absolute…”
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Dynamic tuning of FRET in a green fluorescent protein biosensor by Trigo-Mourino, Pablo, Thestrup, Thomas, Griesbeck, Oliver, Griesinger, Christian, Becker, Stefan

“…Förster resonance energy transfer (FRET) between mutants of green fluorescent protein is widely used to monitor protein-protein interactions and as a readout…”
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Self-Sensitized Photooxygenation of 2 H -Pyrans: Characterization of Unexpected Products Assisted by Computed Structural Elucidation and Residual Dipolar Couplings by Riveira, Martín J., Trigo-Mouriño, Pablo, Troche-Pesqueira, Eduardo, Martin, Gary E., Navarro-Vázquez, Armando, Mischne, Mirta P., Gil, Roberto R.

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Sampling of Glycan-Bound Conformers by the Anti-HIV Lectin Oscillatoria agardhii agglutinin in the Absence of Sugar by Carneiro, Marta G., Koharudin, Leonardus M. I., Ban, David, Sabo, T. Michael, Trigo-Mourino, Pablo, Mazur, Adam, Griesinger, Christian, Gronenborn, Angela M., Lee, Donghan

“…Lectins from different sources have been shown to interfere with HIV infection by binding to the sugars of viral‐envelope glycoproteins. Three‐dimensional…”
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Structural Discrimination in Small Molecules by Accurate Measurement of Long-Range Proton-Carbon Residual Dipolar Couplings by Trigo-Mouriño, Pablo, Navarro-Vázquez, Armando, Ying, Jinfa, Gil, Roberto R., Bax, Ad

“…Accurate measurement of long-range CH residual dipolar couplings (RDCs) ( 2 D CH and 3 D CH ) by a new selective J -scaled HSQC experiment significantly…”
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Rapid Characterization of Structural and Behavioral Changes of Therapeutic Proteins by Relaxation and Diffusion 1 H-SOFAST NMR Experiments by Xu, Xingjian, Poggetto, Guilherme Dal, McCoy, Mark, Reibarkh, Mikhail, Trigo-Mourino, Pablo

“…Biologic drugs have emerged as a rapidly expanding and important modality, offering promising therapeutic solutions by interacting with previously…”
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Rapid Characterization of Structural and Behavioral Changes of Therapeutic Proteins by Relaxation and Diffusion 1H‑SOFAST NMR Experiments by Xu, Xingjian, Poggetto, Guilherme Dal, McCoy, Mark, Reibarkh, Mikhail, Trigo-Mourino, Pablo

“…Biologic drugs have emerged as a rapidly expanding and important modality, offering promising therapeutic solutions by interacting with previously…”
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