Search Results - "Trigiante, G"

Synchronous "skip" facial metastases from colorectal adenocarcinoma: a case report and review of literature by Picciariello, A, Tomasicchio, G, Lantone, G, Martines, G, Dibra, R, Trigiante, G, d'Amati, A, Piscitelli, D, Altomare, D F

“…Skin metastases from colorectal adenocarcinoma are rare conditions that are metachronous in most of cases and may represent the first sign of a recurrence…”
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The REALISE score: a new statistically validated scoring system to assess the severity of anal fissures by Picciariello, A., Lobascio, P., Spazzafumo, L., Rinaldi, M., Dibra, R., Trigiante, G., Laforgia, R., Pezzolla, A., Altomare, D. F.

“…Background Anal fissure (AF) is a common, painful disease that strongly affects patients’ quality of life, however, no scoring system to assess the severity of…”
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Restorative perineal anorectal amputation for a locally advanced desmoid tumour by Picciariello, Arcangelo, Rinaldi, M., De Fazio, M., Trigiante, G., Papagni, V., Bucaria, V., Altomare, D. F.

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Ageing with sacral nerve modulation for fecal incontinence: how many patients get benefit after more than 10 years? by Picciariello, A., Rinaldi, M., Dibra, R., Trigiante, G., Tomasicchio, G., Lantone, G., De Fazio, M.

“…Sacral nerve modulation (SNM) has represented a major advancement in the minimally invasive management of patients with fecal incontinence (FI). Although the…”
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GLI2 induces genomic instability in human keratinocytes by inhibiting apoptosis by Pantazi, E, Gemenetzidis, E, Trigiante, G, Warnes, G, Shan, L, Mao, X, Ikram, M, Teh, M-T, Lu, Y-J, Philpott, M P

“…Abnormal Sonic Hedgehog signalling leads to increased transcriptional activation of its downstream effector, glioma 2 (GLI2), which is implicated in the…”
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ASPP1 and ASPP2 are new transcriptional targets of E2F by Fogal, V, Kartasheva, N N, Trigiante, G, Llanos, S, Yap, D, Vousden, K H, Lu, X

“…The E2F family of transcription factors regulates the expression of a number of genes whose products are involved in cell cycle control, DNA replication and…”
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612 Targeted hair follicle delivery of hydrophilic molecules by Vootukuri Reddy, S., Philpott, M., Trigiante, G.

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679 Wound Healing properties of OPAL A (patented Carica papaya fruit extract) by Vootukuri, R., Trigiante, G., Philpott, M.

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ASPPs and cancer by Lu, Xin, Trigiante, Giuseppe

“…One of the most frequently mutated genes in human cancers, tumour suppressor p53 (TP53), can induce cell-cycle arrest and apoptosis. The apoptotic function of…”
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A Discrete Approach to the Prime Number Theorem by Trigiante, G., Trigiante, D.

“…An elementary proof of the fundamental theorem on prime numbers is obtained. The result is obtained by defining a new sieve which permits to estimate the…”
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ASPP Proteins Specifically Stimulate the Apoptotic Function of p53 by Samuels-Lev, Yardena, O'Connor, Daniel J., Bergamaschi, Daniele, Trigiante, Giuseppe, Hsieh, Jung-Kuang, Zhong, Shan, Campargue, Isabelle, Naumovski, Louie, Crook, Tim, Lu, Xin

“…We identified a family of proteins termed ASPP. ASPP1 is a protein homologous to 53BP2, the C-terminal half of ASPP2. ASPP proteins interact with p53 and…”
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p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis by Bergamaschi, Daniele, Gasco, Milena, Hiller, Louise, Sullivan, Alexandra, Syed, Nelofer, Trigiante, Giuseppe, Yulug, Isik, Merlano, Marco, Numico, Gianmauro, Comino, Alberto, Attard, Marlene, Reelfs, Olivier, Gusterson, Barry, Bell, Alexandra K, Heath, Victoria, Tavassoli, Mahvash, Farrell, Paul J, Smith, Paul, Lu, Xin, Crook, Tim

“…Intact p73 function is shown to be an important determinant of cellular sensitivity to anticancer agents. Inhibition of p73 function by dominant-negative…”
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(.mu.-Nitrido)((tetraphenylporphyrinato)iron)((phthalocyaninato)iron) and Its Fe-Ru Analog: Redox Behavior and Characterization of New Fe(IV)-Containing Species. X-ray Crystal Structure of [(THF)(TPP)Fe-N-FePc(H2O)](I5).cntdot.2THF by Ercolani, C, Jubb, J, Pennesi, G, Russo, U, Trigiante, G

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Polymorphism in wild-type p53 modulates response to chemotherapy in vitro and in vivo by SULLIVAN, Alexandra, SYED, Nelofer, CROOK, Tim, GASCO, Milena, BERGAMASCHI, Daniele, TRIGIANTE, Giuseppe, ATTARD, Marlene, HILLER, Louise, FARRELL, Paul J, SMITH, Paul, XIN LU

“…A single-nucleotide polymorphism (SNP) in exon 4 results in expression of either arginine (72R) or proline (72P) at codon 72 of p53. We demonstrate that the in…”
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The weekend effect on the provision of Emergency Surgery before and during the COVID-19 pandemic: case-control analysis of a retrospective multicentre database by Tebala, Giovanni D, Milani, Marika S, Cirocchi, Roberto, Bignell, Mark, Bond-Smith, Giles, Lewis, Christopher, Agnoletti, Vanni, Catarci, Marco, Di Saverio, Salomone, Luridiana, Gianluigi, Catena, Fausto, Scatizzi, Marco, Marini, Pierluigi

“…The concept of "weekend effect", that is, substandard healthcare during weekends, has never been fully demonstrated, and the different outcomes of emergency…”
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iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human by Lu, Xin, Bergamaschi, Daniele, Samuels, Yardena, O'Neil, Nigel J, Trigiante, Giuseppe, Crook, Tim, Hsieh, Jung-Kuang, O'Connor, Daniel J, Zhong, Shan, Campargue, Isabelle, Tomlinson, Matthew L, Kuwabara, Patricia E

“…We have previously shown that ASPP1 and ASPP2 are specific activators of p53; one mechanism by which wild-type p53 is tolerated in human breast carcinomas is…”
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The N-terminus of a novel isoform of human iASPP is required for its cytoplasmic localization by SLEE, Elizabeth A, GILLOTIN, Sébastien, BERGAMASCHI, Daniele, ROYER, Christophe, LLANOS, Susana, ALI, Safia, BOQUAN JIN, TRIGIANTE, Giuseppe, XIN LU

“…ASPP1 and ASPP2 are both proteins that interact with p53 and enhance its ability to induce apoptosis by selectively elevating the expression of proapoptotic…”
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Selective virus-mediated intracellular delivery of membrane-impermeant compounds by means of plasma membrane vesicles by Trigiante, Giuseppe, Huestis, Wray H

“…The impermeability of the cell plasma membrane is a major obstacle to intracellular delivery of large hydrophilic molecules, such as many kinds of drugs. This…”
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Pseudo First-Order Cleavage of an Immobilized Substrate by an Enzyme Undergoing Two-Dimensional Surface Diffusion by Trigiante, Giuseppe, Gast, Alice P, Robertson, Channing R

“…In this paper we study the reaction kinetics of an enzyme adsorbed on a peptide substrate surface. Although the adsorption is effectively irreversible, the…”
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Protease Activity on an Immobilized Substrate Modified by Polymers:  Subtilisin BPN by Esker, Alan R, Brode, Philip F, Rubingh, Donn N, Rauch, Deborah S, Yu, Hyuk, Gast, Alice P, Robertson, Channing R, Trigiante, Giuseppe

“…We describe the adsorption and catalytic behavior of the serine protease subtilisin BPN‘ on controlled pore glass (CPG) beads with a short (aminopropyl) or a…”
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