Search Results - "Trifunović Ristovski, Jovana"
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In vitro testing and computational analysis of specific phytochemicals with antiviral activities considering their possible applications against COVID-19
Published in South African journal of botany (01-12-2022)“…The purpose of this study was to investigate the reservoir of natural products against the SARS-CoV-2 virus and to identify suitable candidates in order to…”
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The evaluation of the anticancer activity of the Biginelli hybrids and pharmacokinetic profiling based on their retention parameters
Published in Journal of molecular structure (15-04-2022)“…•Biginelli hybrdis are evaluated against different the cancer cell lines.•Two compounds exhibited higher selectivity and activity compared to…”
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Evaluation of antimicrobial activity and retention behavior of newly synthesized vanilidene derivatives of Meldrum’s acids using QSRR approach
Published in Journal of pharmaceutical and biomedical analysis (05-06-2018)“…•Lipophilicity and antimicrobial activity of 13 vanilidene derivatives of Meldrum’s acid has been evaluated.•Clustering of the compounds according to their…”
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Synthesis, in vitro anticancer activity, and pharmacokinetic profiling of the new tetrahydropyrimidines: Part I
Published in Archiv der Pharmazie (Weinheim) (01-11-2024)“…Different vanillin‐based aldehydes were used to synthesize novel tetrahydropyrimidines (THPMs) via conventional Biginelli reaction. The THPMs were tested…”
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Chitosan nanobeads loaded with Biginelli hybrids as cell-selective toxicity systems with a homogeneous distribution of the cell cycle in cancer treatment
Published in RSC advances (13-11-2020)“…Tetrahydropyrimidines are a class of azaheterocycles, also called Biginelli hybrids (obtained from the Biginelli reaction), that have attracted an enormous…”
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Discovery of the Biginelli hybrids as novel caspase-9 activators in apoptotic machines: Lipophilicity, molecular docking study, influence on angiogenesis gene and miR-21 expression levels
Published in Bioorganic chemistry (01-05-2019)“…[Display omitted] •Cytotoxic properties of novel 1,2,3,4-tetrahydropyrimidines and 1,3,5-oxadiazocines.•4c, 4d, 4f, 4k and 4l showed a good-to-excellent…”
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Minimizing the environmental impact of unused pharmaceuticals: Review focused on prevention
Published in Frontiers in environmental science (16-12-2022)“…Pharmaceuticals are essential for human health, but they become an environmental concern when entering the environment which occurs when residues are excreted…”
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