Search Results - "Trieb, M"
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Anti-inflammatory activity of small-molecule antagonists of Toll-like receptor 2 (TLR2) in mice
Published in Immunobiology (1979) (01-01-2019)“…Toll-like receptor 2 (TLR2) is currently investigated as a potential therapeutic target in diseases with underlying inflammation like sepsis and arthritis. We…”
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Decoy peptides derived from the extracellular domain of toll-like receptor 2 (TLR2) show anti-inflammatory properties
Published in Bioorganic & medicinal chemistry (01-09-2018)“…[Display omitted] Toll-like receptor 2 (TLR2) recognizes bacterial derived- and synthetic-lipopeptides after dimerization with TLR1 or TLR6. Hyper-activation…”
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Liver disease alters high-density lipoprotein composition, metabolism and function
Published in Atherosclerosis (01-09-2016)Get full text
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Cooperative effects on the formation of intercalation sites
Published in Nucleic acids research (01-01-2004)“…Daunomycin is one of the most important agents used in anticancer chemotherapy. It interacts with DNA through intercalation of its planar chromophore between…”
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A1001 - Phospholipase C (PLC) is a crucial mediator of agonist-induced smooth muscle contraction in the lower urinary tract
Published in European urology (01-03-2024)Get full text
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Phospholipase C (PLC) is a crucial mediator of agonist-induced smooth muscle contraction in the lower urinary tract
Published in European urology (01-03-2024)Get full text
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Atrial Fibrillation Is Associated With Alterations In Hdl Function, Metabolism And Particle Number
Published in Atherosclerosis (01-08-2019)Get full text
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P310HDL-function in atrial fibrillation
Published in Cardiovascular research (01-04-2018)Get full text
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Transcriptional profiling of C. elegans DAF-19 uncovers a ciliary base-associated protein and a CDK/CCRK/LF2p-related kinase required for intraflagellar transport
Published in Developmental biology (01-09-2011)“…Cilia are ubiquitous cell surface projections that mediate various sensory- and motility-based processes and are implicated in a growing number of multi-organ…”
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Presynaptic Ca2+-Activated K+ Channels in Glutamatergic Hippocampal Terminals and Their Role in Spike Repolarization and Regulation of Transmitter Release
Published in The Journal of neuroscience (15-12-2001)“…Large-conductance Ca(2+)-activated K(+) channels (BK, also called Maxi-K or Slo channels) are widespread in the vertebrate nervous system, but their functional…”
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Regional Differences in Distribution and Functional Expression of Small-Conductance Ca2+-Activated K+ Channels in Rat Brain
Published in The Journal of neuroscience (15-11-2002)“…Small-conductance Ca2+-activated K+ (SK) channels are important for excitability control and afterhyperpolarizations in vertebrate neurons and have been…”
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Dynamics of DNA: B I and B II Phosphate Backbone Transitions
Published in The journal of physical chemistry. B (19-02-2004)Get full text
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C5-Methylation of Cytosine in B-DNA Thermodynamically and Kinetically Stabilizes BI
Published in Journal of the American Chemical Society (10-12-2003)“…We have examined the backbone dynamics of two alternating purine−pyrimidine dodecamers. One sequence consists of “pure” GC bases; the other one contains…”
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High-Conductance Calcium-Activated Potassium Channels in Rat Brain: Pharmacology, Distribution, and Subunit Composition
Published in Biochemistry (Easton) (27-04-1999)“…In rat brain, high-conductance Ca2+-activated K+ (BK) channels are targeted to axons and nerve terminals [Knaus, H. G., et al. (1996) J. Neurosci. 16,…”
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The N6-Methyl Group of Adenine Further Increases the BI Stability of DNA Compared to C5-Methyl Groups
Published in The journal of physical chemistry. B (13-01-2005)“…Methylated DNA bases are natural modifications which play an important role in protein−DNA interactions. Recent experimental and theoretical results have shown…”
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M.TaqI facilitates the base flipping via an unusual DNA backbone conformation
Published in Biopolymers (15-10-2005)“…MD simulations have been carried out to understand the dynamical behavior of the DNA substrate of the Thermus aquaticus DNA methyltransferase (M.TaqI) in the…”
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Hydration of Hydroxypyrrole Influences Binding of ImHpPyPy-β-Dp Polyamide to DNA
Published in Journal of the American Chemical Society (29-01-2003)“…Ligands which are able to recognize DNA sequence specifically are of fundamental interest as transcription controlling drugs. Recently a polyamide ligand was…”
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