Search Results - "Trick, Jemma"
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Functional Annotation of Ion Channel Structures by Molecular Simulation
Published in Structure (London) (06-12-2016)“…Ion channels play key roles in cell membranes, and recent advances are yielding an increasing number of structures. However, their functional relevance is…”
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Journal Article -
2
Designing a Hydrophobic Barrier within Biomimetic Nanopores
Published in ACS nano (25-11-2014)“…Nanopores in membranes have a range of potential applications. Biomimetic design of nanopores aims to mimic key functions of biological pores within a stable…”
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Journal Article -
3
Voltage Gating of a Biomimetic Nanopore: Electrowetting of a Hydrophobic Barrier
Published in ACS nano (28-02-2017)“…It is desirable that nanopores that are components of biosensors are gated, i.e., capable of controllable switching between closed (impermeable) and open…”
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4
Glycerol Solvates DPPC Headgroups and Localizes in the Interfacial Regions of Model Pulmonary Interfaces Altering Bilayer Structure
Published in Langmuir (12-06-2018)“…The inclusion of glycerol in formulations for pulmonary drug delivery may affect the bioavailability of inhaled steroids by retarding their transport across…”
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Journal Article -
5
Lipid Bilayer Membrane Perturbation by Embedded Nanopores: A Simulation Study
Published in ACS nano (22-03-2016)“…A macromolecular nanopore inserted into a membrane may perturb the dynamic organization of the surrounding lipid bilayer. To better understand the nature of…”
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Journal Article -
6
Molecular simulation studies of hydrophobic gating in nanopores and ion channels
Published in Biochemical Society transactions (01-04-2015)“…Gating in channels and nanopores plays a key role in regulating flow of ions across membranes. Molecular simulations provide a 'computational microscope' which…”
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Journal Article -
7
Electric-Field-Driven Translocation of ssDNA through Hydrophobic Nanopores
Published in ACS nano (28-08-2018)“…The accurate sequencing of DNA using nanopores requires control over the speed of DNA translocation through the pores and also of the DNA conformation. Our…”
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Journal Article -
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The Effects of Cholesterol Oxidation on Erythrocyte Plasma Membranes: A Monolayer Study
Published in Membranes (Basel) (24-08-2022)“…Cholesterol plays a key role in the molecular and mesoscopic organisation of lipid membranes and it is expected that changes in its molecular structure (e.g.,…”
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9
Simulations of Glycerol and its Effect on the Phase and Behaviour of DPPC Monolayers
Published in Biophysical journal (03-02-2017)Get full text
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10
Electric-Field-Driven Translocation of ssDNA through Hydrophobic Nanopores
Published in Biophysical journal (15-02-2019)Get full text
Journal Article -
11
Hydrophobic Gating and Functional Annotation of Ion Channel Structures by Molecular Dynamics Simulations
Published in Biophysical journal (03-02-2017)Get full text
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12
Electro-Wetting of a Hydrophobic Gate in a Biomimetic Nanopore
Published in Biophysical journal (27-01-2015)Get full text
Journal Article -
13
Designing Hydrophobic Gates into Biomimetic Nanopores
Published in Biophysical journal (28-01-2014)Get full text
Journal Article -
14
Simulations and Modelling of Biomimetic Nanopores
Published in Biophysical journal (29-01-2013)Get full text
Journal Article -
15
Computational design of biomimetic nanopores: a molecular dynamics study
Published 01-01-2015“…Molecular dynamics simulations are used to study the function of hydrophobic gates within models of biomimetic nanopores and in ligand-gated ion channels. A…”
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Dissertation -
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Computational design of biomimetic nanopores : a molecular dynamics study
Published 01-01-2015“…Molecular dynamics simulations are used to study the function of hydrophobic gates within models of biomimetic nanopores and in ligand-gated ion channels. A…”
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Dissertation