Estimation of Residual Peritoneal Volume Using Technetium-99m Sulfur Colloid Scintigraphy

Residual peritoneal volume (RPV) may contribute in the development of ultrafiltration failure in patients with normal transcapillary ultrafiltration. The aim of this study was to estimate the RPV using intraperitoneal technetium-99m Sulfur Colloid (Tc). Twenty patients on peritoneal dialysis were st...

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Bibliographic Details
Published in:	ASAIO journal (1992) Vol. 61; no. 4; pp. 459 - 462
Main Authors:	Katopodis, Konstantinos P, Fotopoulos, Andrew D, Balafa, Olga C, Tsiouris, Spyridon Th, Triandou, Eleni G, Al-Bokharhli, Jichad B, Kitsos, Athanasios C, Dounousi, Evagelia C, Siamopoulos, Konstantinos C
Format:	Journal Article
Language:	English
Published:	United States Copyright by the American Society for Artificial Internal Organs 01-07-2015
Subjects:	Colloids Female Humans Male Middle Aged Peritoneal Dialysis - methods Radionuclide Imaging - methods Renal Insufficiency - diagnostic imaging Sulfur Technetium
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Summary:	Residual peritoneal volume (RPV) may contribute in the development of ultrafiltration failure in patients with normal transcapillary ultrafiltration. The aim of this study was to estimate the RPV using intraperitoneal technetium-99m Sulfur Colloid (Tc). Twenty patients on peritoneal dialysis were studied. RPV was estimated by1) intraperitoneal instillation of Tc (RPV-Tc) and 2) classic Twardowski calculations using endogenous solutes, such as urea (RPV-u), creatinine (RPV-cr), and albumin (RPV-alb). Each method’s reproducibility was assessed in a subgroup of patients in two consecutive measurements 48 h apart. Both methods displayed reproducibility (r = 0.93, p = 0.001 for RPVTc and r = 0.90, p = 0.001 for RPV-alb) between days 1 and 2, respectively. We found a statistically significant difference between RPV-Tc and RPV-cr measurements (347.3 ± 116.7 vs. 450.0 ± 67.8 ml; p =0.001) and RPV-u (515.5 ± 49.4 ml; p < 0.001), but not with RPV-alb (400.1 ± 88.2 ml; p = 0.308). A good correlation was observed only between RPV-Tc and RPV-alb (p < 0.001). The Tc method can estimate the RPV as efficiently as the high molecular weight endogenous solute measurement method. It can also provide an imaging estimate of the intraperitoneal distribution of RPV.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1058-2916 1538-943X
DOI:	10.1097/MAT.0000000000000221