Search Results - "Trevor, N"
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QSPRs for Predicting Equilibrium Partitioning in Solvent–Air Systems from the Chemical Structures of Solutes and Solvents
Published in Journal of solution chemistry (01-09-2022)“…Poly-parameter Linear Free Energy Relationships (PPLFERs) based on the Abraham solvation model are a useful tool for predicting and interpreting equilibrium…”
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Ixodidae (Acari: Ixodoidea): descriptions and redescriptions of all known species from 1758 to December 31, 2019
Published in Zootaxa (05-11-2020)“…References to the descriptions and redescriptions of the 742 species of Ixodidae published from 1758 to December 31, 2019 are compiled, with the goal of…”
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Fetal Physiologically Based Pharmacokinetic Models: Systems Information on the Growth and Composition of Fetal Organs
Published in Clinical pharmacokinetics (01-02-2019)“…Background The growth of fetal organs is a dynamic process involving considerable changes in the anatomical and physiological parameters that can alter fetal…”
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Anatomical, Physiological and Metabolic Changes with Gestational Age during Normal Pregnancy: A Database for Parameters Required in Physiologically Based Pharmacokinetic Modelling
Published in Clinical pharmacokinetics (01-06-2012)“…Background: Pregnancy is associated with considerable changes in the physiological, anatomical and biochemical attributes in women. These may alter the…”
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Reaching the 'first 90': Gaps in coverage of HIV testing among people living with HIV in 16 African countries
Published in PloS one (12-10-2017)“…UNAIDS has recently proposed a set of three ambitious targets that, if achieved, are predicted to end the AIDS epidemic by 2030. The targets, known as…”
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A Preterm Physiologically Based Pharmacokinetic Model. Part I: Physiological Parameters and Model Building
Published in Clinical pharmacokinetics (01-04-2020)“…Background Developmental physiology can alter pharmacotherapy in preterm populations. Because of ethical and clinical constraints in studying this vulnerable…”
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Fetal Physiologically Based Pharmacokinetic Models: Systems Information on Fetal Blood Components and Binding Proteins
Published in Clinical pharmacokinetics (01-05-2020)“…Background Fetal blood and plasma volume and binding components are critical parameters in a fetal physiologically based pharmacokinetic model. To date, a…”
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Preterm Physiologically Based Pharmacokinetic Model. Part II: Applications of the Model to Predict Drug Pharmacokinetics in the Preterm Population
Published in Clinical pharmacokinetics (01-04-2020)“…Background Preterm neonates are usually not part of a traditional drug development programme, however they are frequently administered medicines. Developing…”
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Annotation of natural product compound families using molecular networking topology and structural similarity fingerprinting
Published in Nature communications (19-01-2023)“…Spectral matching of MS 2 fragmentation spectra has become a popular method for characterizing natural products libraries but identification remains…”
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Direct Exoplanet Detection using Convolutional Image Reconstruction (ConStruct): A New Algorithm for Post-processing High-contrast Images
Published in The Astronomical journal (01-03-2024)“…We present a novel machine-learning approach for detecting faint point sources in high-contrast adaptive optics (AO) imaging data sets. The most widely used…”
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Vulnerability to watershed erosion and coastal deposition in the tropics
Published in Scientific reports (13-01-2021)“…Over half of the global population is projected to live in the tropics by 2050. Sustainable land development will be challenged by enhanced sediment erosion…”
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Olaparib: A tale of two dosage forms
Published in Seminars in oncology (01-02-2019)“…Olaparib is the first poly(ADP-ribose) polymerase (PARP) inhibitor approved by the Food and Drug Administration (FSA), with three approvals in two different…”
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Prediction of Pediatric Pharmacokinetics for CYP3A4 Metabolized Drugs: Comparison of the Performance of Two Hepatic Ontogeny Within a Physiologically Based Pharmacokinetic Model
Published in Journal of clinical pharmacology (01-09-2024)“…The rapid growth in the use of pediatric physiologically based pharmacokinetic (PBPK) models, particularly for regulatory applications, has focused emphasis on…”
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General Model for Estimating Partition Coefficients to Organisms and Their Tissues Using the Biological Compositions and Polyparameter Linear Free Energy Relationships
Published in Environmental science & technology (18-06-2013)“…Equilibrium partition coefficients of organic chemicals from water to an organism or its tissues are typically estimated by using the total lipid content in…”
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On the Potential for Iatrogenic Effects of Psychiatric Crisis Services: The Example of Dialectical Behavior Therapy for Adult Women With Borderline Personality Disorder
Published in Journal of consulting and clinical psychology (01-02-2018)“…Objective: Although previous research has suggested that people with a history of using psychiatric crisis services are at higher risk for suicide, it is…”
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The zoonotic, fish-borne liver flukes Clonorchis sinensis, Opisthorchis felineus and Opisthorchis viverrini
Published in International journal for parasitology (01-11-2013)“…A generalized life cycle for zoonotic opithorchiid liver flukes. •The three most important liver flukes infect more than 45 million people worldwide.•At least…”
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Fetal Physiologically Based Pharmacokinetic Models: Systems Information on Fetal Cardiac Output and Its Distribution to Different Organs during Development
Published in Clinical pharmacokinetics (01-06-2021)“…Background and Objective Fetal circulation is unique and the parameters describing hemodynamic status during development are critical for constructing a fetal…”
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The ecology of tick-borne diseases
Published in International journal for parasitology (01-11-2013)“…[Display omitted] •The ecology of tick-borne diseases is discussed.•We point out the factors important for tick abundance and distribution.•Abiotic and biotic…”
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A Re-evaluation and Validation of Ontogeny Functions for Cytochrome P450 1A2 and 3A4 Based on In Vivo Data
Published in Clinical pharmacokinetics (01-07-2014)“…Background and Objectives Current cytochrome P450 (CYP) 1A2 and 3A4 ontogeny profiles, which are derived mainly from in vitro studies and incorporated in…”
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The Natural Products Atlas 2.0: a database of microbially-derived natural products
Published in Nucleic acids research (07-01-2022)“…Abstract Within the natural products field there is an increasing emphasis on the study of compounds from microbial sources. This has been fuelled by interest…”
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