Search Results - "Trevisi, Lucia"
-
1
Estrogen, Angiogenesis, Immunity and Cell Metabolism: Solving the Puzzle
Published in International journal of molecular sciences (15-03-2018)“…Estrogen plays an important role in the regulation of cardiovascular physiology and the immune system by inducing direct effects on multiple cell types…”
Get full text
Journal Article -
2
Convenience versus Biological Significance: Are PMA-Differentiated THP-1 Cells a Reliable Substitute for Blood-Derived Macrophages When Studying in Vitro Polarization?
Published in Frontiers in pharmacology (22-02-2018)“…Human peripheral-blood monocytes are used as an established system for generating macrophages. For several reasons, monocytic cell lines such as THP-1 have…”
Get full text
Journal Article -
3
Gender differences and pharmacological regulation of angiogenesis induced by synovial fluids in inflammatory arthritis
Published in Biomedicine & pharmacotherapy (01-08-2022)“…Several mediators including cytokines, growth factors and metalloproteinases (MMP) modulate pathological angiogenesis associated with inflammatory arthritis…”
Get full text
Journal Article -
4
Sex Differences in the Pro-Angiogenic Response of Human Endothelial Cells: Focus on PFKFB3 and FAK Activation
Published in Frontiers in pharmacology (17-12-2020)“…Female hormones and sex-specific factors are established determinants of endothelial function, yet their relative contribution to human endothelium phenotypes…”
Get full text
Journal Article -
5
Sex-dependent PD-L1/sPD-L1 trafficking in human endothelial cells in response to inflammatory cytokines and VEGF
Published in Biomedicine & pharmacotherapy (01-06-2023)“…Programmed cell death 1 ligand 1 (PD-L1) expressed in non-immune cells is involved in immune-mediated tissue damage in the context of inflammatory conditions…”
Get full text
Journal Article -
6
Antiapoptotic effect of ouabain on human umbilical vein endothelial cells
Published in Biochemical and biophysical research communications (27-08-2004)“…The present study investigates the effect of ouabain on caspase-3 activation in human umbilical vein endothelial cells (HUVEC). Ouabain (EC 50 20 nM) reduced…”
Get full text
Journal Article -
7
Isolation of callipeltins A–C and of two new open-chain derivatives of callipeltin A from the marine sponge Latrunculia sp. A revision of the stereostructure of callipeltins
Published in Tetrahedron letters (26-08-2002)“…Two new callipeltin-related acyclic peptides ( 2 and 3 ) have been isolated, together with callipeltins A–C from the marine sponge Latrunculia sp. collected at…”
Get full text
Journal Article -
8
Regulation of human endothelial cell migration by oral contraceptive estrogen receptor ligands
Published in European journal of pharmacology (15-04-2023)“…Ethinylestradiol (EE) and estetrol (E4) are the two main estrogenic agents used in combined oral contraceptives. These compounds have different binding…”
Get full text
Journal Article -
9
Effect of vascular endothelial growth factor and epidermal growth factor on iatrogenic apoptosis in human endothelial cells
Published in Biochemical pharmacology (15-01-2004)“…To study the effect of growth factors on iatrogenic apoptosis, we examined the influence of vascular endothelial growth factor (VEGF) and epidermal growth…”
Get full text
Journal Article -
10
Targeting of PFKFB3 with miR‐206 but not mir‐26b inhibits ovarian cancer cell proliferation and migration involving FAK downregulation
Published in The FASEB journal (01-03-2022)“…Few studies explored the role of microRNAs (miRNAs) in the post‐transcriptional regulation of glycolytic proteins and downstream effectors in ovarian cancer…”
Get full text
Journal Article -
11
The Glycolytic Enzyme PFKFB3 Is Involved in Estrogen-Mediated Angiogenesis via GPER1
Published in The Journal of pharmacology and experimental therapeutics (01-06-2017)“…The endogenous estrogen 17 -estradiol (E2) is a key factor in promoting endothelial healing and angiogenesis. Recently, proangiogenic signals including…”
Get more information
Journal Article -
12
The antiangiogenic effect of digitoxin is dependent on a ROS-elicited RhoA/ROCK pathway activation
Published in Biochemical pharmacology (01-04-2024)“…[Display omitted] We previously showed that digitoxin inhibits angiogenesis and cancer cell proliferation and migration and these effects were associated to…”
Get full text
Journal Article -
13
MiR-206 inhibits estrogen signaling and ovarian cancer cell migration without affecting GPER
Published in Life sciences (1973) (15-11-2023)“…Estrogen-regulated pathways are involved in the etiology and progression of epithelial ovarian cancer (EOC), but the relative contribution of estrogen receptor…”
Get full text
Journal Article -
14
Therapeutic concentrations of digitoxin inhibit endothelial focal adhesion kinase and angiogenesis induced by different growth factors
Published in British journal of pharmacology (01-09-2017)“…Background and Purpose Cardiac glycosides are Na+/K+‐ATPases inhibitors used to treat congestive heart failure and cardiac arrhythmias. Epidemiological studies…”
Get full text
Journal Article -
15
Cardiac glycoside ouabain induces autophagic cell death in non-small cell lung cancer cells via a JNK-dependent decrease of Bcl-2
Published in Biochemical pharmacology (15-05-2014)“…[Display omitted] Cardiac glycosides are Na/K-ATPase inhibitors, clinically used for congestive heart failure and cardiac arrhythmias. Epidemiological studies…”
Get full text
Journal Article -
16
Clinical efficacy and safety of angiogenesis inhibitors: sex differences and current challenges
Published in Cardiovascular research (16-03-2022)“…Abstract Vasoactive molecules, such as vascular endothelial growth factor (VEGF) and endothelins, share cytokine-like activities and regulate endothelial cell…”
Get full text
Journal Article -
17
Non‐genomic mechanisms in the estrogen regulation of glycolytic protein levels in endothelial cells
Published in The FASEB journal (01-09-2020)“…Few studies have explored the mechanisms coupling estrogen signals to metabolic demand in endothelial cells. We recently showed that 17β‐estradiol (E2)…”
Get full text
Journal Article -
18
Effects of digitoxin on cell migration in ovarian cancer inflammatory microenvironment
Published in Biochemical pharmacology (01-08-2018)“…[Display omitted] Clinical and experimental evidence supports a role for cardiac glycosides (CGs) as potential novel anticancer drugs. However, there are no…”
Get full text
Journal Article -
19
Effects of Canrenone on Aorta and Right Ventricle of the Rat
Published in Journal of cardiovascular pharmacology (01-05-2001)“…Canrenone is a major active metabolite of spironolactone and, in addition to the antimineralocorticoid effect, shares with the parent compound the action as a…”
Get full text
Journal Article -
20
Increased dietary levels of α-linoleic acid inhibit mammary tumor growth and metastasis
Published in European journal of nutrition (01-03-2017)“…Objective The aim of this study was to determine whether α-linolenic acid (ALA ω-3 fatty acid) enriched diet affects growth parameters when applied to a…”
Get full text
Journal Article