Search Results - "Trevino, José"
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GSK3 suppression upregulates β-catenin and c-Myc to abrogate KRas-dependent tumors
Published in Nature communications (04-12-2018)“…Mutant KRas is a significant driver of human oncogenesis and confers resistance to therapy, underscoring the need to develop approaches that disable mutant…”
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2
Malignant otitis externa: An updated review
Published in American journal of otolaryngology (01-03-2021)“…Malignant otitis externa is a progressive infection of the external auditory canal and skull base. Pseudomonas aeruginosa is the most isolated microorganism…”
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3
Tension Distribution in Articular Surfaces of the Rotator Cable and Crescent: A Cadaveric Study
Published in Journal of bone and joint surgery. American volume (19-06-2024)“…The rotator cable functions as a stress and/or load transfer structure. Some studies suggested that a disruption of the cable negatively affects shoulder…”
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Strain distribution in the bursal rotator cuff based on whole‐muscle and muscle subregion‐specific loading: A cadaveric study
Published in Journal of orthopaedic research (01-09-2023)“…Rotator cuff (RC) tears are common injuries leading to significant dysfunction of the shoulder. Rotator cuff tears alter tension and strain in muscles and…”
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5
The Current Treatment Paradigm for Pancreatic Ductal Adenocarcinoma and Barriers to Therapeutic Efficacy
Published in Frontiers in oncology (15-07-2021)“…Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis, with a median survival time of 10-12 months. Clinically, these poor outcomes are attributed to…”
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6
Moment arms of the anatomical subregions of the rotator cuff muscles during shoulder rotation
Published in Clinical biomechanics (Bristol) (01-07-2023)“…Rotator cuff muscles are responsible for humeral rotation. Moment arms of different regions of these muscles during humeral rotation were analyzed in neutral…”
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7
The Microbiota and Cancer Cachexia
Published in International journal of molecular sciences (12-12-2019)“…Cancer cachexia is a multifactorial syndrome defined by weight loss, muscle wasting, and systemic inflammation. It affects the majority of patients with…”
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8
Long-Term Gemcitabine Treatment Reshapes the Pancreatic Tumor Microenvironment and Sensitizes Murine Carcinoma to Combination Immunotherapy
Published in Cancer research (Chicago, Ill.) (01-08-2020)“…Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer-related death with a median survival time of 6-12 months. Most patients present with…”
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9
Transcriptomic analysis of pancreatic adenocarcinoma specimens obtained from Black and White patients
Published in PloS one (22-02-2023)“…In pancreatic cancer clinical trials, Black patients are under-represented while having higher morbidity and mortality rates as compared to other racial…”
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10
Moment arms from the anatomical subregions of the rotator cuff muscles during flexion
Published in Journal of biomechanics (01-11-2022)“…Rotator cuff (RC) muscles act as force couples to stabilize the glenohumeral joint and enable shoulder motion. We investigated the moment arms of anatomical…”
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11
Dual Farnesyl and Geranylgeranyl Transferase Inhibitor Thwarts Mutant KRAS-Driven Patient-Derived Pancreatic Tumors
Published in Clinical cancer research (01-10-2019)“…Mutant KRAS is a major driver of pancreatic oncogenesis and therapy resistance, yet KRAS inhibitors are lacking in the clinic. KRAS requires farnesylation for…”
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12
EGFR/Src/Akt signaling modulates Sox2 expression and self-renewal of stem-like side-population cells in non-small cell lung cancer
Published in Molecular cancer (25-09-2012)“…Cancer stem cells are thought to be responsible for the initiation and progression of cancers. In non-small cell lung cancers (NSCLCs), Hoechst 33342 dye…”
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13
Diversity and Inclusion in Pancreatic Cancer Clinical Trials
Published in Gastroenterology (New York, N.Y. 1943) (01-12-2021)Get full text
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14
Diversification of Academic Surgery, Its Leadership, and the Importance of Intersectionality
Published in JAMA surgery (01-08-2021)“…Diversity in academic surgery is lacking, particularly among positions of leadership. To evaluate trends among racial/ethnical minority groups stratified by…”
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15
Robotic cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: is there a benefit?
Published in Surgical endoscopy (16-10-2024)“…Open cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is a therapeutic option for the management of malignancies with…”
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16
Removal of naphthalene and phenanthrene in synthetic solutions by electro-oxidation coupled with membrane bioreactor
Published in Environmental science and pollution research international (01-09-2021)“…Naphthalene (NAPH) and phenanthrene (PHEN) are two of the most abundant polycyclic aromatic hydrocarbons (PAHs) found in nature, and they are considered in the…”
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17
Nanosorbents as Materials for Extraction Processes of Environmental Contaminants and Others
Published in Molecules (Basel, Switzerland) (05-02-2022)“…The aim of this work focuses on the application of nanomaterials (NMs) in different sorptive extraction techniques for the analysis of organic contaminants…”
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18
Three-dimensional quantitative measurements of atrophy and fat infiltration in sub-regions of the supraspinatus muscle show heterogeneous distributions: a cadaveric study
Published in Archives of orthopaedic and trauma surgery (01-07-2022)“…Introduction Rotator cuff tears are common in the older population. Atrophy and fat infiltration develop un-evenly in torn supraspinatus (SSP) muscles leading…”
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Nicotine Induces Inhibitor of Differentiation-1 in a Src-dependent Pathway Promoting Metastasis and Chemoresistance in Pancreatic Adenocarcinoma
Published in Neoplasia (New York, N.Y.) (01-12-2012)“…Smoking is a significant risk factor for pancreatic cancer, but the molecular mechanisms by which tobacco smoke components promote the growth and progression…”
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A novel regimen for pancreatic ductal adenocarcinoma targeting MEK, BCL-xL, and EGFR
Published in Neoplasia (New York, N.Y.) (01-01-2025)“…•Oncogenic KRAS, the key driver for PDAC, currently lacks effective targeting therapy.•Triple inhibition of MEK, BCL-xL and EGFR showed enhanced tumor…”
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