Search Results - "Tretbar, U. Sandy"

Comparison of two lab-scale protocols for enhanced mRNA-based CAR-T cell generation and functionality by von Auw, Nadine, Serfling, Robert, Kitte, Reni, Hilger, Nadja, Zhang, Chengkang, Gebhardt, Clara, Duenkel, Anna, Franz, Paul, Koehl, Ulrike, Fricke, Stephan, Tretbar, U. Sandy

“…Process development for transferring lab-scale research workflows to automated manufacturing procedures is critical for chimeric antigen receptor (CAR)-T cell…”
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Conformational dynamics of stem II of the U2 snRNA by Rodgers, Margaret L, Tretbar, U Sandy, Dehaven, Alexander, Alwan, Amir A, Luo, George, Mast, Hannah M, Hoskins, Aaron A

“…The spliceosome undergoes dramatic changes in both small nuclear RNA (snRNA) composition and structure during assembly and pre-mRNA splicing. It has been…”
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Humanized mouse model: Hematopoietic stemcell transplantation and tracking using short tandem repeat technology by Walcher, Lia, Hilger, Nadja, Wege, Anja K., Lange, Franziska, Tretbar, U. Sandy, Blaudszun, André‐René, Fricke, Stephan

“…Introduction Models of mice carrying a human immune system, so‐called humanized mice, are used increasingly as preclinical models to bridge the gap between…”
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Lipid nanoparticles outperform electroporation in mRNA-based CAR T cell engineering by Kitte, Reni, Rabel, Martin, Geczy, Reka, Park, Stella, Fricke, Stephan, Koehl, Ulrike, Tretbar, U. Sandy

“…Engineered T cells expressing chimeric antigen receptors (CARs) have been proven as efficacious therapies against selected hematological malignancies. However,…”
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Dynamics of the DEAD-box ATPase Prp5 RecA-like domains provide a conformational switch during spliceosome assembly by Beier, David H, Carrocci, Tucker J, van der Feltz, Clarisse, Tretbar, U Sandy, Paulson, Joshua C, Grabowski, Nikolai, Hoskins, Aaron A

“…Abstract The DEAD-box family of proteins are ATP-dependent, RNA-binding proteins implicated in many aspects of RNA metabolism. Pre-mRNA splicing in eukaryotes…”
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Chemical and Cytotoxic Activity of three main Sesquiterpenoids from Warburgia ugandensis by Kitte, Reni, Tretbar, Maik, Dluczek, Sarah, Beckmann, Lorenz, Marquardt, Peter, Duenkel, Anna, Schubert, Andreas, Fricke, Stephan, Tretbar, U. Sandy

“…[Display omitted] •Three sesquiterpenoids are efficiently isolated from Warburgia ugandensis stem bark in one process under mild conditions.•Warburgia…”
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U2 snRNA Conformation is Regulated by Cus2 to Facilitate Dead-Box Protein Loading by Tretbar, U. Sandy, Hoskins, Aaron

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Characterization of S. cerevisiae Phenotypes Associated with Cancer‐Causing Mutations in Hsh155p by Zoerner, Douglas, Luo, George, Carrocci, Tucker, Tretbar, U Sandy, Hoskins, Aaron

“…Abstract only The eukaryotic spliceosome is composed of five small nuclear ribonucleoproteins (snRNPs) and many other associated protein splicing factors. The…”
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