Search Results - "Trepanier, Janie B."
-
1
HSV usurps eukaryotic initiation factor 3 subunit M for viral protein translation: novel prevention target
Published in PloS one (27-07-2010)“…Prevention of genital herpes is a global health priority. B5, a recently identified ubiquitous human protein, was proposed as a candidate HSV entry receptor…”
Get full text
Journal Article -
2
HSV activates Akt to trigger calcium release and promote viral entry: novel candidate target for treatment and suppression
Published in The FASEB journal (01-07-2013)“…HSV triggers intracellular calcium release to promote viral entry. We hypothesized that Akt signaling induces the calcium responses and contributes to HSV…”
Get full text
Journal Article -
3
Herpes Simplex Virus 2 (HSV-2) Prevents Dendritic Cell Maturation, Induces Apoptosis, and Triggers Release of Proinflammatory Cytokines: Potential Links to HSV-HIV Synergy
Published in Journal of Virology (01-02-2013)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
4
Herpes simplex virus type 2 glycoprotein H interacts with integrin αvβ3 to facilitate viral entry and calcium signaling in human genital tract epithelial cells
Published in Journal of virology (01-09-2014)“…Herpes simplex virus (HSV) entry requires multiple interactions at the cell surface and activation of a complex calcium signaling cascade. Previous studies…”
Get full text
Journal Article -
5
Herpes Simplex Virus Type 2 Glycoprotein H Interacts with Integrin alpha v beta 3 To Facilitate Viral Entry and Calcium Signaling in Human Genital Tract Epithelial Cells
Published in Journal of virology (01-09-2014)“…Herpes simplex virus (HSV) entry requires multiple interactions at the cell surface and activation of a complex calcium signaling cascade. Previous studies…”
Get full text
Journal Article -
6
Characterization of HCV-infected people who inject drugs (PWID) in the setting of clinical care in Canada (CAPICA): A retrospective study
Published in Canadian liver journal (01-11-2020)“…BACKGROUND: People who use drugs (PWUD) are among the highest risk category for becoming infected with the hepatitis C virus (HCV) in Canada. There is a need…”
Get full text
Journal Article -
7
The Z-Profile Study: a multicenter, retrospective cohort study to assess the real-world use and effectiveness of elbasvir/grazoprevir in Canadian adult patients with chronic hepatitis C
Published in Canadian liver journal (01-08-2020)“…Background: Canada was the first country to approve elbasvir/grazoprevir (EBR/GZR) for the treatment of chronic HCV infection for genotypes 1 and 4 with or…”
Get full text
Journal Article -
8
Reduction in intracellular HCV RNA and virus protein expression in human hepatoma cells following treatment with 2′- O -methyl-modified anti-core deoxyribozyme
Published in Virology (New York, N.Y.) (01-08-2008)“…Abstract HCV RNA is gaining greater consideration as a principal target for newer HCV antivirals because its destruction has the potential of eliminating the…”
Get full text
Journal Article -
9
Oligonucleotide-based therapeutic options against hepatitis C virus infection
Published in Antiviral therapy (01-01-2006)“…The hepatitis C virus (HCV) is the cause of a silent pandemic that, due to the chronic nature of the disease and the absence of curative therapy, continues to…”
Get full text
Journal Article