Search Results - "Trepanier, Catherine"

Regulation of NMDA receptors by the tyrosine kinase Fyn by Trepanier, Catherine H., Jackson, Michael F., MacDonald, John F.

“…The phosphorylation and trafficking of N‐methyl‐d‐aspartate (NMDA) receptors are tightly regulated by the Src family tyrosine kinase Fyn, through dynamic…”
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Neuroinflammation in Alzheimer's disease: are NSAIDs and selective COX-2 inhibitors the next line of therapy? by Trepanier, Catherine H, Milgram, Norton W

“…Alzheimer's disease (AD) is currently treated with cholinergic and glutamatergic therapies, which provide symptomatic benefit but do not reverse the underlying…”
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Metaplasticity gated through differential regulation of GluN2A versus GluN2B receptors by Src family kinases by Yang, Kai, Trepanier, Catherine, Sidhu, Bikram, Xie, Yu-Feng, Li, Hongbin, Lei, Gang, Salter, Michael W, Orser, Beverley A, Nakazawa, Takanobu, Yamamoto, Tadashi, Jackson, Michael F, MacDonald, John F

“…Metaplasticity is a higher form of synaptic plasticity that is essential for learning and memory, but its molecular mechanisms remain poorly understood. Here,…”
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Fyn, a potential target for Alzheimer's disease by Yang, Kai, Belrose, Jillian, Trepanier, Catherine H, Lei, Gang, Jackson, Michael F, MacDonald, John F

“…Alzheimer's disease (AD) is the most common form of dementia characterized by the presence of amyloid-β (Aβ) plaques and neurofibrillary tangles. The…”
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Infantile Spasms and Down Syndrome: A New Animal Model by Cortez, Miguel A, Shen, Liqing, Wu, Ying, Aleem, Ilyas S, Trepanier, Catherine H, Sadeghnia, Hamid R, Ashraf, Asim, Kanawaty, Ashlin, Liu, Chen-Chu, Stewart, Lee, Snead, O Carter

“…Infantile spasms is a catastrophic childhood seizure disorder for which few animal models exist. Children with Down syndrome are highly susceptible to…”
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Platelet-derived Growth Factor Selectively Inhibits NR2B-containing N-Methyl-D-aspartate Receptors in CA1 Hippocampal Neurons by Beazely, Michael A., Lim, Aeni, Li, Hongbin, Trepanier, Catherine, Chen, XuanMao, Sidhu, Bikram, MacDonald, John F.

“…Platelet-derived growth factor (PDGF) β receptor activation inhibits N-methyl-d-aspartate (NMDA)-evoked currents in hippocampal and cortical neurons via the…”
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Vasoactive intestinal peptide acts via multiple signal pathways to regulate hippocampal NMDA receptors and synaptic transmission by Yang, Kai, Trepanier, Catherine H., Li, Hongbin, Beazely, Michael A., Lerner, Ethan A., Jackson, Michael F., MacDonald, John F.

“…Vasoactive intestinal peptide (VIP) is a 28‐amino acid peptide, which belongs to a superfamily of structurally related peptide hormones including pituitary…”
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Group II metabotropic glutamate receptors modify N-methyl-D-aspartate receptors via Src kinase by Trepanier, Catherine, Lei, Gang, Xie, Yu-Feng, MacDonald, John F.

“…Group II metabotropic glutamate receptors (mGluR2/3) have emerged as important targets for the treatment of schizophrenia. Since hypofunction of…”
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Plasticity of synaptic glun receptors is required for the Src-dependent induction of long-term potentiation at CA3-CA1 synapses by Li, Hong-Bin, Jackson, Michael F., Yang, Kai, Trepanier, Catherine, Salter, Michael W., Orser, Beverley A., MacDonald, John F.

“…The induction of long‐term potentiation (LTP) of CA3‐CA1 synapses requires activation of postsynaptic N‐methyl‐D‐aspartate receptors (GluNRs). At resting…”
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Metaplasticity gated through differential regulation of GluN2A versus GluN2B receptors by Src family kinases: Metaplasticity gated through differential regulation of NMDA receptors by Yang, Kai, Trepanier, Catherine, Sidhu, Bikram, Xie, Yu-Feng, Li, Hongbin, Lei, Gang, Salter, Michael W, Orser, Beverley A, Nakazawa, Takanobu, Yamamoto, Tadashi, Jackson, Michael F, MacDonald, John F

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Platelet-derived Growth Factor Selectively Inhibits NR2B-containing N-Methyl-D-aspartate Receptors in CA1 Hippocampal NeuronsS by Beazely, Michael A., Lim, Aeni, Li, Hongbin, Trepanier, Catherine, Chen, XuanMao, Sidhu, Bikram, MacDonald, John F.

“…Platelet-derived growth factor (PDGF) β receptor activation inhibits N -methyl- d -aspartate (NMDA)-evoked currents in hippocampal and cortical neurons via the…”
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