Search Results - "Trentelman, Jos J. A."
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Counterattacking the tick bite: towards a rational design of anti-tick vaccines targeting pathogen transmission
Published in Parasites & vectors (14-05-2019)“…Hematophagous arthropods are responsible for the transmission of a variety of pathogens that cause disease in humans and animals. Ticks of the Ixodes ricinus…”
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Probing an Ixodes ricinus salivary gland yeast surface display with tick-exposed human sera to identify novel candidates for an anti-tick vaccine
Published in Scientific reports (03-08-2021)“…In Europe, Ixodes ricinus is the most important vector of human infectious diseases, most notably Lyme borreliosis and tick-borne encephalitis virus. Multiple…”
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A combined transcriptomic approach to identify candidates for an anti-tick vaccine blocking B. afzelii transmission
Published in Scientific reports (18-11-2020)“…Ixodes ricinus is the vector for Borrelia afzelii , the predominant cause of Lyme borreliosis in Europe, whereas Ixodes scapularis is the vector for Borrelia…”
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Tick-Tattoo: DNA Vaccination Against B. burgdorferi or Ixodes scapularis Tick Proteins
Published in Frontiers in immunology (25-02-2021)“…sensu lato (sl) is the causative agent of Lyme borreliosis. Currently there is no human vaccine against Lyme borreliosis, and most research focuses on…”
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Identification of novel conserved Ixodes vaccine candidates; a promising role for non-secreted salivary gland proteins
Published in Vaccine (12-12-2022)“…Ixodes ricinus and Ixodes scapularis are the main vectors for the causative agents of Lyme borreliosis and a wide range of other pathogens. Repeated tick-bites…”
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Identification of Tick Ixodes ricinus Midgut Genes Differentially Expressed During the Transmission of Borrelia afzelii Spirochetes Using a Transcriptomic Approach
Published in Frontiers in immunology (04-02-2021)“…Lyme borreliosis is an emerging tick-borne disease caused by spirochetes sensu lato. In Europe, Lyme borreliosis is predominantly caused by and transmitted by…”
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The Ixodes ricinus salivary gland proteome during feeding and B. Afzelii infection: New avenues for an anti-tick vaccine
Published in Vaccine (17-03-2023)“…Borrelia burgdorferi sensu lato, the causative agents of Lyme borreliosis, are transmitted by Ixodes ticks. Tick saliva proteins are instrumental for survival…”
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A combination of antibodies against Bm86 and Subolesin inhibits engorgement of Rhipicephalus australis (formerly Rhipicephalus microplus) larvae in vitro
Published in Parasites & vectors (25-07-2019)“…Rhipicephalus microplus is a hard tick species that has a high impact on cattle health and production in tropical and subtropical regions. Recently, ribosomal…”
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Borrelia miyamotoi Activates Human Dendritic Cells and Elicits T Cell Responses
Published in The Journal of immunology (1950) (15-01-2020)“…The spirochete has recently been shown to cause relapsing fever. Like the Lyme disease agent, is transmitted through the bite of infected ticks; however,…”
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A new method for in vitro feeding of Rhipicephalus australis (formerly Rhipicephalus microplus) larvae: a valuable tool for tick vaccine development
Published in Parasites & vectors (23-03-2017)“…Rhipicephalus microplus is a hard tick that has a major impact on cattle health in tropical and subtropical regions because it feeds on cattle and is…”
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Rapid DNA vaccination against Burkholderia pseudomallei flagellin by tattoo or intranasal application
Published in Virulence (17-11-2017)“…Melioidosis is a severe infectious disease with a high mortality that is endemic in South-East Asia and Northern Australia. The causative pathogen,…”
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