Search Results - "Trentalance, Anna"

Sex differences in hepatic regulation of cholesterol homeostasis by De Marinis, Elisabetta, Martini, Chiara, Trentalance, Anna, Pallottini, Valentina

“…Physiological sex differences may influence metabolic status and then alter the onset of some diseases. According to recent studies, it is now well established…”
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Biphasic estradiol-induced AKT phosphorylation is modulated by PTEN via MAP kinase in HepG2 cells by Marino, Maria, Acconcia, Filippo, Trentalance, Anna

“…We reported previously in HepG2 cells that estradiol induces cell cycle progression throughout the G1-S transition by the parallel stimulation of both…”
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Rat HMGCoA reductase activation in thioacetamide-induced liver injury is related to an increased reactive oxygen species content by Pallottini, Valentina, Martini, Chiara, Bassi, Anna M., Romano, Paola, Nanni, Giorgio, Trentalance, Anna

“…In thioacetamide-induced liver injury a modification of isoprenoid content and an increase of reactive oxygen species has been described. We have examined how…”
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Modified HMG-CoA reductase and LDLr regulation is deeply involved in age-related hypercholesterolemia by Pallottini, Valentina, Martini, Chiara, Cavallini, Gabriella, Donati, Alessio, Bergamini, Ettore, Notarnicola, Maria, Caruso, Maria Gabriella, Trentalance, Anna

“…During the ageing process in rats hypercholesterolemia occurs in concert with full activation, lowered degradation rate and an unchanged level of the rate…”
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Caloric restrictions affect some factors involved in age-related hypercholesterolemia by Martini, Chiara, Pallottini, Valentina, Cavallini, Gabriella, Donati, Alessio, Bergamini, Ettore, Trentalance, Anna

“…Ageing has been defined as a progressive decrease in physiological capacity and a reduced ability to respond to environmental stresses. It has been observed…”
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The Promoter of the Rat 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Gene Contains a Tissue-Specific Estrogen-Responsive Region by Di Croce, Luciano, Vicent, Guillermo P, Pecci, Adali, Bruscalupi, Giovannella, Trentalance, Anna, Beato, Miguel

“…The isoprenoid metabolic pathway is mainly regulated at the level of conversion of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) to mevalonate, catalyzed by…”
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Palmitoylation-dependent Estrogen Receptor α Membrane Localization: Regulation by 17β-Estradiol by Acconcia, Filippo, Ascenzi, Paolo, Bocedi, Alessio, Spisni, Enzo, Tomasi, Vittorio, Trentalance, Anna, Visca, Paolo, Marino, Maria

“…A fraction of the nuclear estrogen receptor α (ERα) is localized to the plasma membrane region of 17β-estradiol (E2) target cells. We previously reported that…”
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Survival versus apoptotic 17β-estradiol effect: Role of ERα and ERβ activated non-genomic signaling by Acconcia, Filippo, Totta, Pierangela, Ogawa, Sumito, Cardillo, Irene, Inoue, Satoshi, Leone, Stefano, Trentalance, Anna, Muramatsu, Masami, Marino, Maria

“…The capability of 17β‐estradiol (E2) to induce the non‐genomic activities of its receptors (ERα and ERβ) and to evoke different signaling pathways committed to…”
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Distinct Nongenomic Signal Transduction Pathways Controlled by 17β-Estradiol Regulate DNA Synthesis and Cyclin D1 Gene Transcription in HepG2 Cells by Marino, Maria, Acconcia, Filippo, Bresciani, Francesco, Weisz, Alessandro, Trentalance, Anna

“…Estrogens induce cell proliferation in target tissues by stimulating progression through the G1 phase of the cell cycle. Activation of cyclin D 1 gene…”
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Regulation of HMG-CoA reductase expression by hypoxia by Pallottini, Valentina, Guantario, Barbara, Martini, Chiara, Totta, Pierangela, Filippi, Irene, Carraro, Fabio, Trentalance, Anna

“…The ability to maintain O2 homeostasis is essential to the survival of all invertebrate and vertebrate species. The transcriptional factor, hypoxia inducible…”
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Distinct Nongenomic Signal Transduction Pathways Controlled by 17β-Estradiol Regulate DNA Synthesis and Cyclin D 1 Gene Transcription in HepG2 Cells by Marino, Maria, Acconcia, Filippo, Bresciani, Francesco, Weisz, Alessandro, Trentalance, Anna

“…Estrogens induce cell proliferation in target tissues by stimulating progression through the G1 phase of the cell cycle. Activation of cyclin D 1 gene…”
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3-hydroxy 3-methylglutaryl coenzyme A reductase increase is essential for rat muscle differentiation by Martini, Chiara, Trapani, Laura, Narciso, Laura, Marino, Maria, Trentalance, Anna, Pallottini, Valentina

“…3‐Hydroxy 3‐methylglutaryl coenzyme A reductase (HMG‐CoAR) is the key and rate‐limiting enzyme of cholesterol biosynthetic pathway. Although HMG‐CoAR activity…”
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Mechanism underlying long-term regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase during L6 myoblast differentiation by Trapani, Laura, Martini, Chiara, Trentalance, Anna, Pallottini, Valentina

“…3‐Hydroxy 3‐methylglutaryl Coenzyme A reductase (HMG‐CoAR) and its end‐products are crucial for insulin‐induced differentiation of fetal rat myoblasts (L6)…”
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Age-related HMG-CoA reductase deregulation depends on ROS-induced p38 activation by Pallottini, Valentina, Martini, Chiara, Cavallini, Gabriella, Bergamini, Ettore, Mustard, Kirsty J., Hardie, D. Grahame, Trentalance, Anna

“…It seems to be clear that hepatic age-related HMG-CoA reductase total activation is connected to a rise of reactive oxygen species (ROS). However, the…”
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3-Hydroxy 3-Methylglutaryl Coenzyme A Reductase: a New Biomarker of Fish Exposure to Water Pollution by Pallottini, Valentina, Scalici, Massimiliano, Gibertini, Giancarlo, Marino, Maria, Trentalance, Anna

“…The aim of this study was to identify a new putative biomarker in Salmo trutta exposed to water pollution. Variations in the levels of hepatic 3-hydroxy…”
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Changes in plasma dolichol levels, transport, and hepatic delivery during rat liver regeneration by Marino, M, Bruscalupi, G, Manzi, P, Rivabene, R, Trentalance, A

“…During the proliferative process that follows partial hepatectomy in the rat, the dolichol content increases in both plasma and liver. Its transport in the…”
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Omega-3 as well as caloric restriction prevent the age-related modifications of cholesterol metabolism by Martini, Chiara, Pallottini, Valentina, De Marinis, Elisabetta, Marino, Maria, Cavallini, Gabriella, Donati, Alessio, Straniero, Sara, Trentalance, Anna

“…Intracellular concentration of cholesterol is regulated by the balance between endogenous synthesis and exogenous uptake; endogenous synthesis is subject to…”
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Stimulation of autophagy by antilipolytic drugs may rescue rodents from age-associated hypercholesterolemia by Straniero, Sara, Cavallini, Gabriella, Donati, Alessio, Pallottini, Valentina, Martini, Chiara, Trentalance, Anna, Bergamini, Ettore

“…Aging is characterized by several metabolic changes responsible for the decline of certain functions and the appearance of age-related diseases, including…”
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3-Hydroxy-3-methylglutaryl coenzyme A reductase deregulation and age-related hypercholesterolemia: A new role for ROS by Pallottini, Valentina, Martini, Chiara, Pascolini, Andrea, Cavallini, Gabriella, Gori, Zina, Bergamini, Ettore, Incerpi, Sandra, Trentalance, Anna

“…The microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCoAR) is the rate-limiting enzyme in cholesterol synthesis and is highly regulated by…”
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Mechanisms underlying the impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in aged rat liver by Pallottini, Valentina, Montanari, Laura, Cavallini, Gabriella, Bergamini, Ettore, Gori, Zina, Trentalance, Anna

“…As the main risk factor for cardiovascular disease, hypercholesterolemia is one of the most studied age-related metabolic alterations. In the liver,…”
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