Search Results - "Trent, Jeff"

Targeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein by Salanti, Ali, Clausen, Thomas M., Agerbæk, Mette Ø., Al Nakouzi, Nader, Dahlbäck, Madeleine, Oo, Htoo Z., Lee, Sherry, Gustavsson, Tobias, Rich, Jamie R., Hedberg, Bradley J., Mao, Yang, Barington, Line, Pereira, Marina A., LoBello, Janine, Endo, Makoto, Fazli, Ladan, Soden, Jo, Wang, Chris K., Sander, Adam F., Dagil, Robert, Thrane, Susan, Holst, Peter J., Meng, Le, Favero, Francesco, Weiss, Glen J., Nielsen, Morten A., Freeth, Jim, Nielsen, Torsten O., Zaia, Joseph, Tran, Nhan L., Trent, Jeff, Babcook, John S., Theander, Thor G., Sorensen, Poul H., Daugaard, Mads

“…Plasmodium falciparum engineer infected erythrocytes to present the malarial protein, VAR2CSA, which binds a distinct type chondroitin sulfate (CS) exclusively…”
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Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma by Cloughesy, Tim F, Yoshimoto, Koji, Nghiemphu, Phioanh, Brown, Kevin, Dang, Julie, Zhu, Shaojun, Hsueh, Teli, Chen, Yinan, Wang, Wei, Youngkin, David, Liau, Linda, Martin, Neil, Becker, Don, Bergsneider, Marvin, Lai, Albert, Green, Richard, Oglesby, Tom, Koleto, Michael, Trent, Jeff, Horvath, Steve, Mischel, Paul S, Mellinghoff, Ingo K, Sawyers, Charles L

“…There is much discussion in the cancer drug development community about how to incorporate molecular tools into early-stage clinical trials to assess target…”
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Multiethnic PDX models predict a possible immune signature associated with TNBC of African ancestry by Jiagge, Evelyn M., Ulintz, Peter J., Wong, Shukmei, McDermott, Sean P., Fossi, Sabrina I., Suhan, Tahra K., Hoenerhoff, Mark J., Bensenhaver, Jessica M., Salem, Barbara, Dziubinski, Michele, Oppong, Joseph K., Aitpillah, Francis, Ishmael, Kyei, Osei-Bonsu, Ernest, Adjei, Ernest, Baffour, Awuah, Aldrich, Jessica, Kurdoglu, Ahmet, Fernando, Kurt, Craig, David W., Trent, Jeff M., Li, Jun, Chitale, Dhananjay, Newman, Lisa A., Carpten, John D., Wicha, Max S., Merajver, Sofia D.

“…Purpose Triple-negative breast cancer (TNBC) is an aggressive subtype most prevalent among women of Western Sub-Saharan African ancestry. It accounts for…”
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A genome-wide scan for naevus count: linkage to CDKN2A and to other chromosome regions by Zhu, Gu, Montgomery, Grant W, James, Michael R, Trent, Jeff M, Hayward, Nicholas K, Martin, Nicholas G, Duffy, David L

“…High numbers of melanocytic naevi (moles), and mutations in the p16 gene (CDKN2A), are two strong risk factors for cutaneous malignant melanoma. We have…”
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A genome-wide scan for naevus count: linkage to CDKN2A and to other chromosome regions by GU ZHU, MONTGOMERY, Grant W, JAMES, Michael R, TRENT, Jeff M, HAYWARD, Nicholas K, MARTIN, Nicholas G, DUFFY, David L

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Nivolumab plus ipilimumab with or without live bacterial supplementation in metastatic renal cell carcinoma: a randomized phase 1 trial by Dizman, Nazli, Meza, Luis, Bergerot, Paulo, Alcantara, Marice, Dorff, Tanya, Lyou, Yung, Frankel, Paul, Cui, Yujie, Mira, Valerie, Llamas, Marian, Hsu, Joann, Zengin, Zeynep, Salgia, Nicholas, Salgia, Sabrina, Malhotra, Jasnoor, Chawla, Neal, Chehrazi-Raffle, Alex, Muddasani, Ramya, Gillece, John, Reining, Lauren, Trent, Jeff, Takahashi, Motomichi, Oka, Kentaro, Higashi, Seiya, Kortylewski, Marcin, Highlander, Sarah K., Pal, Sumanta K.

“…Previous studies have suggested that the gut microbiome influences the response to checkpoint inhibitors (CPIs) in patients with cancer. CBM588 is a…”
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Initial genome sequencing and analysis of multiple myeloma by Chapman, Michael A., Lawrence, Michael S., Keats, Jonathan J., Cibulskis, Kristian, Sougnez, Carrie, Schinzel, Anna C., Harview, Christina L., Brunet, Jean-Philippe, Ahmann, Gregory J., Adli, Mazhar, Anderson, Kenneth C., Ardlie, Kristin G., Auclair, Daniel, Baker, Angela, Bergsagel, P. Leif, Bernstein, Bradley E., Drier, Yotam, Fonseca, Rafael, Gabriel, Stacey B., Hofmeister, Craig C., Jagannath, Sundar, Jakubowiak, Andrzej J., Krishnan, Amrita, Levy, Joan, Liefeld, Ted, Lonial, Sagar, Mahan, Scott, Mfuko, Bunmi, Monti, Stefano, Perkins, Louise M., Onofrio, Robb, Pugh, Trevor J., Rajkumar, S. Vincent, Ramos, Alex H., Siegel, David S., Sivachenko, Andrey, Stewart, A. Keith, Trudel, Suzanne, Vij, Ravi, Voet, Douglas, Winckler, Wendy, Zimmerman, Todd, Carpten, John, Trent, Jeff, Hahn, William C., Garraway, Levi A., Meyerson, Matthew, Lander, Eric S., Getz, Gad, Golub, Todd R.

“…Multiple myeloma is an incurable malignancy of plasma cells, and its pathogenesis is poorly understood. Here we report the massively parallel sequencing of 38…”
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Promiscuous Mutations Activate the Noncanonical NF-κB Pathway in Multiple Myeloma by Keats, Jonathan J., Fonseca, Rafael, Chesi, Marta, Schop, Roelandt, Baker, Angela, Chng, Wee-Joo, Van Wier, Scott, Tiedemann, Rodger, Shi, Chang-Xin, Sebag, Michael, Braggio, Esteban, Henry, Travis, Zhu, Yuan-Xiao, Fogle, Homer, Price-Troska, Tammy, Ahmann, Gregory, Mancini, Catherine, Brents, Leslie A., Kumar, Shaji, Greipp, Philip, Dispenzieri, Angela, Bryant, Barb, Mulligan, George, Bruhn, Laurakay, Barrett, Michael, Valdez, Riccardo, Trent, Jeff, Stewart, A. Keith, Carpten, John, Bergsagel, P. Leif

“…Activation of NF-κB has been noted in many tumor types, however only rarely has this been linked to an underlying genetic mutation. An integrated analysis of…”
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Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing by Fang, Li Tai, Zhu, Bin, Zhao, Yongmei, Chen, Wanqiu, Yang, Zhaowei, Kerrigan, Liz, Langenbach, Kurt, de Mars, Maryellen, Lu, Charles, Idler, Kenneth, Jacob, Howard, Zheng, Yuanting, Ren, Luyao, Yu, Ying, Jaeger, Erich, Schroth, Gary P., Abaan, Ogan D., Talsania, Keyur, Lack, Justin, Shen, Tsai-Wei, Chen, Zhong, Stanbouly, Seta, Tran, Bao, Shetty, Jyoti, Kriga, Yuliya, Meerzaman, Daoud, Nguyen, Cu, Petitjean, Virginie, Sultan, Marc, Cam, Margaret, Mehta, Monika, Hung, Tiffany, Peters, Eric, Kalamegham, Rasika, Sahraeian, Sayed Mohammad Ebrahim, Mohiyuddin, Marghoob, Guo, Yunfei, Yao, Lijing, Song, Lei, Lam, Hugo Y. K., Drabek, Jiri, Vojta, Petr, Maestro, Roberta, Gasparotto, Daniela, Kõks, Sulev, Reimann, Ene, Scherer, Andreas, Nordlund, Jessica, Liljedahl, Ulrika, Jensen, Roderick V., Pirooznia, Mehdi, Li, Zhipan, Xiao, Chunlin, Sherry, Stephen T., Kusko, Rebecca, Moos, Malcolm, Donaldson, Eric, Tezak, Zivana, Ning, Baitang, Tong, Weida, Li, Jing, Duerken-Hughes, Penelope, Catalanotti, Claudia, Maheshwari, Shamoni, Shuga, Joe, Liang, Winnie S., Keats, Jonathan, Adkins, Jonathan, Tassone, Erica, Zismann, Victoria, McDaniel, Timothy, Trent, Jeffrey, Foox, Jonathan, Butler, Daniel, Mason, Christopher E., Hong, Huixiao, Shi, Leming, Wang, Charles, Xiao, Wenming

“…The lack of samples for generating standardized DNA datasets for setting up a sequencing pipeline or benchmarking the performance of different algorithms…”
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A layered perceptron approach to categorizing cDNA microarray measurements by Ringner, Markus, Peterson, Carsten, Gruvberger, Sofia, Fernö, Mårten, Borg, Åke, Khan, Javed, Wei, Jun, Saal, Lao, Chen, Yidong, Ladanyi, Marc, Meltzer, Paul S., Trent, Jeff M.

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Abstract B01: Sustained clinical response to treatment directed by genomic expression profiling suggests mTOR signaling is an effective target in choroid plexus carcinoma by Cornelius, Albert S., Foley, Jessica, Mitchell, Deanna, Nagulapally, Abhinav, Bond, Jeff, Huntelman, Matthew, Corneveaux, Jason, Trent, Jeff, Sholler, Giselle

“…Abstract Background: Choroid plexus tumors comprise 10-20% of intracranial tumors in children less than one year of age, the majority of these are benign…”
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Abstract 5457: Contexts of vulnerability mediating TMZ response in metastatic melanoma by Yin, Holly, Brooks, Bradford, Chow, Donald, Sereduk, Chris, Sekulic, Aleksandar, Brown, Kevin, Trent, Jeff

“…Abstract Metastatic malignant melanoma is an incurable disease with average 5-year survival rates for patients with disseminated disease ranging from 5-18%…”
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Abstract B09: High-throughput RNAi sensitization screening identifies a novel drug combination for metastatic melanoma by Yin, Hongwei Holly, Chow, Donald, Sereduk, Chris, Aziz, Meraj, Kiefer, Jeff, Xu, Mai, Garside, Michael, Tang, Nanyun, Sima, Chao, Hua, Jianping, Kassner, Michelle, Bittner, Mike, Hayward, Nick, Brown, Kevin, Jeff, Trent

“…Abstract Metastatic malignant melanoma is an incurable disease with a poor 5-year survival rates. Despite the recent development of several novel therapeutic…”
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Direct cloning of human ovarian carcinoma cells in agar by Hamburger, A W, Salmon, S E, Kim, M B, Trent, J M, Soehnlen, B J, Alberts, D S, Schmidt, H J

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Abstract 5068: Identification of key tumorigenic pathways in never-smoker lung adenocarcinoma using massively parallel DNA and RNA sequencing and methylation profiling by Whitsett, Timothy G., Cherni, Irene, Inge, Landon, Salhia, Bodour, Fowler, Aaron, Bremner, Ross, Izatt, Tyler, Aldrich, Jessica, Kurdoglu, Ahmet, Christoforides, Alexis, Baker, Angela S., Phillips, Lori, Liang, Winnie S., Sinari, Shripad, Armstrong, Brock, Selinski, Cheryl, Betsou, Fay, Phillips, Robert, Trent, Jeff R., Von Hoff, Daniel D., Carpten, John D., Craig, David W., Weiss, Glen J., Tran, Nhan L.

“…Abstract Considered independently, lung cancer in never-smokers would rank among the ten most common causes of cancer mortality. Driver pathways and potential…”
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Abstract A43: Identification of key tumorigenic pathways in never-smoker lung adenocarcinoma patients using massively parallel DNA and RNA sequencing by Whitsett, Timothy G., Sinari, Shripad, Sheff, Kelly W., Cheung, Phillip Y., Ross, Julianna, Armstrong, Brock, Inge, Landon, Bremner, Ross, Selinsky, Cheryl, Betsou, Fay, Phillips, Robert, Cherni, Irene, Trent, Jeff M., Von Hoff, Daniel D., Carpten, John D., Craig, David W., Weiss, Glen J., Tran, Nhan L., Izatt, Tyler, Aldrich, Jessica, Kurdoglu, Ahmet, Christoforides, Alexis, Baker, Angela S., Phillips, Lori, Liang, Winnie S.

“…Abstract Lung cancer remains the leading cause of cancer deaths in the US and throughout the world. Never-smokers with lung cancer constitute an understudied…”
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APC binds to the novel protein EB1 by LI-KUO SU, BURRELL, M, HILL, D. E, GYURIS, J, BRENT, R, WILTSHIRE, R, TRENT, J, VOGELSTEIN, B, KINZLER, K. W

“…Mutations of the APC gene play a critical role in both sporadic and familial forms of colorectal cancer. The vast majority of these mutations result in the…”
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Opportunities and Barriers in the Age of Team Science: Strategies for Success by Sellers, Thomas A., Caporaso, Neil, Lapidus, Stan, Petersen, Gloria M., Trent, Jeff

“…Objective To provide the voice of experience to investigators contemplating engagement in the realm of "team science". Methods Leaders were brought together…”
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Independent amplification and frequent co-amplification of three nonsyntenic regions on the long arm of chromosome 20 in human breast cancer by TANNER, M. M, TIRKKONEN, M, MELTZER, P, KALLIONEIMI, O. P, KALLIONEIMI, A, ISOLA, J, KUUKASJÄRVI, T, COLLINS, C, KOWBEL, D, GUAN, X.-Y, TRENT, J, GRAY, J. W

“…DNA amplification at 20q13.2 is common in breast cancer, correlates with poor prognosis, and may reflect location of an important oncogene. Recently, other…”
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Promiscuous Mutations Activate the Non-Canonical NF-kB Pathway in Multiple Myeloma by Keats, Jonathan J., Fonseca, Rafael, Chesi, Marta, Schop, Roelandt, Baker, Angela, Chng, Wee-Joo, Van Wier, Scott, Tiedemann, Rodger, Shi, Chang-Xin, Sebag, Michael, Braggio, Esteban, Henry, Travis, Zhu, Yuan-Xiao, Fogle, Homer, Price-Troska, Tammy, Ahmann, Gregory, Mancini, Catherine, Brents, Leslie A., Kumar, Shaji, Greipp, Philip, Dispenzieri, Angela, Bryant, Barb, Mulligan, George, Bruhn, Laurakay, Barrett, Michael, Valdez, Riccardo, Trent, Jeff, Stewart, A. Keith, Carpten, John, Bergsagel, P. Leif

“…Activation of NF-kB has been noted in many tumor types, however only rarely has this been linked to an underlying genetic mutation. An integrated analysis of…”
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