Search Results - "Tremblay, Anne Marie K"
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STAT3 promotes IFNγ/TNFα‐induced muscle wasting in an NF‐κB‐dependent and IL‐6‐independent manner
Published in EMBO molecular medicine (01-05-2017)“…Cachexia is a debilitating syndrome characterized by involuntary muscle wasting that is triggered at the late stage of many cancers. While the multifactorial…”
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Tankyrase-1 regulates RBP-mediated mRNA turnover to promote muscle fiber formation
Published in Nucleic acids research (24-04-2024)“…Poly(ADP-ribosylation) (PARylation) is a post-translational modification mediated by a subset of ADP-ribosyl transferases (ARTs). Although…”
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Pharmacological or genetic inhibition of iNOS prevents cachexia‐mediated muscle wasting and its associated metabolism defects
Published in EMBO molecular medicine (07-07-2021)“…Cachexia syndrome develops in patients with diseases such as cancer and sepsis and is characterized by progressive muscle wasting. While iNOS is one of the…”
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Depletion of HuR in murine skeletal muscle enhances exercise endurance and prevents cancer-induced muscle atrophy
Published in Nature communications (13-09-2019)“…The master posttranscriptional regulator HuR promotes muscle fiber formation in cultured muscle cells. However, its impact on muscle physiology and function in…”
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The AMPK agonist 5‐aminoimidazole‐4‐carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation‐associated cachectic muscle wasting
Published in EMBO molecular medicine (01-07-2018)“…Activation of AMPK has been associated with pro‐atrophic signaling in muscle. However, AMPK also has anti‐inflammatory effects, suggesting that in cachexia, a…”
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6
STAT 3 promotes IFN γ/ TNF α‐induced muscle wasting in an NF ‐κB‐dependent and IL ‐6‐independent manner
Published in EMBO molecular medicine (01-05-2017)“…Cachexia is a debilitating syndrome characterized by involuntary muscle wasting that is triggered at the late stage of many cancers. While the multifactorial…”
Get full text
Journal Article